Results 91 to 100 of about 13,686 (217)
Food Frontiers, Volume 7, Issue 5, September 2026.Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
HSF1 transcriptional activity is modulated by IER5 and PP2A/B55 [PDF]
, 2015 Heat shock factor 1 (HSF1) is the master transcriptional regulator of chaperone genes. HSF1 regulates the expression of the immediate-early response gene IER5, which encodes a protein that has roles in the stress response and cell proliferation. Here, we
Kawabata, Shotaro +2 more
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Serum HSF1 is upregulated in endometriosis patients and serves as a potential diagnostic biomarker
Kaohsiung Journal of Medical Sciences, 2023 Endometriosis (EMS) is a prevalent gynecological condition lacking reliable diagnostic biomarkers. This prospective study aimed to analyze the potential of serum heat shock transcription factor 1 (HSF1) as a diagnostic marker for EMS.
Hui‐Ying Pan, Jing Wan
doaj +1 more source
Legume Science, Volume 8, Issue 3, September 2026.ABSTRACT Soybean (Glycine max L.) is the world's most important oilseed crop, supplying 25% of world‘s edible oil and 66% of feed protein. This review address genomic innovations to overcome yield constraints and climate vulnerability (especially drought stress) in high‐oil soybean breeding.
Mujeeb Ur Rehman +7 more
wiley +1 more source
GSK3 represses HSF1 activity in yeast independent of S303. [PDF]
, 2013 (A) PS145 (WT) expressing wild-type HSF1 or the S303A HSF1 mutant and LNY1 (rim11Δ) expressing wild-type HSF1 were grown in dextrose supplemented medium for 4 d. Growth was monitored by measuring O.D.600.
Claudina Rodrigues-Pousada (164208) +4 more
core +1 more source
MedComm, Volume 7, Issue 9, September 2026.This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng +9 more
wiley +1 more source
Regulation of Hsf1 by stress response crosstalk in Saccharomyces cerevisiae [PDF]
, 2021 Heat shock factor 1 (Hsf1) is a conserved transcription factor involved in cellular response to folding stress. A simple model has been proposed in which Hsf1 monitors misfolded protein species through a negative feedback loop.
Kane, Andrew
core
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.Selenium nanoparticles (SeNPs) outperform sodium selenite in raising serum selenium levels and suppressing HSP60, HSP70, and HSP90 transcription in periparturient goats and their offspring, indicating reduced cellular stress regardless of cloning status.
Gholam‐Ali Kojouri +2 more
wiley +1 more source
Effects of LRP1B Regulated by HSF1 on Lipid Metabolism in Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2020 Miaomiao Li,1,* Juntao Hu,2,* Riming Jin,3,* Hongxia Cheng,1 Huaping Chen,4 Limin Li,4 Kun Guo1 1Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People ...
Li M +6 more
doaj
Current Challenges of Transcription Compartmentalization Research
Advanced Science, Volume 13, Issue 46, 17 August 2026.Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley +1 more source