Assessment of Human Epididymis Protein 4 Expression in Breast Ductal Carcinoma In Situ [PDF]
DiagnosticsBackground/Objectives: Elevated expression of human epididymis protein 4 (HE4) has been observed in breast cancer and is associated with cancer progression; however, its role in ductal carcinoma in situ (DCIS) remains unclear.
Nah Ihm Kim, Min Ho Park, Ji Shin Lee
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Prognostic Value of Human Epididymis Protein 4 in Acute Myocardial Infarction [PDF]
International Journal of General MedicineYi Tang,1,* Wen-Yu Zhu,2,* Si-Ling Peng,2,* Shuai Huang,2,* Qiu-Ni Zhao,3 Si-Yuan Tan,2 Zi-Hui Yin,2 Yan Zhang,1 Jian-Qiang Peng,1 Hong-Wei Pan1 1Department of Cardiology, Hunan Provincial People’s Hospital, The First Affiliated Hospital ...
Tang Y +9 more
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Human epididymis protein 4-annexin II binding promotes aberrant epithelial-fibroblast crosstalk in pulmonary fibrosis [PDF]
Communications BiologyInvasive lung myofibroblasts are the main cause of tissue remodeling in idiopathic pulmonary fibrosis (IPF). A key mechanism contributing to this important feature is aberrant crosstalk between the abnormal/injured lung epithelium and pulmonary ...
Weishuai Zheng +7 more
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Elevated serum levels of human epididymis protein 4 in adult patients with proliferative lupus nephritis [PDF]
Frontiers in Immunology, 2023 BackgroundThis study aimed to access whether serum human epididymis protein 4 (HE4) level could identify lupus nephritis (LN) pathological classes in adults and children.MethodsThe serum HE4 levels of 190 healthy subjects and 182 patients with systemic ...
Liubing Li +11 more
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Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer [PDF]
The Clinical Respiratory JournalObjective This study aimed to explore the application value of human epididymis protein 4 (HE4) in diagnosing and monitoring the prognosis of lung cancer.
Tingting Zhang +4 more
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Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease [PDF]
Respiratory Research, 2022 Background Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by chronic inflammation and airway remodeling. Human epididymis protein 4 (HE4) plays a critical role in various inflammatory or fibrotic diseases.
Yuan Zhan +10 more
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Diagnostic value of cerebrospinal fluid human epididymis protein 4 for leptomeningeal metastasis in lung adenocarcinoma [PDF]
Frontiers in ImmunologyBackgroundThe diagnosis of lung adenocarcinoma (LUAD) leptomeningeal metastasis (LM) remains a clinical challenge. Human epididymis protein 4 (HE4) functions as a novel tumor biomarker for cancers.
Xiangyu Li +5 more
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Nomogram using human epididymis protein 4 predicted concurrent endometrial cancer from endometrial atypical hyperplasia before surgery [PDF]
Frontiers in OncologyObjectiveTo establish a nomogram based on presurgical predictors of concurrent endometrial cancer (EC) for patients diagnosed with endometrial atypical hyperplasia before definitive surgery (preoperative-EAH) to improve the risk stratification and ...
Yaochen Lou +3 more
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Elevated level of serum human epididymis protein 4 (HE4) predicts disease severity and mortality in COVID-19 pneumonia [PDF]
BMC Pulmonary Medicine, 2023 Background We retrospectively analyzed serum level of human epididymis protein 4 (HE4) as a pulmonary inflammatory biomarker in patients with COVID-19 pneumonia in association with disease severity and outcome.
Renáta Sütő +10 more
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Evaluation of follow-up observation using human epididymis protein 4, a tumor marker, in patients with ovarian cancer [PDF]
Obstetrics & Gynecology Science, 2023 Objective We evaluated the usefulness of human epididymis protein 4 (HE4), a tumor marker, during and after treatment in patients with ovarian cancer (OC).
Masaya Uno +3 more
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