Results 81 to 90 of about 2,580 (182)

Clinical and Microbiological Characteristics of Invasive and Hypervirulent Klebsiella pneumoniae Infections in a Teaching Hospital in China

Infection and Drug Resistance, 2020
Lijuan Li, Ziyang Yuan, Danna Chen, Xiaoyan Xie, Bashan Zhang Department of Clinical Laboratory, Affiliated Dongguan People’s Hospital, Southern Medical University, Dongguan, Guangdong 523059, People’s Republic of ChinaCorrespondence: Bashan ...
Li L, Yuan Z, Chen D, Xie X, Zhang B
doaj  

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important emerging pathogen leading to serious clinical outcomes as the multidrug‐resistant (MDR) isolates arise. While K. pneumoniae is a well‐known pathogen in human clinical settings, its risks in nonhuman hosts and potential for cross‐species transmission remain poorly understood. In this study, we performed whole‐genome
Qiu Xu, Cuilong Fan, Yaowei Liu, Xiaofeng Lu, Wei Song, Susu Du, Yao Zhu, Fang Xie, Wanjiang Zhang, Zhong Peng   +9 more
wiley   +1 more source

Outer membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae

, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) is a notorious clinical pathogen that is more likely to cause severe primary and metastatic abscesses. The dissemination of antimicrobial-resistant hvKp isolates has been reported worldwide, posing a great ...
Jingyu Wang (292122), Mei Huang (49698), Qian Wang (32718), Yuneng Hua (9956849), Fan Bu (1563562), Xiaomin Lin (52529), Yiyi Huang (11780453), Xiumei Hu (5076446), Biao Yang (545048), Ruyi Zhang (38360), Juanjiang Chen (9956852), Lei Zheng (106363)   +11 more
core   +1 more source

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns

, 2022
K1/K2 hvKP strains acquire carbapenem-resistance plasmids, known as CR-hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence plasmids, recognized as hv-CRKP.
Jinzuan Wu (13108660), Dakang Hu (647924), Xiao Liu (65413), Ying Zhou (25031), Weiwen Wang (740765), Xiaofei Jiang (2142271), Dongxing Tian (8870936), Wenjie Chen (130753), Qing Mu (2248399)   +8 more
core   +1 more source

Çeşitli klinik örneklerden izole edilen hipervirülan ve klasik klebsiella pneumoniae izolatlarında virülans genleri ve karbapenem direnç genlerinin araştırılması

, 2021
eşitli Klinik Örneklerden İzole Edilen Hipervirülan ve Klasik Klebsiella pneumoniae İzolatlarında Virülans Genleri ve Karbapenem Direnç Genlerinin Araştırılması Klebsiella pneumoniae hastane kökenli ve toplum kökenli enfeksiyonlara sebep olabilen ve ...
MERVE YÜREK
core  

Table_1_In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates.doc

, 2020
ObjectiveThe emergence of carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) strains poses a significant public threat, and effective antimicrobial therapy is urgently needed.
Jingnan Lv (3117978), Hong Du (117108), Siqiang Niu (434025), Yi-Wei Tang (120514), Mingju Hao (770328), Fangyou Yu (325876), Barry N. Kreiswirth (7286546), Liang Chen (73736), Haifang Zhang (314544), Shiqing Cheng (8571153), Xiaohong Shi (506856)   +10 more
core   +1 more source

Rapid detection of K1 hypervirulent Klebsiella pneumoniae by MALDI-TOF MS [PDF]

, 2015
Hypervirulent strains of Klebsiella pneumoniae (hvKP) are genetic variants of Klebsiella pneumoniae which can cause life-threatening community-acquired infection in healthy individuals.
Sheng Chen, Gu eDanxia, Yonglu Huang, Li, J, Fang, Y, Zhang, R, Danxia Gu, Huang, Y, Ying eFang, Chen, S, Yonglu eHuang, Jiaping Li, Chan, WC, Rong eZhang, Edward Wai-Chi Chan, Edward W. Chan, Ying Fang, Sheng eChen, Rong Zhang, Gu, D, Jiaping eLi   +20 more
core   +1 more source

Image_1_In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates.jpg

, 2020
ObjectiveThe emergence of carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) strains poses a significant public threat, and effective antimicrobial therapy is urgently needed.
Jingnan Lv (3117978), Hong Du (117108), Siqiang Niu (434025), Yi-Wei Tang (120514), Mingju Hao (770328), Fangyou Yu (325876), Barry N. Kreiswirth (7286546), Liang Chen (73736), Haifang Zhang (314544), Shiqing Cheng (8571153), Xiaohong Shi (506856)   +10 more
core   +1 more source

Activation of GPR35 by kynurenic acid inhibits IL-1β secretion in macrophages during CR-hvKP-induced pneumonia

International Immunopharmacology
Carbapenemase-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a common pathogen that can cause severe pneumonia. The innate immune response, especially the response of macrophages, plays a crucial role in the host's defense against bacterial infections. Glycolysis is implicated in the modulation of immune functions in macrophages.
Qingyue, Zhang, Bao, Meng, Mingyang, Tang, Chengcheng, Li, Yuexin, Xu, Jinjin, Pan, Liang, Yu, Yasheng, Li, Yi, Yang, Yanyan, Liu, Hongru, Li, Lifen, Hu, Ting, Wu, Jiabin, Li   +13 more
openaire   +2 more sources