Results 191 to 200 of about 20,857 (230)

UBAP2L-driven stress granule formation links oxaliplatin resistance to gastric cancer. [PDF]

Commun Biol
Wu C, Yan Y, Chen Q, Lian Z, He J, Ling R, Lei X, Peng Y, Zheng B, Yang Q, Ye G, Ma W, Li G.   +12 more
europepmc   +1 more source

The role of circadian rhythm-related genes in type 2 diabetes from a multi-omics perspective. [PDF]

J Glob Health
Xie L, Huang D, Zha X, Wei C, Dong J, Zheng H, Xu Z, Wu J, Lai P.   +8 more
europepmc   +1 more source

Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes. [PDF]

EMBO J
Malfait J, Wan J, Singh HN, Souaid C, Farah G, Su J, Torres M, Manosalva I, Sakakini N, Esnault C, Sarrazin S, Sieweke M, Spicuglia S.   +12 more
europepmc   +1 more source

HSF1: Guardian of Proteostasis in Cancer [PDF]

Trends in Cell Biology, 2016
Proteomic instability is causally related to human diseases. In guarding proteome stability, the heat shock factor 1 (HSF1)-mediated proteotoxic stress response plays a pivotal role. Contrasting with its beneficial role of enhancing cell survival, recent findings have revealed a compelling pro-oncogenic role for HSF1. However, the mechanisms underlying
Chengkai Dai
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

HSF1, Aging, and Neurodegeneration

2022
Heat shock factor 1 (HSF1) is a master transcription regulator that mediates the induction of heat shock protein chaperones for quality control (QC) of the proteome and maintenance of proteostasis as a protective mechanism in response to stress.
Alice Y, Liu, Conceição A, Minetti, David P, Remeta, Kenneth J, Breslauer, Kuang Yu, Chen   +4 more
openaire   +2 more sources

Trans-HSF1 Express

Science, 2013
Ribosome activity is linked to the activity of a transcription factor in cancer cells. [Also see Research Article by Santagata et al. ]
Valentina Gandin, Ivan Topisirovic
openaire   +1 more source

Rethinking HSF1 in Stress, Development, and Organismal Health [PDF]

Trends in Cell Biology, 2017
The heat shock response (HSR) was originally discovered as a transcriptional response to elevated temperature shock and led to the identification of heat shock proteins and heat shock factor 1 (HSF1). Since then HSF1 has been shown to be important for combating other forms of environmental perturbations as well as genetic variations that cause ...
Jian Li, Richard I Morimoto, Johnathan Labbadia   +2 more
exaly   +4 more sources

HSF1 as a Mitotic Regulator: Phosphorylation of HSF1 by Plk1 Is Essential for Mitotic Progression

Cancer Research, 2008
Abstract Previously, heat shock factor 1 (HSF1) had been reported to induce genomic instability and aneuploidy by interaction with Cdc20. Here, we have further examined the functions of HSF1 in the regulation of mitosis. A null mutant or knockdown of HSF1 caused defective mitotic progression. By monitoring chromosomes in living cells,
Yoon-Jin, Lee, Eun-Ho, Kim, Jae Seon, Lee, Dooil, Jeoung, Sangwoo, Bae, Seung Hae, Kwon, Yun-Sil, Lee   +6 more
openaire   +2 more sources

Maternal effect of Hsf1 on reproductive success

Nature, 2000
A protein known as heat-shock factor-1 (HSF1) is a major transactivator of stress-inducible genes in response to environmental changes, but it is also implicated in extra-embryonic development and female fertility in mice1,2. Here we show that mouse embryos whose mothers lack this protein are unable to develop properly beyond the zygotic stage ...
E, Christians, A A, Davis, S D, Thomas, I J, Benjamin   +3 more
exaly   +3 more sources