目的 分析高黏液性肺炎克雷伯菌(hvKP)的临床特征及毒力基因携带情况,方法 对临床分离的肺炎克雷伯菌(KP),通过黏液拉丝试验筛选出hvKP,采用PCR方法检测hvKP的毒力基因和荚膜血清型,采用脉冲场凝胶电泳(PFGE)和多位点序列分型(MLST)方法对hvKP进行分子分型。结果 在631株KP中,共分离hvKP 56株,分离率为8.9%,主要来自于急诊病房、肝胆外科病房;穿刺液、血液和脓液为hvKP的主要标本来源;hvKP的荚膜血清型以K1和K2为主,二者占60.7 ...
王英英, 武彬蔚, 李莉
doaj
Clinical and microbiological characteristics of bloodstream infection caused by Klebsiella pneumoniae harboring rmpA in Japanese adults [PDF]
Nagasaki University (長崎大学)博士(医学)We investigated the clinical features of bloodstream infections (BSIs) caused by Klebsiella pneumoniae harboring rmpA and molecular characteristics of the bacteria.
菊地, 勝太
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ABSTRACT Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) strains present a significant global public health threat due to their high mortality rates. This study investigated the genomic characteristics of seven ST11-K1 CR-hvKP isolates harboring highly ...
Yu-Ling Han +9 more
openaire +3 more sources
Resistance and virulence features of hypermucoviscous Klebsiella pneumoniae from bloodstream infections: Results of a nationwide Italian surveillance study [PDF]
Antonelli, Alberto +4 more
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Outcomes and factors associated with mortality for Enterococcus faecalis and Enterococcus faecium bloodstre am infections: a prospective multi-centre cohort study from the PROBAC project [PDF]
Background Enterococcal BSI represents significant morbidity and mortality, with fatality rates of approximately 20-30%. Infections by E. faecalis and E. faecium have microbiological and clinically differences. Moreover, several studies have demonstrated
Boix Palop, L. +17 more
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Potential in-host evolution of Klebsiella pneumoniae ST147: convergence and the role of capsular alterations in morphotype diversity [PDF]
Klebsiella pneumoniae, an important opportunistic pathogen, is traditionally classified into classic and hypervirulent pathotypes. Convergent strains combining antimicrobial resistance (AMR) and hypervirulence have emerged globally, posing a significant ...
Baecker, Daniel +9 more
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Detection of virulence factors and antimicrobial susceptibility pattern of clinically significant Klebsiella pneumoniae isolates in a tertiary care hospital [PDF]
Introduction: Klebsiella pneumoniae is associated with a variety of infections across all age groups, both in community and hospital settings. Many strains of K.
John, Reena +3 more
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Chao Liu,1 Jiaojiao Shi,2 Jun Guo3,4 1Department of Respiratory Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Beijing, China; 2Department of Respiratory Medicine, Peking University Third ...
Liu C, Shi J, Guo J
doaj
Rapid detection of K1 hypervirulent Klebsiella pneumoniae by MALDI-TOF MS
Hypervirulent strains of Klebsiella pneumoniae (hvKP) are genetic variants of Klebsiella pneumoniae which can cause life-threatening community-acquired infection in healthy individuals.
Yonglu eHuang +6 more
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Identification and response to a putatively hypervirulent, carbapenem-resistant Klebsiella pneumoniae ST395 hospital outbreak in the UK. [PDF]
Here, we describe a putatively hypervirulent, carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) outbreak. Nanopore sequencing guided the infection prevention and control (IPC) responses during the outbreak.
Garvey, Mark I +6 more
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