Results 51 to 60 of about 924,399 (169)

Rational Design of Multicomponent Polymeric Systems Based on a Transient Plasticization Window for Hot-Melt Extrusion

Pharmaceutics
Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by elevated thermal and shear stresses that may induce degradation of thermolabile active pharmaceutical ...
Mark Mandrik, Veronika Makarova, Ludmila Korol, Ivan Krasnyuk, Sergey Antonov   +4 more
doaj   +1 more source

Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

Pharmaceutics, 2018
The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone ...
Ludmila A. G. Pinho, Saulo G. Souza, Ricardo N. Marreto, Livia L. Sa-Barreto, Tais Gratieri, Guilherme M. Gelfuso, Marcilio Cunha-Filho   +6 more
doaj   +1 more source

Comparative Functionality and Processing of Plant‐Proteins: A Path Toward Optimized Sustainable Plant‐Based Meat Analogues (PBMAs): A Review

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
The review provides a comprehensive comparison in terms comparison of commercially established and emerging plant protein sources, focusing on their structural, rheological, and sensory attributes for developing sustainable plant‐based meat analogues (PBMAs).
Mian N. Riaz, Fariha Irshad, Muhammad Bilal Haider, Debomitra Dey   +3 more
wiley   +1 more source

Formulation of topical ibuprofen solid lipid nanoparticle (SLN) gel using hot melt extrusion technique (HME) and determining its anti-inflammatory strength

Drug Delivery and Translational Research, 2019
Solid lipid nanoparticles (SLN) have been formulated using various batch processes, e.g., solvent diffusion evaporation, emulsification solvent evaporation followed by size reduction using high-pressure homogenization (HPH) or ultrasonication. However, for the manufacturing of formulations, continuous processes are always preferred over batch processes
Bagde, Arvind, Patel, Ketan, Kutlehria, Shallu, Chowdhury, Nusrat, Singh, Mandip   +4 more
openaire   +2 more sources

A Scale‐Up Study on the Continuous Production of Battery Slurry in Twin‐Screw Extruders Based on Flow Behavior and Material Dispersion

Energy Technology, Volume 14, Issue 3, March 2026.
This study shows how anode‐slurry quality can be reliably transferred from laboratory to pilot and production scales in twin‐screw extrusion. By combining experiments with flow simulations, the authors identify key scale‐up criteria that govern dispersion of conductive additives. The work also clarifies how process parameters influence slurry structure,
Juan Fernando Meza Gonzalez, Annika Völp, Hermann Nirschl, Frank Rhein   +3 more
wiley   +1 more source

Process induced degradation of carbamazepine during hot melt extrusion

British Journal of Pharmacy, 2023
The aim of this study was to evaluate hot melt extrudates of carbamazepine (CBZ) for presence of process induced degradation product iminostilbene (IMB) and quantifying using high performance liquid chromatography (HPLC). CBZ was used as model drug.
Sarbamangala Bose, Anant Paradkar, Adrian Kelly, Harika Magam   +3 more
doaj   +1 more source

Unlocking the Potential of Adzuki Bean: A Sustainable Red Protein With Techno‐Functional and Antioxidant Properties for Plant‐Based Meat

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
Systematic evaluation of sustainable adzuki bean protein extraction revealed a multi‐functional ingredient with nutritional, antioxidant, and techno‐functional properties, enabling its direct use in a clean‐label jerky style prototype delivering a comparable protein level to meat jerky but with reduced sodium, sugar, cholesterol, at high dietary fiber ...
Gomathy Sandhya Subramanian, Jordy Ling, Ryan Soh, Qinghao Ning, Xin Yi See, Shu Mei Man, Jin Wen Aw, Keng Guan Lim, Daryl Lee, Sergey Gorelik, Rong Ying Megan Teo, Yoganathan Kanagasundaram, Siew Bee Ng, Khin Yin Win, Maria N. Antipina   +14 more
wiley   +1 more source

Optimization of Amorphization Kinetics during Hot Melt Extrusion by Particle Engineering: An Experimental and Computational Study

, 2021
Hot melt extrusion (HME) to prepare amorphous solid dispersions (ASDs) at temperatures below the drug’s melting point requires the crystalline drug to dissolve into the molten polymer. This requires an understanding of the drug’s solubility in the molten
Mingyue Li (1582399), Yongchao Su, Isaac D. Corum (11841834), Zoltan K. Nagy (1515985), Mingyue Li, Ayse Eren (11841828), Ayse Eren, Dana E. Moseson (6654068), Lynne S. Taylor, Dana E. Moseson, Kevin J. Altman, Zoltan K. Nagy, Isaac D. Corum, Kevin J. Altman (11841831), Lynne S. Taylor (1349709), Yongchao Su (1317195)   +15 more
core   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Innovations in food extrusion technologies: Applications, advances, and future prospects-a review

Applied Food Research
Innovations in food extrusion technologies have significantly expanded their applications beyond traditional processing, encompassing personalized nutrition, targeted bioactive delivery, and sustainable packaging solutions. This review highlights cutting-
Muhammad Asif, Sammra Maqsood, Saria Yousaf, Muhammad Imran, Elahesadat Hosseini, Leila Nateghi   +5 more
doaj   +1 more source