Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. [PDF]
PLoS Pathogens, 2012 Thermal adaptation is essential in all organisms. In yeasts, the heat shock response is commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased genetic screens with directed molecular dissection to demonstrate that ...
Michelle D Leach +5 more
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Phosphoglycerate kinase 1 (PGK1); heat shock protein 90 (Hsp90) [PDF]
Science-Business eXchange, 2014 openalex +2 more sources
Plasmodium falciparum heat shock protein 90 (PF14_0417; hsp90) [PDF]
Science-Business eXchange, 2010 openalex +3 more sources
Changes in HSP gene and protein expression in natural scrapie with brain damage [PDF]
Veterinary Research, 2011 Heat shock proteins (Hsp) perform cytoprotective functions such as apoptosis regulation and inflammatory response control. These proteins can also be secreted to the extracellular medium, acting as inflammatory mediators, and their chaperone activity ...
Serrano Carmen +11 more
doaj +3 more sources
Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.
Proceedings of the National Academy of Sciences of the United States of America, 1986 Shigeo Koyasu +8 more
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Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
Pharmaceutics, 2021 Heat shock protein 90 (Hsp90) is a chaperone responsible for the maturation of many cancer-related proteins, and is therefore an important target for the design of new anticancer agents.
Jaka Dernovšek +6 more
doaj +1 more source
Anaplastic lymphoma kinase (ALK); heat shock protein 90 (Hsp90) [PDF]
Science-Business eXchange, 2011 openalex +3 more sources
The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. [PDF]
PLoS ONE, 2013 The heat shock response (HSR) is a highly conserved molecular response to various types of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to prevent and repair damages in labile proteins and membranes.
Zohar Bromberg +3 more
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Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
MedComm, 2022 The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect cells from stresses.
Chen Hu +9 more
semanticscholar +1 more source
Medicinal research reviews (Print), 2020 Heat shock proteins (Hsps) are molecular chaperones that also play important roles in the activation of the heat shock response (HSR). The HSR is an evolutionary conserved and protective mechanism that is used to counter abnormal physiological conditions,
S. Chaudhury, Bradley M Keegan, B. Blagg
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