Results 91 to 100 of about 2,580 (182)

Hypervirulent Klebsiella pneumoniae as a Hospital-Acquired Pathogen in the Intensive Care Unit in Mansoura, Egypt

, 2018
Introduction: Hypervirulent Klebsiella pneumoniae (hvKP) are variants of K. pneumoniae that come up worldwide. hvKP is known in community-acquired infections but little is known about its role in hospital-acquired (HA) infections.
Hassan Salama, Rasha El-Mahdy, Ghada El-Kannishy   +2 more
core   +1 more source

高黏液性肺炎克雷伯菌的临床特征及分子分型

Zhongguo shiyan zhenduanxue, 2022
目的 分析高黏液性肺炎克雷伯菌（hvKP）的临床特征及毒力基因携带情况，方法 对临床分离的肺炎克雷伯菌（KP），通过黏液拉丝试验筛选出hvKP，采用PCR方法检测hvKP的毒力基因和荚膜血清型，采用脉冲场凝胶电泳（PFGE）和多位点序列分型（MLST）方法对hvKP进行分子分型。结果 在631株KP中，共分离hvKP 56株，分离率为8.9%，主要来自于急诊病房、肝胆外科病房；穿刺液、血液和脓液为hvKP的主要标本来源；hvKP的荚膜血清型以K1和K2为主，二者占60.7 ...
王英英, 武彬蔚, 李莉
doaj  

Genomic epidemiology of putative hypervirulent Klebsiella pneumoniae species complex in Dutch patients, January–December 2022

Microbiology Spectrum
Hypervirulent Klebsiella pneumoniae species complex (hvKp) can cause invasive infections with spontaneous abscesses, also in previously healthy individuals.
Karuna E. W. Vendrik, Gijs Teunis, Fardau Anema, Fabian Landman, Angela de Haan, Jeroen Bos, Sandra Witteveen, Annelot F. Schoffelen, Sabine C. de Greeff, Ed J. Kuijper, Antoni P. A. Hendrickx, Daan W. Notermans   +11 more
doaj   +1 more source

Phenotypic and genomic characterization of ST11-K1 CR-hvKP with highly homologous bla _KPC-2 -bearing plasmids in China

mSystems
ABSTRACT Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) strains present a significant global public health threat due to their high mortality rates. This study investigated the genomic characteristics of seven ST11-K1 CR-hvKP isolates harboring highly ...
Yu-Ling Han, Hua Wang, Hong-Zhe Zhu, Ying-Ying Lv, Wen Zhao, Yan-Yan Wang, Jian-Xun Wen, Zhi-De Hu, Jun-Rui Wang, Wen-Qi Zheng   +9 more
openaire   +3 more sources

Virulence factors, capsular serotypes and antimicrobial resistance of hypervirulent klebsiella pneumoniae and classical klebsiella pneumoniae in Southeast Iran

, 2021
Background: The present study was conducted to investigate the distribution of virulence factors, capsular serotypes and antibiotic resistance properties of classical Klebsiella pneumoniae (cKP) and hypermucoviscous/hypervirulent Klebsiella pneumoniae ...
Dehdasht, A.G., Rastegar, S., Hosseini-Nave, H., Moradi, M., Kalantar-Neyestanaki, D.   +4 more
core  

Resistance of hypervirulent Klebsiella pneumoniae to both intracellular and extracellular killing of neutrophils. [PDF]

, 2017
Hypervirulent Klebsiella pneumoniae (HvKP) is hypermucoviscous organism, carrying genes of rmpA and aerobactin, causing serious community-acquired infection and metastatically spread in young healthy hosts.
Hua Wu, Lifeng Wang, Yanning Ma, Dingxia Shen   +3 more
core   +1 more source

High prevalence of hypervirulent Klebsiella pneumoniae infection in the genetic background of elderly patients in two teaching hospitals in China

Infection and Drug Resistance, 2018
Chao Liu,1 Jiaojiao Shi,2 Jun Guo3,4 1Department of Respiratory Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Beijing, China; 2Department of Respiratory Medicine, Peking University Third ...
Liu C, Shi J, Guo J
doaj  

High Prevalence of Hypervirulent Klebsiella pneumoniae Infection in China: Geographic Distribution, Clinical Characteristics, and Antimicrobial Resistance

, 2016
Hypervirulent Klebsiella pneumoniae (hvKP) is traditionally defined by hypermucoviscosity, but data based on genetic background are limited. Antimicrobial-resistant hvKP has been increasingly reported but has not yet been systematically studied.
Zhang, Yawei, Li, Henan, Zhao, Chunjiang, Wang, Ruobing, Chen, Hongbin, Wang, Hui, Li, Shuguang, Wang, Qi, Zhang, Feifei, Wang, Xiaojuan   +9 more
core   +1 more source

Acquisition of a stable and transferable plasmid coharbouring hypervirulence and MDR genes with low fitness cost: Accelerating the dissemination of ST11-KL64 CR-HvKP

Journal of Global Antimicrobial Resistance
This study aimed to delineate the ability of a plasmid, pS130-4, which harboured both hypervirulence and multidrug resistance genes, to disseminate within Klebsiella pneumoniae, as well as its potential formation mechanism.We employed whole-genome sequencing to decipher the genetic architecture of pS130-4.
Binghui Huo, DanDan Wei, QiSen Huang, Shanshan Huang, LinPing Fan, Ping Li, Jiehui Qiu, Qun Ren, ChunPing Wei, Yang Liu   +9 more
openaire   +3 more sources

Diversity of virulence level phenotype of hypervirulent Klebsiella pneumoniae from different sequence type lineage

, 2018
Background Hypervirulent Klebsiella pneumoniae (hvKP) is emerging around the Asian-Pacific region and it is the major cause of the community-acquired pyogenic liver abscesses.
Yunsong Yu, Peng Lan, Danyan Huang, Xiaoting Hua, Yan Jiang, Qiucheng Shi, Jiancang Zhou   +6 more
core   +1 more source