Results 71 to 80 of about 2,661 (201)

Gut Commensal Klebsiella pneumoniae Extracellular Vesicles Shape a Liver Microenvironment Conducive to Gut‐Liver Bacterial Translocation and Pro‐Tumorigenic Processes

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Bacterial extracellular vesicles (EVs) are emerging mediators of host–microbe communication; however, their role in human disease remains unclear. Here, we identify two bacterial small tRNAs (tsRNAs) enriched in gut commensal Klebsiella pneumoniae‐derived EVs (KpEVs) that are markedly elevated in the serum of patients with hepatocellular ...
Shogo Tsubaki, Sho Nashimoto, Rika Tanaka, Touya Toyomoto, Hiroyasu Tsutsuki, Ken Kato, Jun Nakayama, Kiminori Kimura, Kazuki Oshima, Yusuke Yamamoto, Takuji Okusaka, Minoru Esaki, Nobuhiro Kawai, Nobuyuki Ota, Yusuke Yoshioka, Takahiro Ochiya, Yoshimasa Saito, Tomohiro Sawa, Katsuto Hozumi, Juntaro Matsuzaki, Hitoshi Tsugawa   +20 more
wiley   +1 more source

Uncomplicated pharyngitis due to family transmission of hypervirulent Klebsiella pneumoniae [PDF]

We describe two cases of uncomplicated pharyngitis caused by hypervirulent Klebsiella pneumoniae (hvKp) in a family, initially in an immunocompetent adolescent, followed by possible household spread resulting in similar presentations in the patient's ...
Chalmers, Alisa C, Gonzalez-Ferrer, Shekina, Gray, Hannah K, Malhotra, Sanchi, Whitehill, Gregory D, Yang, Shangxin   +5 more
core   +1 more source

antimicrobial resistance profile and molecular characterization [PDF]

, 2021
Funding Information: CISM is supported by the Government of Mozambique and the Spanish Agency for International Development Cooperation (AECID). CHAMPS is funded by the Bill & Melinda Gates Foundation under the Grant OPP1126780 to Robert Breiman ...
Bassat, Quique, Blau, Dianna M., Boisen, Nadia, Breiman, Robert F., Cossa, Anélsio, Garrine, Marcelino, Hurtado, Juan Carlos, Mandomando, Inácio, Massinga, Arsénia J., Massora, Sergio, Messa, Augusto, Mucavele, Hélio, Nhampossa, Tacilta, Nobela, Nélio A., Ordi, Jaume, Sitoe, António, Varo, Rosauro, Whitney, Cynthia G.   +17 more
core   +1 more source

Mechanism of virulence polymorphism in CR-hvKP strains from the same source

Microbiology Spectrum
ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKP) has become a major public health issue worldwide due to its high case fatality rate and transmissible nature. The plasmid containing drug-resistant and virulence genes obtained by CRKP can evolve into carbapenem ...
Jianhua Fang, Hongyi Lai, Miao Deng, Yanfang Mei, Dehua Chen, Tieying Hou, Tianxin Xiang   +6 more
openaire   +3 more sources

Lemierre's Syndrome Caused by Klebsiella pneumoniae: Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
Axial contrast‐enhanced chest CT demonstrating multiple peripheral cavitary nodules and consolidations, predominantly in the right lower lobe, consistent with septic pulmonary emboli (arrows). ABSTRACT Klebsiella pneumoniae is an uncommon but increasingly recognized cause of Lemierre's syndrome, a condition classically associated with Fusobacterium ...
Abril Aguilar Guerrero, Eduardo Porras Rosales   +1 more
wiley   +1 more source

Hypervirulent Klebsiella pneumoniae: Epidemiology, virulence factors, and antibiotic resistance [PDF]

, 2023
Human infections induced by Klebsiella pneumoniae (K. pneumoniae) include pneumonia; urinary tract infections, liver abscesses, bacteremia, and others. The introduction and spread of the hypervirulent K.
Abdelrhman Abdelmoktader, Enas M. Hefzy, Mahmoud A.F. Khalil, Reda M. Taha, Safaa Abd El Salam   +4 more
core   +1 more source

Co‐Occurrence of Resistance to Aminoglycosides and Carbapenems in Klebsiella pneumoniae: A Critical Threat to Public Health

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Antimicrobial resistance (AMR) in Klebsiella pneumoniae, especially the co‐occurrence of resistance to aminoglycosides and carbapenems, represents a serious threat to global public health. This study reviews the prevalence of this combined resistance, analyzes the underlying mechanisms, and evaluates its impact on clinical practice and public health ...
Rafael Artur de Queiroz Cavalcanti de Sa, Tainara Fernandes Dantas, Sérgio Costa Júnior, Karolayne Oliveira da Silva, Maria Cecília Ferreira Galindo, Amanda Vieira de Barros, John Eversong Lucena de Vasconcelos, Radosław Kowalski, Grażyna Kowalska, Rafal Rowinski, Henrique Douglas Melo Coutinho, Maria Betânia Melo Oliveira, Divakar Sharma   +12 more
wiley   +1 more source

Detection of extensively drug-resistant and hypervirulent Klebsiella pneumoniae ST15, ST147, ST377 and ST442 in Iran [PDF]

, 2022
In this study, we focused on the emergence of extensively drug-resistant (XDR), pandrug-resistant (PDR), and hypervirulent Klebsiella pneumoniae (hvKP) in Iran. During 2018 to 2020 a total of 52 K.
Ardebili, Abdollah, Davoudabadi, Sara, Faghihloo, Ebrahim, Goudarzi, Hossein, Goudarzi, Mehdi, Hashemi, Ali, Sharahi, Javad Yasbolaghi   +6 more
core   +1 more source

Genomic Evolution of the Increasing Prevalent Carbapenem‐Resistant Hypervirulent ST15 Klebsiella pneumoniae

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Purpose ST15 Klebsiella pneumoniae (Kp) is increasingly prevalent in China and worldwide. Currently, the mechanisms underlying the acquisition of hypervirulence‐associated genes in sequence Type 15 (ST15) Kp are still not well studied. The global prevalence of ST15 Kp is increasing, alongside notable increases in both resistance and virulence.
Shuaihua Fan, Pengcheng Du, Yunfei Tang, Huaiqing Qi, Chao Liu, Jun Guo, Mohamed Salah Abbassi   +6 more
wiley   +1 more source

Severe co-infection caused by difficult-to-diagnose hypermucoviscous Klebsiella pneumoniae K1-ST82 in a patient with COVID-19: a case report [PDF]

BMC Infectious Diseases volume 24, Article number: 1215 ...
Hanada, Hiroyuki, Hayashi, Wataru, Itoga, Masamichi, Kayama, Shizuo, Kimura, Masahiko, Sugai, Motoyuki, Sugawara, Yo, Tasaka, Sadatomo, Yu, Liansheng   +8 more
core   +1 more source