Results 31 to 40 of about 13,686 (217)
HSF1 and GAPDH Western Blot [PDF]
Western blot data for HSF1 and GAPDH. Blot using chemiluminescence to show HSF1 and GAPDH.Blot using bright field to show ladder.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Holman, A (via Mendeley Data)
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Protein kinase A binds and activates heat shock factor 1. [PDF]
Many inducible transcription factors are regulated through batteries of posttranslational modifications that couple their activity to inducing stimuli.
Ayesha Murshid +5 more
doaj +1 more source
HSF1 aptamer inhibits mitogenic signaling. [PDF]
(A) HSF1 inhibition attenuates EGF receptor activation following the addition of EGF to HeLa cells. (B) HSF1 inhibition by iaRNAHSF1 causes a depletion of the total levels and activated forms of Erk1/2.
Richard A. Cerione (464912) +4 more
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FCS analysis of HSF1 -K80Q in immortalized MEFs form HSF1 null mice. [PDF]
Dynamics of HSF1- K80Q-eGFP and WT HSF1-eGFP before (NHS, blue) and after 30 minutes heat shock (HS, red) in immortalized MEFs from HSF1 null mice.
Antoine Delon (431449) +7 more
core +1 more source
Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
Heat shock factor (Hsf1) regulates the expression of molecular chaperones to maintain protein homeostasis. Despite its central role in stress resistance, disease and aging, the mechanisms that control Hsf1 activity remain unresolved. Here we show that in
Xu Zheng +6 more
doaj +1 more source
Pleiotropic Role of HSF1 in Neoplastic Transformation [PDF]
HSF1 (Heat Shock transcription Factor 1) is the main transcription factor activated in response to proteotoxic stress. Once activated, it induces an expression of heat shock proteins (HSPs) which enables cells to survive in suboptimal conditions. HSF1 could be also activated by altered kinase signaling characteristic for cancer cells, which is a ...
Vydra, Natalia +2 more
openaire +2 more sources
mFCS analysis of HSF1 -K80Q in cells knocked-down for endogenous HSF1. [PDF]
Dynamics of HSF1- K80Q-eGFP before (NHS, blue) and after a one hour heat shock (HS, red), in cells knocked-down for endogenous HSF1. mFCS acquisitions were made, 24 hours after two rounds of treatment with a siRNA against endogenous HSF1, followed by ...
Antoine Delon (431449) +7 more
core +1 more source
The Multifaceted Role of HSF1 in Tumorigenesis
Heat Shock Factor 1 (HSF1), the master transcriptional regulator of the heat shock response (HSR), was first cloned more than 30 years ago. Most early research interrogating the role that HSF1 plays in biology focused on its cytoprotective functions, as a factor that promotes the survival of organisms by protecting against the proteotoxicity associated
Milad J, Alasady, Marc L, Mendillo
openaire +3 more sources
Summary: Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essential ...
Xi Ling +9 more
doaj +1 more source
S303 phosphorylation represses HSF1 activity in yeast. [PDF]
(A) PS145 yeast strains expressing wild-type HSF1 (WT) or the S303A, S307A or S303/307A mutants were plated on either galactose or dextrose supplemented medium.
Claudina Rodrigues-Pousada (164208) +4 more
core +1 more source

