BMC Genomics, 2020 Background Homeobox-containing genes encode crucial transcription factors involved in animal, plant and fungal development, and changes to homeobox genes have been linked to the evolution of novel body plans and morphologies.
Yiqian Li +7 more
doaj +1 more source
The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development [PDF]
, 1998 Hox11 is a homeobox gene essential for spleen formation in mice, since atrophy of the anlage of a developing spleen occurs in early embryonic development in Hox11 null mice.
Greene, W.K. +3 more
core +2 more sources
Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]
, 2019 This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia +11 more
core +1 more source
Congenital absence of the left thumb in a surviving twin - a genetic disorder
National Journal of Clinical Anatomy, 2014 Congenital absence of left thumb with deformities of carpal bones in a twin born adult woman is reported here. The subject is the only surviving twin aged forty years reported to the hospital with a complaint of weakness of left hand.
D N Sinha
doaj +1 more source
Predictability of hand skill and cognitive abilities from craniofacial width in right- and left-handed men and women: relation of skeletal structure to cerebral function [PDF]
, 2002 Recently, a family of homeobox genes involved in brain and craniofacial development was identified. In light of this genetic background, we hypothesized that some functional characteristics of human brain (hand skill, cognition) may be linked to some ...
Dayi, Ertunc +2 more
core +1 more source
Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate. [PDF]
PLoS ONE, 2012 Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development.
Heike Hadrys +6 more
doaj +1 more source
Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]
, 2011 The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Alexander Thompson +10 more
core +1 more source
Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.
PLoS ONE, 2021 Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation and are grouped into classes and subclasses according to sequence similarities.
Stefan Nagel +4 more
doaj +1 more source
The molecular basis of T cell acute lymphoblastic leukemia [PDF]
, 2012 T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando +23 more
core +1 more source
NKL homeobox genes in leukemia [PDF]
Leukemia, 2011 NK-like (NKL) homeobox genes code for transcription factors, which can act as key regulators in fundamental cellular processes. NKL genes have been implicated in divergent types of cancer. In this review, we summarize the involvement of NKL genes in cancer and leukemia in particular.
Homminga, Irene +2 more
openaire +4 more sources