CUT homeobox genes: transcriptional regulation of neuronal specification and beyond [PDF]
Frontiers in Cellular Neuroscience, 2023 CUT homeobox genes represent a captivating gene class fulfilling critical functions in the development and maintenance of multiple cell types across a wide range of organisms.
Eduardo Leyva-Díaz
doaj +2 more sources
The Role of NKL Homeobox Genes in T-Cell Malignancies [PDF]
Biomedicines, 2021 Homeobox genes encode transcription factors controlling basic developmental processes. The homeodomain is encoded by the homeobox and mediates sequence-specific DNA binding and interaction with cofactors, thus operating as a basic regulatory platform ...
Stefan Nagel
doaj +2 more sources
Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification [PDF]
PLoS Genetics, 2022 Homeobox genes are prominent regulators of neuronal identity, but the extent to which their function has been probed in animal nervous systems remains limited.
Molly B. Reilly +18 more
doaj +3 more sources
Homeobox Genes and Hepatocellular Carcinoma. [PDF]
Cancers (Basel), 2019 Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, and is the third leading cause of cancer-related deaths each year. It involves a multi-step progression and is strongly associated with chronic inflammation induced by the intake of environmental toxins and/or viral infections (i.e., hepatitis B and C viruses).
Liu KY, Wang LT, Hsu SH, Wang SN.
europepmc +4 more sources
The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects [PDF]
Frontiers in Physiology, 2020 Vasculogenesis and angiogenesis are key processes of placental development, which occur throughout pregnancy. Placental vasculogenesis occurs during the first trimester of pregnancy culminating in the formation of hemangioblasts from intra-villous stem ...
Nadia Alfaidy +12 more
doaj +2 more sources
A TALE of shrimps: Genome-wide survey of homeobox genes in 120 species from diverse crustacean taxa [version 1; referees: 2 approved, 1 approved with reservations] [PDF]
F1000Research, 2018 The homeodomain-containing proteins are an important group of transcription factors found in most eukaryotes including animals, plants and fungi. Homeobox genes are responsible for a wide range of critical developmental and physiological processes ...
Wai Hoong Chang, Alvina G. Lai
doaj +2 more sources
Role of Homeobox Genes in Tooth Morphogenesis: A Review [PDF]
Journal of Clinical and Diagnostic Research, 2015 In oral cavity, disturbances due to genetic alterations may range from lack of tooth development to morphological defects. Due to technical advances in genetic engineering and molecular biology, valuable information regarding dentofacial growth could be
Sreevalli Suryadeva +1 more
doaj +2 more sources
Endocrine Regulations, 2023 Objective. Homeobox genes play a fundamental role in the embryogenesis, but some of them have been linked to oncogenesis. The present study is aimed to investigate the impact of glucose and glutamine deprivations on the expression of homeobox genes such ...
Krasnytska Dariia O. +8 more
doaj +1 more source
Hemato, 2022 Homeobox genes encode transcription factors which control basic processes in development and differentiation. Concerning the sequence conservation in their homeobox, these genes are arranged into particular groups sharing evolutionary ancestry and ...
Stefan Nagel
doaj +1 more source
The Homeobox Genes of Caenorhabditis elegans and Insights into Their Spatio-Temporal Expression Dynamics during Embryogenesis. [PDF]
PLoS ONE, 2015 Homeobox genes play crucial roles for the development of multicellular eukaryotes. We have generated a revised list of all homeobox genes for Caenorhabditis elegans and provide a nomenclature for the previously unnamed ones.
Jürgen Hench +10 more
doaj +1 more source