Results 51 to 60 of about 7,043,725 (272)

Identification of promising host-induced silencing targets among genes preferentially transcribed in haustoria of Puccinia [PDF]

BMC Genomics, 2015
The cereal rust fungi are destructive pathogens that affect grain production worldwide. Although the genomic and transcript sequences for three Puccinia species that attack wheat have been released, the functions of large repertories of genes from Puccinia still need to be addressed to understand the infection process of these obligate parasites.
Yin, Chuntao, Downey, Samantha I, Klages-Mundt, Naeh L, Ramachandran, Sowmya, Chen, Xianming, Szabo, Les J, Pumphrey, Michael, Hulbert, Scot H   +7 more
openaire   +3 more sources

RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA [PDF]

Open Biology, 2015
MicroRNAs (miRNAs) integrate with Argonaut (Ago) to create the RNA-induced silencing complex, and regulate gene expression by silencing target mRNAs. RNA editing of miRNA may affect miRNA processing, assembly of the Ago complex and target mRNA binding ...
Yalei Cui, Tianzhi Huang, Xiaobo Zhang   +2 more
doaj   +1 more source

RNA interference in Thysanoptera: mechanism, applications, and risk assessment

Green Chemistry Letters and Reviews
Thysanoptera, commonly known as thrips, are agricultural pests capable of causing significant crop damage and serving as vectors for plant viruses. RNA interference (RNAi) has been widely studied as a potential approach for pest management due to its ...
Lin Tian, Yixuan Zhang, Li He, Yanna Huang, Xueming Tang   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Virus-Induced Gene Silencing of Cell Wall Genes in Flax (Linum usitatissimum)

, 2020
International audiencePlants have developed defense mechanisms against viruses by using an RNA silencing-based process, which has many common features with the endogenous RNA silencing pathway used for regulating the level of transcripts derived from ...
Godfrey Neutelings, Neutelings, Godfrey,, Maxime Chantreau, Neutelings, Godfrey, G., Chantreau, Maxime, Chantreau, Maxime,   +5 more
core   +1 more source

Nanotechnology-enabled dsRNA-based product development for crop protection

Plant Nano Biology
Double-stranded RNA (dsRNA) crop protection is advancing through two distinct product routes: transformative approaches, including host-induced gene silencing (HIGS) and plastid-expressed dsRNA, and non-transformative approaches, including spray-induced ...
Ulhas S. Kadam, Jong Chan Hong
doaj   +1 more source

Extracellular vesicles isolated from dsRNA-sprayed barley plants exhibit no growth inhibition or gene silencing in Fusarium graminearum

Fungal Biology and Biotechnology, 2022
Numerous reports have shown that incorporating a double-stranded RNA (dsRNA)-expressing transgene into plants or applying dsRNA by spraying it onto their leaves successfully protects them against invading pathogens exploiting the mechanism of RNA ...
Timo Schlemmer, Richard Lischka, Linus Wegner, Katrin Ehlers, Dagmar Biedenkopf, Aline Koch   +5 more
doaj   +1 more source

HIGS: Host-Induced Gene Silencing in the Obligate Biotrophic Fungal Pathogen Blumeria graminis     [PDF]

The Plant Cell, 2010
Abstract Powdery mildew fungi are obligate biotrophic pathogens that only grow on living hosts and cause damage in thousands of plant species. Despite their agronomical importance, little direct functional evidence for genes of pathogenicity and virulence is currently available because mutagenesis and transformation protocols are ...
Daniela, Nowara, Alexandra, Gay, Christophe, Lacomme, Jane, Shaw, Christopher, Ridout, Dimitar, Douchkov, Götz, Hensel, Jochen, Kumlehn, Patrick, Schweizer   +8 more
openaire   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source