Results 71 to 80 of about 456,511 (292)

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice [PDF]

, 2008
Background HO-1 participates in the degradation of heme. Its products can exert unique cytoprotective effects. Numerous tumors express high levels of HO-1 indicating that this enzyme might be a potential therapeutic target.
Dominika Nowis, Marek Bugajski, Magdalena Winiarska, Jacek Bil, Angelika Szokalska, Pawel Salwa, Tadeusz Issat, Halina Was, Alicja Jozkowicz, Jozef Dulak, Tomasz Stoklosa, Jakub Golab   +11 more
core   +2 more sources

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages

Journal of Inflammation Research, 2021
Tian-Yong Hu,1,* Hua Zhang,1,* Yan-Yan Chen,1 Wei-Hua Jiao,2 Jun-Ting Fan,3 Zhi-Qiang Liu,1 Hou-Wen Lin,2 Bao-Hui Cheng1 1Shenzhen Key Laboratory of ENT, Institute of ENT and Longgang ENT Hospital, Shenzhen, 518172, People’s Republic of China ...
Hu TY, Zhang H, Chen YY, Jiao WH, Fan JT, Liu ZQ, Lin HW, Cheng BH   +7 more
doaj  

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger, Laura Walz, Michael C. Frühwald, Stefan Lautenbacher, Miriam Kunz   +4 more
wiley   +1 more source

GDNF modulates HO-1 expression in substantia nigra postnatal cell cultures [PDF]

, 1964
Heme oxygenase-1 (HO-1) has been strongly highlighted because of its induction in many cell types by toxic stimuli, including oxidative stress. The intense HO-1 immunostaining in the substantia nigra of Parkinson disease (PD) patients suggests its ...
Saavedra, Ana, Baltazar, Graça, Carvalho, Caetana M., Duarte, Emília P.   +3 more
core  

Phenomenological Theory of Superconductivity and Magnetism in Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C

, 1999
The coexistence of the superconductivity and magnetism in the Ho$_{1-x}$Dy$_x$Ni$_2$B$_2$C is studied by using Ginzburg-Landau theory. This alloy shows the coexistence and complex interplay of superconducting and magnetic order.
A. Amici, A. Kreyssig, B. K. Cho, B. K. Cho, B. K. Cho, Hyeonjin Doh, J. W. Lynn, J. W. Lynn, K. D. D. Rathnayaka, L. F. Mattheiss, Manfred Sigrist, P. C. Canfield, P. C. Canfield, R. J. Cava, R. Nagarajan, S. V. Shulga, Sung-Ik Lee, T. E. Grigereit, T. Moriya, V. A. Kalatsky, W. E. Pickett   +20 more
core   +1 more source

Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene [PDF]

, 2013
Transforming growth factor-β (TGF-β) has multiple functions in embryogenesis, adult homeostasis, tissue repair, and development of cancer. Here, we report that TGF-β suppresses the transcriptional activation of the heme oxygenase-1 (HO-1) gene, which is ...
Igarashi Kazuhiko, Itoh Ken, Kamoshida Atsushi, Kato Mitsuyasu, Koinuma Daizo, Motohashi Hozumi, Ogami Tomohiro, Okita Yukari, Suzuki Hiroyuki, Yamamoto Masayuki, 加藤 光保, 鈴木 裕之   +11 more
core   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Induction of heme oxygenase-1 by hemin protects lung against orthotopic autologous liver transplantation-induced acute lung injury in rats [PDF]

, 2016
BACKGROUND: Post-liver transplantation acute lung injury (ALI) severely affects patients’ survival, whereas the mechanism is unclear and effective therapy is lacking.
Jun Cai, Na Guo, Wanling Gao, Weifeng Yao, Xinjin Chi, Yi Jin, Ziqing Hei   +6 more
core   +1 more source

Elucidating the Role of Nrf2 Signaling Pathway in Mycoplasma Infections

Frontiers in Bioscience-Landmark
Mycoplasmas are the smallest cell-wall-less self-replicating prokaryotes. Mycoplasma species can be found within and outside cells as “silent parasites” that live intracellularly and as membrane surface parasites.
Sarmistha Saha, Nadezhda Sachivkina, Olga Kuznetsova, Ekaterina Neborak, Natallia Zhabo   +4 more
doaj   +1 more source