Results 71 to 80 of about 2,369 (178)

Genomic Evolution of the Increasing Prevalent Carbapenem‐Resistant Hypervirulent ST15 Klebsiella pneumoniae

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Purpose ST15 Klebsiella pneumoniae (Kp) is increasingly prevalent in China and worldwide. Currently, the mechanisms underlying the acquisition of hypervirulence‐associated genes in sequence Type 15 (ST15) Kp are still not well studied. The global prevalence of ST15 Kp is increasing, alongside notable increases in both resistance and virulence.
Shuaihua Fan   +6 more
wiley   +1 more source

Unraveling Hypervirulent Klebsiella pneumoniae (hvkp): leveraging the Maga gene as a biomarker for strong biofilm forming hvkp

open access: yes
Abstract Background This study aims to distinguish hypervirulent Klebsiella pneumoniae (hvKp) from its classical counterpart (cKp) by utilizing Potassium tellurite agar (PTA) and the String test, with a focus on biofilm formation. The magA gene is investigated as a potential biomarker for identifying robust biofilm-producing hvKp strains ...
Latha R   +5 more
openaire   +1 more source

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important emerging pathogen leading to serious clinical outcomes as the multidrug‐resistant (MDR) isolates arise. While K. pneumoniae is a well‐known pathogen in human clinical settings, its risks in nonhuman hosts and potential for cross‐species transmission remain poorly understood. In this study, we performed whole‐genome
Qiu Xu   +9 more
wiley   +1 more source

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen   +16 more
wiley   +1 more source

Epidemiological and Genomic Characteristics of blaCTX-M and blaNDM‐Producing K. pneumoniae From Dairy Cows in Henan Province, China

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Extended‐spectrum β‐lactamase (ESBL) and carbapenemase‐producing Klebsiella spp., particularly K. pneumoniae, are emerging threats in both clinical and community settings. To investigate the epidemiology, phylogenetics, and antimicrobial resistance of bovine‐origin strains, 174 bacterial isolates were obtained from 180 mastitic milk samples across ...
Yiming Feng   +9 more
wiley   +1 more source

Clinical and Microbiological Characteristics of Invasive and Hypervirulent Klebsiella pneumoniae Infections in a Teaching Hospital in China

open access: yesInfection and Drug Resistance, 2020
Lijuan Li, Ziyang Yuan, Danna Chen, Xiaoyan Xie, Bashan Zhang Department of Clinical Laboratory, Affiliated Dongguan People’s Hospital, Southern Medical University, Dongguan, Guangdong 523059, People’s Republic of ChinaCorrespondence: Bashan ...
Li L, Yuan Z, Chen D, Xie X, Zhang B
doaj  

Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns

open access: yes, 2022
K1/K2 hvKP strains acquire carbapenem-resistance plasmids, known as CR-hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence plasmids, recognized as hv-CRKP.
Jinzuan Wu (13108660)   +8 more
core   +1 more source

Antibacterial and Osteogenic Applications of Ti‐Cu Alloys: A Review of Current Research and Future Directions

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 23, December 8, 2025.
Given the growing interest in antibiotic‐free implant strategies and the need for biocompatible solutions to combat peri‐implantitis and implant failure, this review gives a timely and comprehensive overview of Ti‐Cu alloys as next‐generation biomaterials.
Brandon Fields   +8 more
wiley   +1 more source

Hypervirulent Klebsiella pneumoniae as a Hospital-Acquired Pathogen in the Intensive Care Unit in Mansoura, Egypt

open access: yes, 2018
Introduction: Hypervirulent Klebsiella pneumoniae (hvKP) are variants of K. pneumoniae that come up worldwide. hvKP is known in community-acquired infections but little is known about its role in hospital-acquired (HA) infections.
Hassan Salama   +2 more
core   +1 more source

Antibacterial and Antibiotic‐Enhancing Activity of 3‐Hydroxy‐4‐methoxycinnamic Acid: Experimental Data and In Silico Predictions

open access: yesChemistrySelect, Volume 10, Issue 47, December 15, 2025.
ABSTRACT The growing bacterial resistance, driven by the inappropriate use of antibiotics, poses a global health threat and demands new therapeutic strategies. Natural phenolic compounds, such as 3‐hydroxy‐4‐methoxycinnamic acid (3H4MCA), stand out due to their antimicrobial and antioxidant properties, showing potential in combating resistant pathogens.
José Thyálisson da Costa Silva   +16 more
wiley   +1 more source

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