Results 21 to 30 of about 109,486 (229)
Viruses, 2020 Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Amanda M. Casto +6 more
doaj +1 more source
Herpes simplex virus-type1 (HSV-1) impairs DNA repair in cortical neurons [PDF]
, 2016 Several findings suggest that Herpes simplex virus-1 (HSV-1) infection plays a role in the neurodegenerative processes that characterize Alzheimer's disease (AD), but the underlying mechanisms have yet to be fully elucidated.
Alessio Cardinale +12 more
core +2 more sources
Herpes Simplex Virus Type-2 Paralyzes the Function of Monocyte-Derived Dendritic Cells
Viruses, 2020 Herpes simplex viruses not only infect a variety of different cell types, including dendritic cells (DCs), but also modulate important cellular functions in benefit of the virus. Given the relevance of directed immune cell migration during the initiation
Linda Grosche +7 more
doaj +1 more source
Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells [PDF]
, 2016 We have previously shown that clusters of guanine quadruplex (G4) structures can form in the human herpes simplex-1 (HSV-1) genome. Here we used immunofluorescence and immune-electron microscopy with a G4-specific monoclonal antibody to visualize G4 ...
Artusi, Sara +6 more
core +1 more source
Revista de Saúde Pública, 2010 OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2) e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população ...
Sue Ann Costa Clemens +1 more
doaj +1 more source
Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation [PDF]
, 2015 Increasing evidence suggests that recurrent Herpes Simplex Virus type 1 (HSV-1) infection spreading to the CNS is a risk factor for Alzheimer's Disease (AD) but the underlying mechanisms have not been fully elucidated yet.
De Chiara, Giovanna +7 more
core +2 more sources
MORC3, a component of PML nuclear bodies, has a role in restricting herpes simplex virus type 1 and human cytomegalovirus [PDF]
, 2016 We previously reported that MORC3, a protein associated with promyelocytic leukemia nuclear bodies (PML NBs), is a target of HSV-1 ICP0 mediated degradation.
Everett, Roger +2 more
core +1 more source
Journal of Ophthalmic & Vision Research, 2020 Purpose: To describe and analyze the microstructural changes in herpetic stromal keratitis (HSK) observed in vivo by spectral-domain ocular coherence tomography (SD-OCT) at different stages of the disease.
Alejandro Rodriguez-Garcia +3 more
doaj +1 more source
Viruses, 2023 HSV-1 disease is a significant public health burden causing orofacial, genital, cornea, and brain infection. We previously reported that a trivalent HSV-2 gC2, gD2, gE2 nucleoside-modified mRNA-lipid nanoparticle (LNP) vaccine provides excellent ...
Kevin P. Egan +10 more
doaj +1 more source
Understanding HSV‐1 entry glycoproteins [PDF]
Reviews in Medical Virology, 2007 AbstractHerpes Simplex Virus‐1 is a common infectious agent, but the precise detail of entry and infection of cells has only now begun to be clarified. Four viral surface glycoproteins (gB, gD, gH and gL) are required. This review summarises the known structure and function of each of these essential viral envelope glycoproteins, and explores what is ...
Gabriele Pollara +4 more
openaire +3 more sources