Sap transporter mediated import and subsequent degradation of antimicrobial peptides in Haemophilus. [PDF]
PLoS Pathogens, 2011 Antimicrobial peptides (AMPs) contribute to host innate immune defense and are a critical component to control bacterial infection. Nontypeable Haemophilus influenzae (NTHI) is a commensal inhabitant of the human nasopharyngeal mucosa, yet is commonly ...
Catherine L Shelton +4 more
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Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]
, 2014 Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna +56 more
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Tissue expression and developmental regulation of chicken cathelicidin antimicrobial peptides
Journal of Animal Science and Biotechnology, 2012 Cathelicidins are a major family of antimicrobial peptides present in vertebrate animals with potent microbicidal and immunomodulatory activities. Four cathelicidins, namely fowlicidins 1 to 3 and cathelicidin B1, have been identified in chickens.
Achanta Mallika +5 more
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Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]
, 2017 Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín +1 more
core +1 more source
Host Defense Peptides in Wound Healing
Molecular Medicine, 2008 Host defense peptides are effector molecules of the innate immune system. They show broad antimicrobial action against gram-positive and -negative bacteria, and they likely play a key role in activating and mediating the innate as well as adaptive immune response in infection and inflammation. These features make them of high interest for wound healing
Lars, Steinstraesser +9 more
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Defensins: antifungal lessons from eukaryotes
Frontiers in Microbiology, 2014 Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research towards the finding of a viable alternative to current antifungal drugs.
Patrícia M. Silva +2 more
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In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection [PDF]
, 2017 Pseudomonas aeruginosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers. Recently, the frog skin-derived antimicrobial peptide (AMP) Esc(1-21) and its diastereomer Esc(1-21)-1c were found to ...
Chen, Chen +2 more
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Multifunctional host defense peptides: antiparasitic activities [PDF]
The FEBS Journal, 2009 Whereas significant knowledge is accumulating on the antibacterial and antifungal properties of host defense peptides (HDPs) and their synthetic mimics, much less is known of their activities against parasites. A variety of in vitro and in vivo antiparasitic assays suggest that these notorious antimicrobial compounds could represent a powerful tool for
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Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. [PDF]
, 2020 Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish panels of serum protein biomarkers representative of active TB patients and their household contacts who were either infected (LTBI)
Anibarro, L +11 more
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Dietary Nutrients Mediate Intestinal Host Defense Peptide Expression [PDF]
Advances in Nutrition, 2020 The intestinal tract is the shared locus of intestinal epithelial cells, immune cells, nutrient digestion and absorption, and microbial survival. The gut in animals faces continuous challenges in communicating with the external environment. Threats from endogenous imbalance and exogenous feeds, especially pathogens, could trigger a disorder of ...
Jianmin Wu +3 more
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