Results 51 to 60 of about 2,543,243 (267)
Frontiers in Microbiology, 2011 In the last few years, the number of bacteria with enhanced resistance to conventional antibiotics has dramatically increased. Most of such bacteria belong to regular microbial flora, becoming a real challenge, especially for immune-depressed patients ...
Osmar Nascimento Silva +7 more
doaj +1 more source
Host-defense peptides: from biology to therapeutic strategies
, 2011 Primitive innate defense mechanisms in the form of gene-encoded antimicrobial peptides are now considered as potential candidates for the development of new therapeutics.
Maria Luisa Mangoni +1 more
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
New horizons for host defense peptides and lantibiotics [PDF]
Current Opinion in Pharmacology, 2012 Antimicrobial peptides from either microbial sources, or based on host defense peptides (HDPs) from higher organisms, show promising activity against human pathogens. Lantibiotics have been extensively engineered by either molecular biology approaches or chemistry and both natural and modified entities have been shown to have good efficacy in animal ...
Michael John, Dawson, Richard W, Scott
openaire +2 more sources
PepBio: predicting the bioactivity of host defense peptides
, 2017 A large-scale QSAR study of host defense peptides sheds light on the origin of their bioactivities (antibacterial, anticancer, antiviral and antifungal).
Hao Li +21 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Primer sequences of porcine host defense peptides for real time PCR.
, 2013 Primer sequences of porcine host defense peptides for real time PCR.
Megan Bible (452368) +7 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Optimizing Antimicrobial Host Defense Peptides
Chemistry & Biology, 2006 Antimicrobial host defense peptides constitute a major component of innate immune systems. Expectations are high to develop them into a novel class of anti-infective agents. In this issue of Chemistry & Biology, Hilpert et al. describe new design and peptide synthesis strategies for systematically investigating such concepts.
openaire +2 more sources
Characterization of genes coding for small hypervariable peptides in Globodera rostochiensis [PDF]
, 2008 Plant parasitic nematodes secrete a cocktail of effector molecules, which are involved in several aspects of the interaction with the host, eg. in host defense suppression, in migration and in feeding cell formation.
Bers, N.E.M., van
core