Results 21 to 30 of about 2,661 (201)

The threat of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) [PDF]

Biomedical Research, 2018
Klebsiella pneumoniae is one of clinically important opportunistic pathogens responsible for community-acquired and nosocomial infections in immunocompromised individuals. The increasing prevalence of carbapenem-resistant K. pneumoniae (CRKP) poses a serious threat to public health worldwide. With antibiotic resistance, hypervirulent K.
Chang Ro Lee, Kwang Seung Park, Jung Hun Lee, Jeong Ho Jeon, Young Bae Kim, Byeong Chul Jeong, Sang Hee Lee   +6 more
openaire   +1 more source

A typical multisite invasive infection caused by hvKP: A case report and literature review

Medicine, 2022
Rationale: Hypervirulent K. pneumoniae (hvKP) is a new variant of K. pneumoniae that can caused metastatic spreading by blood, including Splenic abscess, endogenous endophthalmitis, purulent meningitis. This report described a case of A typical multisite invasive infection caused by hvKP and carry out a historical review of the
Liu, Jia, Dai, Mingying, Sun, Qiang, Fang, Wei   +3 more
openaire   +2 more sources

Early Response of Antimicrobial Resistance and Virulence Genes Expression in Classical, Hypervirulent, and Hybrid hvKp-MDR Klebsiella pneumoniae on Antimicrobial Stress [PDF]

Antibiotics, 2021
Klebsiella pneumoniae is an increasingly important hospital pathogen. Classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp) are two distinct evolutionary genetic lines. The recently ongoing evolution of K. pneumoniae resulted in the generation of hybrid hvKP-MDR strains. K.
Anastasiia D. Fursova, Mikhail V. Fursov, Evgenii I. Astashkin, Tatiana S. Novikova, Galina N. Fedyukina, Angelina A. Kislichkina, Irina A. Alexandrova, Olga N. Ershova, Ivan A. Dyatlov, Nadezhda K. Fursova   +9 more
openaire   +3 more sources

Clinical and Molecular Analysis of ST11-K47 Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae: A Strain Causing Liver Abscess

Pathogens, 2022
Klebsiella pneumoniae has been the predominant pathogen of liver abscess, but ST11-K47 carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) has rarely been studied as the causative organism. We identified an ST11-K47 CR-hvKP (HvKp-su1) from
Zhen Cai, Tianye Jia, Mingfang Pu, Shuyong Zhang, Jingxia Zhang, Ronghua Geng, Suming Chen, Yahao Li, Huahao Fan, Yigang Tong, Fen Qu   +10 more
doaj   +1 more source

Bacteriological characteristics of hypervirulent Klebsiella pneumoniae rmpA gene (hvKp-rmpA)-harboring strains in the south of Iran

Iranian Journal of Microbiology, 2022
Background and Objectives: To provide data on the occurrence of classical K. pneumoniae (cKp) and hypervirulent Klebsi- ella pneumoniae (hvKp) strains harboring the gene encoding regulator of mucoid phenotype A (rmpA) and evaluated charac- teristics of virulence biomarkers, carbapenemase, extended-spectrum-β-lactamase (ESBL)-producing, and capsule ...
Saeed Shoja, Maryam Ansari, Saman Bengar, Azam Rafiei, Jebreil Shamseddin, Hesam Alizade   +5 more
openaire   +3 more sources

Molecular and clinical characterization of hypervirulent Klebsiella pneumoniae isolates from individuals with urinary tract infections

Frontiers in Cellular and Infection Microbiology, 2022
Despite being a significant public health concern, hypervirulent Klebsiella pneumoniae (hvKP) has rarely been investigated in urinary tract infections (UTIs).
Jun Li, Jun Li, Mengli Tang, Zhaojun Liu, Fengjun Xia, Changhang Min, Yongmei Hu, Yongmei Hu, Haichen Wang, Haichen Wang, Mingxiang Zou, Mingxiang Zou   +11 more
doaj   +1 more source

Classical and γδ T cells are each independently sufficient to establish protection against a classical strain of Klebsiella pneumoniae [PDF]

, 2022
Infections with classical strains of the Gram-negative ...
Mackel, Joseph J, Morffy Smith, Catherine, Rosen, David A, Twentyman, Joy, Wasbotten, Rachel K   +4 more
core   +3 more sources

Incidence, risk factors and clinical outcomes of patients with hypermucoviscoid Klebsiella in a tertiary intensive care unit

Journal of Global Infectious Diseases, 2020
Background and Objectives: Hypermucoviscoid Klebsiella(hvKP), a dreaded variant of Klebsiella, so far, fewer cases were reported from the community. This study was designed to evaluate the incidence of hvKP isolates, risk factors for hvKP infections ...
Vimal Bhardwaj, Vellaichamy Muthupandi Annapandian, Annie Rofeena Sinazer, Arjun Alva, Shiva Prasad   +4 more
doaj   +1 more source

Interaction of multidrug-resistant hypervirulent Klebsiella pneumoniae with components of human innate host defense

mBio, 2023
Klebsiella pneumoniae is an important cause of healthcare-associated infections worldwide. This opportunistic pathogen, known as classical K. pneumoniae (cKp), typically causes infections in individuals with comorbidities.
Frank R. DeLeo, Adeline R. Porter, Scott D. Kobayashi, Brett Freedman, Mingju Hao, Jianping Jiang, Yi-Tsung Lin, Barry N. Kreiswirth, Liang Chen   +8 more
doaj   +1 more source

Community-acquired invasive liver abscess syndrome caused by a K1 serotype Klebsiella pneumoniae isolate in Brazil: a case report of hypervirulent ST23 [PDF]

, 2014
Universidade Federal de São Paulo (UNIFESP) Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) Departamento de Medicina Divisão de Doenças InfecciosasUNIFESP, Depto. de MedicinaUNIFESP, Depto.
Coutinho, Rosane L, Descio, Fernanda J, Furtado, Guilherme Hc, Gales, Ana Cristina, Nicoletti, Adriana Giannini, Pinto, Flavia Cl, Rodrigues-costa, Fernanda, Silva, Ana Carolina R da, Visconde, Marina F   +8 more
core   +3 more sources