Results 31 to 40 of about 2,667 (163)

Incidence, risk factors and clinical outcomes of patients with hypermucoviscoid Klebsiella in a tertiary intensive care unit

Journal of Global Infectious Diseases, 2020
Background and Objectives: Hypermucoviscoid Klebsiella(hvKP), a dreaded variant of Klebsiella, so far, fewer cases were reported from the community. This study was designed to evaluate the incidence of hvKP isolates, risk factors for hvKP infections ...
Vimal Bhardwaj, Vellaichamy Muthupandi Annapandian, Annie Rofeena Sinazer, Arjun Alva, Shiva Prasad   +4 more
doaj   +1 more source

Detection of extensively drug-resistant and hypervirulent Klebsiella pneumoniae ST15, ST147, ST377 and ST442 in Iran [PDF]

, 2021
In this study, we focused on the emergence of extensively drug-resistant (XDR), pandrug-resistant (PDR), and hypervirulent Klebsiella pneumoniae (hvKP) in Iran. During 2018 to 2020 a total of 52 K.
Ali Hashemi, Faghihloo, Ebrahim, Javad Yasbolaghi Sharahi, Faghihloo, E., Goudarzi, H., Ebrahim Faghihloo, Hossein Goudarzi, Mehdi Goudarzi, Goudarzi, M., Sara Davoudabadi, Abdollah Ardebili, Goudarzi, Mehdi, Ardebili, Abdollah, Sharahi, Javad Yasbolaghi, Hashemi, Ali, Goudarzi, Hossein, Sharahi, J.Y., Hashemi, A., Ardebili, A., Davoudabadi, S., Davoudabadi, Sara   +20 more
core   +1 more source

Outer membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae

Emerging Microbes and Infections, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is a notorious clinical pathogen that is more likely to cause severe primary and metastatic abscesses. The dissemination of antimicrobial-resistant hvKp isolates has been reported worldwide, posing a great ...
Yuneng Hua, Jingyu Wang, Mei Huang, Yiyi Huang, Ruyi Zhang, Fan Bu, Biao Yang, Juanjiang Chen, Xiaomin Lin, Xiumei Hu, Lei Zheng, Qian Wang   +11 more
doaj   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent <i>Klebsiella pneumoniae</i>. [PDF]

Imeta
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Lim C, Zheng J, Cheam G, Yong M, Chen H, Ting A, Chen Y, Wang Q, Nagarajan N, Gan YH.   +9 more
europepmc   +2 more sources

Screening of Klebsiella pneumoniae Isolates for Carbapenemase and Hypervirulence-Associated Genes by Combining the Eazyplex^® Superbug CRE and hvKp Assays [PDF]

, 2023
The acquisition of hypervirulence-associated genes by carbapenemase-producing Klebsiella pneumoniae is being increasingly observed, and easy-to-use diagnostic tests are needed for the surveillance of the hypervirulent K. pneumoniae (hvKp).
Martin A. Fischer, Sylvia Stoll, Bettina Löffler, Edel, Birgit, Yvonne Pfeifer, Wolfgang Pfister, Fischer, Martin A., Birgit Edel, Löffler, Bettina, Rödel, Jürgen, Pfister, Wolfgang, Jürgen Rödel, Pfeifer, Yvonne, Stoll, Sylvia   +13 more
core   +1 more source

In vitro activity of ceftazidime-avibactam, imipenem-relebactam, aztreonam-avibactam, and comparators toward carbapenem-resistant and hypervirulent Klebsiella pneumoniae isolates

Microbiology Spectrum, 2023
Carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKP) strains are increasingly reported, posing a significant threat to public health. Therefore, effective antimicrobial therapy is urgently needed.
Dan Li, Hua Yu, Xiangning Huang, Shanshan Long, Jie Zhang   +4 more
doaj   +1 more source

A case of Klebsiella pneumoniae hypervirulent phenotype causing necrotizing fasciitis of chest wall: A mono-microbial entity emerging in the Indian subcontinent

Journal of Family Medicine and Primary Care, 2022
Necrotizing fasciitis of the chest wall or upper torso is a rare clinical entity. Monomicrobial Klebsiella pneumoniae as a causative agent of necrotizing fasciitis is far less common than the polymicrobial etiology.
Rituparna Dasgupta, Arghya Das
doaj   +1 more source

Image_2_Clinical and genomic characterization of hypervirulent Klebsiella pneumoniae (hvKp) infections via passive surveillance in Southern California, 2020–2022.pdf

, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is more invasive and virulent than classical K. pneumoniae, and requires specialized treatment. To raise clinical awareness, this study determined the prevalence, clinical characteristics, and genomic ...
Edwin Kamau (282162), Elizabeth L. Ranson (13957578), Elke S. Bergmann-Leitner (10918220), Omai B. Garner (245658), Shangxin Yang (9394832), Allison T. Tsan (13957581)   +5 more
core   +1 more source

Table_2_Clinical and genomic characterization of hypervirulent Klebsiella pneumoniae (hvKp) infections via passive surveillance in Southern California, 2020–2022.docx

, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is more invasive and virulent than classical K. pneumoniae, and requires specialized treatment. To raise clinical awareness, this study determined the prevalence, clinical characteristics, and genomic ...
Edwin Kamau (282162), Elizabeth L. Ranson (13957578), Elke S. Bergmann-Leitner (10918220), Omai B. Garner (245658), Shangxin Yang (9394832), Allison T. Tsan (13957581)   +5 more
core   +1 more source

Molecular and clinical characterization of hypervirulent Klebsiella pneumoniae isolates from individuals with urinary tract infections

Frontiers in Cellular and Infection Microbiology, 2022
Despite being a significant public health concern, hypervirulent Klebsiella pneumoniae (hvKP) has rarely been investigated in urinary tract infections (UTIs).
Jun Li, Jun Li, Mengli Tang, Zhaojun Liu, Fengjun Xia, Changhang Min, Yongmei Hu, Yongmei Hu, Haichen Wang, Haichen Wang, Mingxiang Zou, Mingxiang Zou   +11 more
doaj   +1 more source