Results 51 to 60 of about 83,455 (287)
EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets
Advanced Science, EarlyView.Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang +4 more
wiley +1 more source
Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran [PDF]
Iranian Journal of Public Health, 2012 Background: Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran.
S Rezaei-Chaparpordi +7 more
doaj +2 more sources
Herpes Simplex Virus 1 Tegument Protein UL46 Inhibits TANK-Binding Kinase 1-Mediated Signaling
mBio, 2019 TANK-binding kinase 1 (TBK1) is a key component of the antiviral immunity signaling pathway. It activates downstream interferon regulatory factor 3 (IRF3) and subsequent type I interferon (IFN-I) production.
Hongjuan You +5 more
doaj +1 more source
Marine Drugs, 2020 The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities.
Natalya V. Krylova +10 more
doaj +1 more source
Advanced Science, EarlyView.Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej +10 more
wiley +1 more source
Negative epidemiological association between HSV-1 and HSV-2 infections
Heliyon, 2019 Objectives: Existing evidence on an epidemiological association between herpes simplex virus (HSV) type 1 and type 2 infections remains conflicting and inconclusive.
Gheyath K. Nasrallah +2 more
doaj +1 more source
Seroprevalence of Herpes Simplex Virus Type 1 and 2 in Taiwan and Risk Factor Analysis, 2007. [PDF]
PLoS ONE, 2015 Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) are common human pathogens and might cause severe illness. Following primary infection, the viruses establish lifelong latent infection and are transmitted by close contact, both sexual and nonsexual ...
Jen-Hsiang Shen +5 more
doaj +1 more source
1065 A replication-defective, HSV-1-based gene therapy for localized delivery of combinatorial Interleukins-12 and -2 for the treatment of cutaneous malignancies [PDF]
, 2023 Dana M. Previte +4 more
openalex +1 more source
Neonatal Genital HSV-1 After Jewish Circumcision [PDF]
Clinical Pediatrics, 2016 Neonatal herpes simplex virus (HSV) infection incidence has increased in the past decade to 8 to 60 per 100 000 live births in the United States.1 In Israel, the current incidence is estimated to be 8.4 per 100 000 live births2. In 85% of the cases, the infection is transmitted vertically during the passage in the birth canal, the minority of the cases
Tzvi-Behr, Shimrit +3 more
openaire +2 more sources
Advanced Science, EarlyView.A defect‐engineered assembly strategy is reported for the in situ encapsulation of acetylcholinesterase (AChE) into amorphous MOF‐74, endowing the composite with superior catalytic activity and target recognition capability. Leveraging these structural advantages, a sensitive and stable biosensor is constructed for the detection of paraoxon pesticide ...
Changshun Su +7 more
wiley +1 more source