Results 61 to 70 of about 192,493 (241)
Clinical Usefulness of Human Epididymis Protein 4 in Lung Cancer
Annals of Laboratory Medicine, 2017 Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker of lung cancer; however, few relevant large-scale studies have been published. In this study, we evaluated the utility of serum HE4 for lung cancer detection. HE4 levels were measured in serum samples from 100 lung cancer patients, 57 patients with benign lung diseases, and ...
Choi, Soo In +5 more
openaire +2 more sources
Clinical significance of serum human epididymis protein 4 in liver fibrosis: An experimental study. [PDF]
Medicine (Baltimore), 2020 Abstract Background: Human epididymis protein 4 (HE4) has been identified as marker for renal fibrosis. Present study aimed to investigate the clinical significance of serum HE4 in liver fibrosis. Methods: Serum from 65 liver fibrosis patients, 68 hepatic patients without ...
Hou Y +5 more
europepmc +3 more sources
Testicular degeneration and infertility following arbovirus infection [PDF]
, 2018 Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria +11 more
core +1 more source
Participation of epididymal cysteine-rich secretory proteins in sperm egg fusion and their potential use for male fertility regulation [PDF]
, 2007 Rat protein DE is an androgen-dependent cysteine-rich secretory protein (CRISP) synthesized by proximal epididymal regions. DE, also known as CRISP-1, is localized on the equatorial segment of acrosome-reacted spermatozoa and participates in gamete ...
Busso. Dolores +6 more
core +1 more source
Role of Human Epididymis Protein 4 in Tumour Angiogenesis
, 2023 HE4 is a secretory protein. It is expressed in reproductive tract and respiratory epithelium in normal individuals. Serum level of HE4 is raised in various solid cancers that give us an advantage to use it as a diagnostic and prognostic biomarker. It is an established biomarker of epithelial ovarian cancer [EOC].
Harshita Dubey +13 more
openaire +2 more sources
Open Medicine, 2016 To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
doaj +1 more source
Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]
, 2018 Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev +6 more
core +1 more source
Therapeutic Advances in Respiratory Disease, 2023 Background: Lung cancer is the most common cause of malignant pleural effusion (MPE). Serum human epididymis secretory protein 4 (HE4) is a useful diagnostic marker for lung cancer.
Qian Yang +11 more
semanticscholar +1 more source
Evaluation of tumor marker HE4 assay on the Elecsys 2010 analyzer
Journal of Health Sciences, 2014 Introduction: Whey-acidic protein human epididymis protein 4 (HE4) is a new promising biomarker for epithelial ovarian cancer. The measured HE4 values may depend on the testing procedure used.
Jozo Ćorić +3 more
doaj +1 more source
Evaluation of HE4 as a prognostic biomarker in uterine cervical cancer,
Cancer Treatment and Research Communications, 2023 Introduction: Uterine cervical cancer (UCC) is the fourth most common health problem worldwide among women. Currently available biomarkers CA125, CA199, and CEA for diagnosis or prognostic evaluation of UCC have not got widespread acceptance.
Harshita Dubey +11 more
doaj +1 more source