Results 31 to 40 of about 2,369 (178)

Comparative Proteomic Profiling of Clinical <i>Klebsiella pneumoniae</i> Strains and the Corresponding Outer Membrane Vesicles. [PDF]

J Extracell Biol
ABSTRACT Klebsiella pneumoniae (K. pneumoniae) has become a global threat due to the convergence of carbapenem resistance and hypervirulence. Outer membrane vesicles (OMVs) play important roles in bacterial pathogenicity, yet their functional coordination with strains remains unclear.
Li Z, Xi J, Jia X, He Y, Wang G, Chen S, Chu X, Zhang Q, Zhu Y, Yu W, Jia P, Liu X, Yang Q.   +12 more
europepmc   +2 more sources

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil. [PDF]

Microbiol Immunol
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Camargo CH, Costa ABN, Yamada AY, Miranda DS, Ferraro PSP, Souza AR, Bertani AMJ, Campos KR, Santos MBN, Rissetti RM, Paula CL, Paz PJL, Soares MSD, Salvador C, Pieri GP, Higa JS, Souza DDS, Ribeiro MG, Sacchi CT, Tiba-Casas MR, Madalosso G, Assis DB.   +21 more
europepmc   +2 more sources

Clinical challenges with hypervirulent Klebsiella pneumoniae (hvKP) in China

Journal of Translational Internal Medicine, 2021
Abstract Hypervirulent Klebsiella pneumoniae (hvKp) is an evolving pathotype with higher virulence than classical K. pneumoniae (cKp) and is characterized by community-acquired, multiple sites of infections and young and healthy hosts. hvKP infections were primarily found in East Asia and have been increasingly reported worldwide over ...
Chen, Yanzhu, Chen, Yi
openaire   +2 more sources

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon. [PDF]

Microbiologyopen
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Zaylaa M, Farha R, Taleb J, Saad A, Gharbawy OE, Sarraf R, Kassam I, Hamdach C, Bissar N.   +8 more
europepmc   +2 more sources

Molecular detection of hypervirulent Klebsiella pneumoniae (hvKp) in Egyptian poultry. [PDF]

BMC Vet Res
Supplementary Material 1.
Ahmed ZS, Abdel-Kader F, Hamza D, Ashour R.   +3 more
europepmc   +3 more sources

A typical multisite invasive infection caused by hvKP: A case report and literature review

Medicine, 2022
Rationale: Hypervirulent K. pneumoniae (hvKP) is a new variant of K. pneumoniae that can caused metastatic spreading by blood, including Splenic abscess, endogenous endophthalmitis, purulent meningitis. This report described a case of A typical multisite invasive infection caused by hvKP and carry out a historical review of the
Liu, Jia, Dai, Mingying, Sun, Qiang, Fang, Wei   +3 more
openaire   +2 more sources

In vitro activity of ceftazidime-avibactam, imipenem-relebactam, aztreonam-avibactam, and comparators toward carbapenem-resistant and hypervirulent Klebsiella pneumoniae isolates

Microbiology Spectrum, 2023
Carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKP) strains are increasingly reported, posing a significant threat to public health. Therefore, effective antimicrobial therapy is urgently needed.
Dan Li, Hua Yu, Xiangning Huang, Shanshan Long, Jie Zhang   +4 more
doaj   +1 more source

Detection of extensively drug-resistant and hypervirulent Klebsiella pneumoniae ST15, ST147, ST377 and ST442 in Iran [PDF]

, 2021
In this study, we focused on the emergence of extensively drug-resistant (XDR), pandrug-resistant (PDR), and hypervirulent Klebsiella pneumoniae (hvKP) in Iran. During 2018 to 2020 a total of 52 K.
Ali Hashemi, Faghihloo, Ebrahim, Javad Yasbolaghi Sharahi, Faghihloo, E., Goudarzi, H., Ebrahim Faghihloo, Hossein Goudarzi, Mehdi Goudarzi, Goudarzi, M., Sara Davoudabadi, Abdollah Ardebili, Goudarzi, Mehdi, Ardebili, Abdollah, Sharahi, Javad Yasbolaghi, Hashemi, Ali, Goudarzi, Hossein, Sharahi, J.Y., Hashemi, A., Ardebili, A., Davoudabadi, S., Davoudabadi, Sara   +20 more
core   +1 more source

The threat of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) [PDF]

Biomedical Research, 2018
Klebsiella pneumoniae is one of clinically important opportunistic pathogens responsible for community-acquired and nosocomial infections in immunocompromised individuals. The increasing prevalence of carbapenem-resistant K. pneumoniae (CRKP) poses a serious threat to public health worldwide. With antibiotic resistance, hypervirulent K.
Chang Ro Lee, Kwang Seung Park, Jung Hun Lee, Jeong Ho Jeon, Young Bae Kim, Byeong Chul Jeong, Sang Hee Lee   +6 more
openaire   +1 more source

Molecular and clinical characterization of hypervirulent Klebsiella pneumoniae isolates from individuals with urinary tract infections

Frontiers in Cellular and Infection Microbiology, 2022
Despite being a significant public health concern, hypervirulent Klebsiella pneumoniae (hvKP) has rarely been investigated in urinary tract infections (UTIs).
Jun Li, Jun Li, Mengli Tang, Zhaojun Liu, Fengjun Xia, Changhang Min, Yongmei Hu, Yongmei Hu, Haichen Wang, Haichen Wang, Mingxiang Zou, Mingxiang Zou   +11 more
doaj   +1 more source