Results 11 to 20 of about 2,369 (178)

Hypervirulent Klebsiella pneumoniae (hvKp): Overview, Epidemiology, and Laboratory Detection

Pathogens and Immunity
Klebsiella pneumoniae (Kp) is a Gram-negative pathogen responsible for both hospital- and community-acquired infections. Kp is classified into 2 distinct pathotypes: classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp).
Dania Al Ismail, Edgar I. Campos-Madueno, Valentina Donà, Andrea Endimiani   +3 more
doaj   +4 more sources

Antimicrobial Resistance Pattern, Pathogenicity and Molecular Properties of Hypervirulent Klebsiella pneumonia (hvKp) among Hospital-Acquired Infections in the Intensive Care Unit (ICU)

Microorganisms, 2023
Hypervirulent Klebsiella pneumoniae (hvKp) is a new emerging variant of K. pneumoniae that is increasingly reported worldwide. The variant hvKp is known to cause severe invasive community-acquired infections such as metastatic meningitis, pyogenic liver ...
Mohanned Talal Alharbi, Mohammed S. Almuhayawi, Mohammed K. Nagshabandi, Muyassar K. Tarabulsi, Mohammed H. Alruhaili, Hattan S. Gattan, Soad K. Al Jaouni, Samy Selim, Awadh Alanazi, Yasir Alruwaili, Shaimaa Mohamed Zaied, Osama Ahmed Faried   +11 more
doaj   +4 more sources

The face of hypervirulent Klebsiella pneumoniae isolated from clinical samples of two Iranian teaching hospitals [PDF]

Annals of Clinical Microbiology and Antimicrobials, 2021
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern. In this study, both phenotypic and genotypic tests were used to detect hvKp.
Rahimeh Sanikhani, Mohammad Moeinirad, Hamid Solgi, Azar Hadadi, Fereshteh Shahcheraghi, Farzad Badmasti   +5 more
doaj   +6 more sources

Early Response of Antimicrobial Resistance and Virulence Genes Expression in Classical, Hypervirulent, and Hybrid hvKp-MDR Klebsiella pneumoniae on Antimicrobial Stress [PDF]

Antibiotics, 2021
Klebsiella pneumoniae is an increasingly important hospital pathogen. Classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp) are two distinct evolutionary genetic lines. The recently ongoing evolution of K. pneumoniae resulted in the generation of hybrid hvKP-MDR strains. K.
Anastasiia D. Fursova, Mikhail V. Fursov, Evgenii I. Astashkin, Tatiana S. Novikova, Galina N. Fedyukina, Angelina A. Kislichkina, Irina A. Alexandrova, Olga N. Ershova, Ivan A. Dyatlov, Nadezhda K. Fursova   +9 more
openaire   +4 more sources

Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor

Annals of Clinical Microbiology and Antimicrobials, 2019
Background The definition of hypervirulent Klebsiella pneumoniae (hvKp), traditionally regarded as hypermucoviscosity, is controversial. However, data based on both phenotype (hypermucoviscous) and genetic (aerobactin) criteria are limited.
Chao Liu, Jun Guo
doaj   +2 more sources

Interaction of multidrug-resistant hypervirulent Klebsiella pneumoniae with components of human innate host defense

mBio, 2023
Klebsiella pneumoniae is an important cause of healthcare-associated infections worldwide. This opportunistic pathogen, known as classical K. pneumoniae (cKp), typically causes infections in individuals with comorbidities.
Frank R. DeLeo, Adeline R. Porter, Scott D. Kobayashi, Brett Freedman, Mingju Hao, Jianping Jiang, Yi-Tsung Lin, Barry N. Kreiswirth, Liang Chen   +8 more
doaj   +2 more sources

Clinical and Molecular Analysis of ST11-K47 Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae: A Strain Causing Liver Abscess

Pathogens, 2022
Klebsiella pneumoniae has been the predominant pathogen of liver abscess, but ST11-K47 carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) has rarely been studied as the causative organism. We identified an ST11-K47 CR-hvKP (HvKp-su1) from
Zhen Cai, Tianye Jia, Mingfang Pu, Shuyong Zhang, Jingxia Zhang, Ronghua Geng, Suming Chen, Yahao Li, Huahao Fan, Yigang Tong, Fen Qu   +10 more
doaj   +2 more sources

Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China

Antimicrobial Resistance and Infection Control, 2018
Background Aerobactin is a critical factor for the hypervirulent Klebsiella pneumoniae (hvKp), but data for the aerobactin-positive genotype of hvKp in elderly persons with ventilator-associated pneumonia (VAP) is limited. The purpose of this study is to
Chao Liu, Jun Guo
doaj   +2 more sources

A strategy for controlling Hypervirulent Klebsiella pneumoniae: inhibition of ClpV expression

BMC Microbiology
The emergence and prevalence of hypervirulent Klebsiella pneumoniae (hvKP) have proposed a great challenge to control this infection. Therefore, exploring some new drugs or strategies for treating hvKP infection is an urgent issue for scientific ...
Wenke Liu, Dan Wang, Qiangxing He, Shiwen Cao, Jiaxin Cao, Huajie Zhao, Junwei Cui, Fan Yang   +7 more
doaj   +2 more sources

Microbiological characteristics of hypermucoviscous Klebsiella pneumoniae isolates from different body fluids

Journal of Infection in Developing Countries, 2017
Introduction: Reports of hypermucoviscous Klebsiella pneumoniae (hvKP) isolated from fluids other than blood or abscess are rare. The aim of the study was to compare clinical and microbiological characteristics of hvKP found in blood or abscess fluid ...
Xiumei Xiao, Bei Yao, Qingtao Zhou, Jie Zhang   +3 more
doaj   +3 more sources