Results 61 to 70 of about 25,300,433 (384)

HO-1 expression control in the rat glomerulus

Biochemical and Biophysical Research Communications, 2015
The differential localization of HO-1 in renal cells under conditions of injury, and the demonstration that exaggerated HO-1 expression can have detrimental rather than beneficial effects, raises the question of whether HO-1 expression in these cells is subject to control.
Detsika, M.G., Duann, P., Lianos, E.A.
openaire   +3 more sources

Astaxanthin protects against MPP+-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis [PDF]

, 2012
BACKGROUND: Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders.
Bixia Huang, Qinyong Ye, Xiaochun Chen, Xiaodong Zhang, Yuangui Zhu   +4 more
core   +1 more source

Ethyl pyruvate ameliorates heat stroke-induced multiple organ dysfunction and inflammatory responses by induction of stress proteins and activation of autophagy in rats

International Journal of Hyperthermia, 2021
Objective: Heat stroke (HS) elicits the systemic inflammatory responses that result in multiple organ dysfunction (MOD). Heat shock response and autophagy are activated during heat stress for removal of damaged organelles and proteins, emerging as a ...
Je-Ming Hu, Chih-Hsueng Hsu, Yu-Chun Lin, Ching-Wen Kung, Shu-Ying Chen, Wen-Ting Lin, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee   +8 more
doaj   +1 more source

HO-1 extends to stem cells

Blood, 2008
In this issue of Blood , Cao and colleagues show that HO-1 plays a key role in the maintenance of HSCs by limiting the stress-induced proliferation of progenitors and the exhaustion of HSC populations.
openaire   +4 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases

Journal of Inflammation Research, 2021
Chien-Chung Yang,1,2 Chuen-Mao Yang3– 5 1Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Tao-Yuan, Kwei-San, Tao-Yuan, 33302, Taiwan; 2School of Traditional Chinese Medicine, College of Medicine, Chang Gung University ...
Yang CC, Yang CM
doaj  

Scrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling

Antioxidants, 2020
Scrophularia koraiensis Nakai (Scrophulariaceae) is a medicinal herb that grows in Korea and which has been widely used to treat fever, edema, neuritis and laryngitis.
Tae-Yang Jung, A Yeong Lee, Jun-Ho Song, Min Young Lee, Je-Oh Lim, Se-Jin Lee, Je-Won Ko, Na-Rae Shin, Jong-Choon Kim, In-Sik Shin, Joong-Sun Kim   +10 more
doaj   +1 more source

Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis

Arthritis Research & Therapy, 2019
IntroductionOsteoarthritis (OA) is an inflammatory disease of the joints that causes progressive disability in the elderly. Reactive oxygen species (ROS) play an important role in OA development; they may activate the NLRP3 inflammasome, thereby inducing
Zhuming Chen, H. Zhong, Jinsong Wei, S. Lin, Zhixian Zong, Fan Gong, Xinqia Huang, Jinhui Sun, Peng Li, Hao Lin, Bo Wei, Jiaqi Chu   +11 more
semanticscholar   +1 more source

HO-1 in Control of a Self-Eating Kidney [PDF]

Journal of the American Society of Nephrology, 2010
Autophagy, from Greek meaning self-eating, refers to the degradation of macromolecules and organelles by the lysosomal machinery of cells and is a tightly regulated and normally occurring process that helps maintain a balance among synthesis, degradation, and recycling of cellular components.
Pinelopi P, Kapitsinou, Volker H, Haase
openaire   +2 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source