Results 21 to 30 of about 2,580 (182)

A strategy for controlling Hypervirulent Klebsiella pneumoniae: inhibition of ClpV expression

BMC Microbiology
The emergence and prevalence of hypervirulent Klebsiella pneumoniae (hvKP) have proposed a great challenge to control this infection. Therefore, exploring some new drugs or strategies for treating hvKP infection is an urgent issue for scientific ...
Wenke Liu, Dan Wang, Qiangxing He, Shiwen Cao, Jiaxin Cao, Huajie Zhao, Junwei Cui, Fan Yang   +7 more
doaj   +2 more sources

Microbiological characteristics of hypermucoviscous Klebsiella pneumoniae isolates from different body fluids [PDF]

Journal of Infection in Developing Countries, 2017
Introduction: Reports of hypermucoviscous Klebsiella pneumoniae (hvKP) isolated from fluids other than blood or abscess are rare. The aim of the study was to compare clinical and microbiological characteristics of hvKP found in blood or abscess fluid ...
Xiumei Xiao, Bei Yao, Qingtao Zhou, Jie Zhang   +3 more
doaj   +2 more sources

Clinical use of tigecycline may contribute to the widespread dissemination of carbapenem-resistant hypervirulent Klebsiella pneumoniae strains

Emerging Microbes and Infections
The emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) poses grave threats to human health. These strains increased dramatically in clinical settings in China in the past few years but not in other parts of the world.
Miaomiao Xie, Lianwei Ye, Kaichao Chen, Qi Xu, Chen Yang, Xiangnan Chen, Edward Wai-Chi Chan, Fuyong Li, Sheng Chen   +8 more
doaj   +2 more sources

Investigation of the therapeutic efficacy and resistance mechanisms of lytic phages targeting ST218 KL57 CR-hvKP

mSystems
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) infection is gradually increasing globally. Phage therapy is a viable application as an alternative to antibiotics.
Meilin Wu, Xu, Li, Mingjie Qiu, Li, Jiayang, Jiajie Wang, Qiu, Mingjie, Jiayang Li, Shuanghong Yang, Yun Zhao, Sai Tian, Dou, Liuqing, Liuqing Dou, Li Xu, Yang, Shuanghong, Zhitao Zhou, Zhao, Yun, Wang, Jiajie, Wu, Xiuwen, Xiuwen Wu, Wu, Meilin, Ren, Jianan, Wu, Wenqi, Tian, Sai, Zhou, Zhitao, Jianan Ren, Wenqi Wu   +25 more
core   +3 more sources

A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics

Emerging Infectious Diseases
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K.
Thomas A. Russo, Francois Lebreton, Patrick T. McGann   +2 more
doaj   +2 more sources

Genomic insights unveil the plasmid transfer mechanism and epidemiology of hypervirulent Klebsiella pneumoniae in Vietnam [PDF]

Nature Communications
Hypervirulent Klebsiella pneumoniae (hvKp) is a significant cause of severe invasive infections in Vietnam, yet data on its epidemiology, population structure and dynamics are scarce.
Quynh Nguyen, Yen Thi Phuong Nguyen, Tuyen Thanh Ha, Dung Thi Ngoc Tran, Phat Vinh Voong, Vinh Chau, Phuong Luong Nha Nguyen, Ngan Thi Quynh Le, Lan Phu Huong Nguyen, To Thi Nguyen Nguyen, Tan Van Trinh, Juan J. Carrique-Mas, Stephen Baker, Guy Thwaites, Maia A. Rabaa, Marc Choisy, Hao The Chung, Duy Thanh Pham   +17 more
doaj   +11 more sources

A Case Report of Endogenous Endophthalmitis Associated With a Pyogenic Liver Abscess Caused by Hypervirulent Klebsiella pneumoniae. [PDF]

Immun Inflamm Dis
ABSTRACT Objective Pyogenic liver abscess (PLA) caused by hypervirulent Klebsiella pneumoniae (hvKp) may be complicated by endogenous endophthalmitis (EE) and pneumonia. We herein report a case of a Chinese male patient with PLA and bilateral EE caused by hvKp to highlight the severe clinical outcomes of this condition.
Liu C, Song J, Zhao J, Wei B, Wang P, Liu C, Su H, Tong X, Wu D.   +8 more
europepmc   +2 more sources

Bioactivity of Chitosan Coated Nanoparticles Biosynthesized Using Yeast Against Hypervirulent <i>Klebsiella Pneumoniae</i> (HvKp)

Baghdad Science Journal
Multidrug-resistant (MDR) bacteria are becoming one of the most pressing problems worldwide and are becoming difficult to treat; therefore, nanotechnology is a promising alternative technology.
Sura Alaa Suod, Huda Suhail Abid AL-Hayanni   +1 more
core   +2 more sources

Phenotypic and genotypic study of hypervirulent Klebsiella pneumoniae (hvKp) and molecular characterization of its resistance and virulence determinants [PDF]

Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a significant pathogen due to its increasing incidence. Originally considered an opportunistic bacterium responsible for nosocomial infections in immunocompromised individuals, it now poses a ...
Vallejo Iriarte, Daniela
core   +2 more sources

Emergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China [PDF]

Emerging Microbes & Infections, 2022
Colistin is regarded as a last-resort agent to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria, especially carbapenem-resistant isolates. In recent years, reports of colistin-resistant Klebsiella pneumoniae (CoRKp) are increasing.
Xiaoyu Liu, Yarong Wu, Ying Zhu, Peiyao Jia, Xue Li, Xinmiao Jia, Wei Yu, Yujun Cui, Ruifu Yang, Wei Xia, Yingchun Xu, Qiwen Yang   +11 more
openaire   +3 more sources