Results 51 to 60 of about 97,911 (299)

Influences of 5-hydroxytriptamine on sperm hyperactivation and in vitro fertility in rats

open access: yesThe Journal of Reproduction and Development
The neurotransmitter, 5-hydroxytriptamine (5-HT), is well known. Furthermore, it enhances the acrosome reaction, hyperactivation, and in vitro fertilization (IVF) success in hamsters and mice.
Yuki KOYANO, Masakatsu FUJINOKI
doaj   +1 more source

In Vitro Exposure to Glucose Alters the Expression of Phosphorylated Proteins in Platelets

open access: yesBiomedicines, 2023
Diabetes mellitus (DM) is a pro-thrombotic state that can potentially cause serious cardiovascular complications. Platelet hyperactivation plays an important role in these pathological processes, however there is little or no information on the effect of
Mizuho Suzuki   +7 more
doaj   +1 more source

Serotonin-enhanced hyperactivation of hamster sperm [PDF]

open access: yesREPRODUCTION, 2011
The effects of serotonin on reproductive function were examined using hamster spermatozoa. When serotonin at concentrations from 1 fmol/l to 1 μmol/l was added to modified Tyrode's albumin lactate pyruvate (mTALP) medium, hyperactivation was significantly enhanced. Agonists and antagonists of 5-hydroxytryptamine hydrochloride (5-HT) receptors (5-HT2and
openaire   +2 more sources

Capacitation induces changes in metabolic pathways supporting motility of epididymal and ejaculated sperm

open access: yesFrontiers in Cell and Developmental Biology, 2023
Mammalian sperm require sufficient energy to support motility and capacitation for successful fertilization. Previous studies cataloging the changes to metabolism in sperm explored ejaculated human sperm or dormant mouse sperm surgically extracted from ...
Melanie Balbach   +8 more
doaj   +1 more source

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]

open access: yes, 2015
BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio   +9 more
core   +1 more source

Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death

open access: yesJournal of Lipid Research
Sterol-regulatory element binding proteins (SREBPs) are a conserved transcription factor family governing lipid metabolism. When cellular cholesterol level is low, SREBP2 is transported from the endoplasmic reticulum to the Golgi apparatus where it ...
Yanni Xiong   +5 more
doaj   +1 more source

Modulation of the Biocatalytic Properties of a Novel Lipase from Psychrophilic Serratia sp. (USBA-GBX-513) by Different Immobilization Strategies

open access: yesMolecules, 2021
In this work, the effect of different immobilization procedures on the properties of a lipase obtained from the extremophilic microorganism Serratia sp.
Mónica Ruiz   +7 more
doaj   +1 more source

IKKα negatively regulates ASC-dependent inflammasome activation. [PDF]

open access: yes, 2014
The inflammasomes are multiprotein complexes that activate caspase-1 in response to infections and stress, resulting in the secretion of pro-inflammatory cytokines.
Alnemri, Emad S   +19 more
core   +1 more source

The Chemosensing Role of CatSper in Mammalian Sperm: An Updated Review

open access: yesCurrent Issues in Molecular Biology, 2023
After sperm enter the female reproductive tract, the physicochemical and biochemical microenvironment undergoes significant changes. In particular, the large changes in various ions encountered by sperm may alter the physiology of sperm, ultimately ...
Sulun Ke, Tao Luo
doaj   +1 more source

Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia [PDF]

open access: yes, 2010
of poster presentation shown at the 2nd Biennial Schizophrenia International Research Conference on Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in ...
Dawson, Neil   +3 more
core   +1 more source

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