Results 71 to 80 of about 15,368 (164)

Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats

Anais da Academia Brasileira de Ciências
: Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis.
JENIFER KOLLING, JANAÍNA KOLLING, ITIANE D. DE FRANCESCHI, VIVIAN S.K. NISHIHIRA, MATHEUS D. BALDISSERA, CLÁUDIA G. PINTO, NATHANA J. MEZZOMO, GUILHERME M. DO CARMO, LUCIANE R. FEKSA, LIANA S. FERNANDES, GILBERTO ORENGO, RODRIGO A. VAUCHER, JANICE L. GIONGO, ANGELA T.S. WYSE, CLOVIS M.D. WANNMACHER, VIRGINIA C. RECH   +15 more
doaj   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, EarlyView.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Liquid chromatography - tandem mass spectroscopic method for the determination Of zerumbone in human plasma and its application to Pharmacokinetics [PDF]

, 2011
A rapid, sensitive, specific and selective LC-MS/MS method for the determination of zerumbone (ZER) in human plasma using 2,4-diamino-6-(4-methoxyphenyl)-1,3,5-triazine (DMTZ) as an internal standard (IS) has been developed and validated.
Abdul, Ahmad Bustamam, Abdullah, Rasedee, E. M. Eid, Eltayeb, Md. Sukari, Mohd. Aspollah, O. Suliman, Fakhr Eldin, S. Fatah, Safa   +5 more
core   +1 more source

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

International Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian, Arnavaz Akhzarmehr, Charise Dallazem Bertol   +2 more
wiley   +1 more source

Cyclodextrin–polysaccharide-based, in situ-gelled system for ocular antifungal delivery

Beilstein Journal of Organic Chemistry, 2014
Fluconazole was studied with two different hydrophilic cyclodextrins (hydroxypropyl-β-cyclodextrin (HPBCD) and sulfobutyl ether-β-cyclodextrin (SBECD)) for the formation of inclusion complexes.
Anxo Fernández-Ferreiro, Noelia Fernández Bargiela, María Santiago Varela, Maria Gil Martínez, Maria Pardo, Antonio Piñeiro Ces, José Blanco Méndez, Miguel González Barcia, Maria Jesus Lamas, Francisco.J. Otero-Espinar   +9 more
doaj   +1 more source

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling. [PDF]

, 2016
The tumor microenvironment (TME) exerts critical pro-tumorigenic effects through cytokines and growth factors that support cancer cell proliferation, survival, motility and invasion.
Flashner-Abramson, E, Karin, M, Levitzki, A, Sanchez-Lopez, E, Shalapour, S, Taniguchi, K, Zhong, Z   +6 more
core   +1 more source

An Australian standard of care for Niemann–Pick disease type C

Internal Medicine Journal, EarlyView.
Abstract Background Niemann–Pick disease type C (NP‐C) is the fifth most prevalent lysosomal disorder in Australia. Diagnostic delay is common, impacted by disease heterogeneity, limited awareness within clinical gateway services and exclusion from state‐based newborn screening programmes.
Michel Tchan, Nicholas Smith, Heidi Peters, Ellie Van Velsen, Catherine Marraffa, Carolyn Ellaway, Katrina Cruz, Shekeeb S. Mohammad, Maina Kava, Joy Yaplito‐Lee, Shanti Balasubramaniam, Yusof Rahman, Brendon Boot, Ashley Bush, Felicity Munro, Leniza Hamoy, Ya Hui Hung, Philippa Johnston, Deanna Carpino, Molly Williams, Sharmila Kiss, Rebecca Quin, Ingrid Sutherland, Mark Walterfang   +23 more
wiley   +1 more source

Preparation and characterization of artemether inclusion complexes with hydroxypropyl-β-cyclodextrin [PDF]

, 2017
Purpose: To investigate experimentally the inclusion of artemether into the cavity of  hydroxypropyl-β-cyclodextrin and examine its effect on the solubility and dissolution rate of the drug.Methods: Inclusion complexes of artemether with hydroxypropyl-β ...
Allagh, Suzane T., Bhatia, Pat G., Ofokansi, Kenneth C., Yahaya, Zwanden Sule   +3 more
core   +2 more sources

Comparative Functionality and Processing of Plant‐Proteins: A Path Toward Optimized Sustainable Plant‐Based Meat Analogues (PBMAs): A Review

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
The review provides a comprehensive comparison in terms comparison of commercially established and emerging plant protein sources, focusing on their structural, rheological, and sensory attributes for developing sustainable plant‐based meat analogues (PBMAs).
Mian N. Riaz, Fariha Irshad, Muhammad Bilal Haider, Debomitra Dey   +3 more
wiley   +1 more source

Inclusion complex of amiodarone hydrochloride with cyclodextrins: preparation, characterization and dissolution rate evaluation

Brazilian Journal of Pharmaceutical Sciences, 2017
This study aimed to improve the water solubility of amiodarone hydrochloride (AMH) via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin.
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Marcela Maurer, Luciane Varini Laporta, Clarice Madalena Bueno Rolim   +4 more
doaj   +1 more source