Results 51 to 60 of about 2,667 (163)

Phagocytosis of neutrophils against HvKP-K1, HvKP-K2 and cKP.

, 2017
The rate of phagocytosis against cKP (15 isolates) was higher than that against HvKP-K1 (16 isolates) or HvKP-K2 (14 isolates) at 10, 30, 60 min.
Yanning Ma (3143427), Hua Wu (2707), Dingxia Shen (425821), Lifeng Wang (121568)   +3 more
core   +1 more source

Survival of cKP, HvKP-K1 and HvKP-K2 within human neutrophils.

, 2017
The survival index was calculated with the equation described in the method. The survival index of cKP (15 isolates) was lower than that of HvKP-K1 (16 isolates) or HvKP-K2 (14 isolates). Each strain was repeated twice and averaged.
Yanning Ma (3143427), Hua Wu (2707), Dingxia Shen (425821), Lifeng Wang (121568)   +3 more
core   +1 more source

In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates

Frontiers in Microbiology, 2020
ObjectiveThe emergence of carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) strains poses a significant public threat, and effective antimicrobial therapy is urgently needed.
Mingju Hao, Xiaohong Shi, Jingnan Lv, Siqiang Niu, Shiqing Cheng, Hong Du, Fangyou Yu, Yi-Wei Tang, Barry N. Kreiswirth, Haifang Zhang, Liang Chen   +10 more
doaj   +1 more source

Resistance of hypervirulent Klebsiella pneumoniae to cathepsin B-mediated pyroptosis in murine macrophages

Frontiers in Immunology, 2023
IntroductionHypervirulent Klebsiella pneumoniae (hvKp) has emerged as a clinically significant global pathogen in the last decade. However, the host immune responses of the macrophages during hvKp infection are largely unknown.
Jin Kyung Kim, Hui-Jung Jung, Miri Hyun, Ji Yeon Lee, Jong-Hwan Park, Seong-Il Suh, Won-Ki Baek, Hyun ah Kim   +7 more
doaj   +1 more source

Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns

, 2022
K1/K2 hvKP strains acquire carbapenem-resistance plasmids, known as CR-hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence plasmids, recognized as hv-CRKP.
Jinzuan Wu (13108660), Dakang Hu (647924), Xiao Liu (65413), Ying Zhou (25031), Weiwen Wang (740765), Xiaofei Jiang (2142271), Dongxing Tian (8870936), Wenjie Chen (130753), Qing Mu (2248399)   +8 more
core   +1 more source

Disseminated Klebsiella pneumoniae Infection Mimicking Multiple Colonic Subepithelial Lesions: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT We report a rare case of disseminated Klebsiella pneumoniae infection mimicking multiple subepithelial lesion (SEL)‐like elevations throughout the colon. A 73‐year‐old man was referred for the treatment of diarrhea, edema, and anemia. Colonoscopy revealed numerous SEL‐like elevations from the cecum to the rectum, raising suspicion for ...
Yoshiaki Kobayashi, Tadanobu Nagaya, Mai Iwaya, Hiroshi Ikeuchi, Takuma Okamura, Takeshi Uehara, Yugo Iwaya   +6 more
wiley   +1 more source

Rhabdomyolysis secondary to hypervirulent Klebsiella pneumoniae infection: A case report

, 2022
Hypervirulent Klebsiella pneumoniae (hvKP) is recognized as a lifethreatening community‐acquired infection associated with pyogenic liver abscess. However, rhabdomyolysis secondary to hvKP infection is rare.
Taiju Miyagami, Toshio Naito, Keiko Taga, Naoko Niimi, Chieko Mitaka   +4 more
core   +1 more source

The Galleria mellonella Infection Model Does Not Accurately Differentiate between Hypervirulent and Classical Klebsiella pneumoniae

mSphere, 2020
Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging pathogen of increasing concern due to its ability to cause serious organ and life-threatening infections in healthy individuals and its increasing acquisition of antimicrobial resistance ...
Thomas A. Russo, Ulrike MacDonald
doaj   +1 more source

Longitudinal Molecular Epidemiology and Genomic Surveillance of Carbapenem‐Resistant Klebsiella pneumoniae in the Gut of Healthy Individuals in China

MedComm, Volume 7, Issue 8, August 2026.
Using 16,040 stool samples from healthy individuals across 30 Chinese provinces (2016–2024), we performed longitudinal genomic surveillance of carbapenem‑resistant Klebsiella pneumoniae (CRKP) colonizing the gut. We reveal rising community CRKP prevalence, especially in southern China, a shift from blaKPC‐2 to plasmid‑borne blaNDM‐5 on IncHI2/IncHI2A ...
Zelin Yan, Yan Li, Yi Sun, Qiaoling Sun, Congcong Liu, Yanyan Zhang, Yuchen Wu, Hongwei Zhou, Shangshang Qin, Gongxiang Chen, Ruichao Li, Rong Zhang   +11 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source