Results 31 to 40 of about 65,627 (261)
Molecular Basis of Human Sperm Capacitation
Frontiers in Cell and Developmental Biology, 2018 In the early 1950s, Austin and Chang independently described the changes that are required for the sperm to fertilize oocytes in vivo. These changes were originally grouped under name of “capacitation” and were the first step in the development of in ...
Lis C. Puga Molina +5 more
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The mechanics of hyperactivation in adhered human sperm [PDF]
Royal Society Open Science, 2014 Hyperactivation is an important phenomenon exhibited by mammalian sperm during the process of acquiring fertilization capacity. The majority of studies have focused on incubation-induced hyperactivation in non-human species, which typically differ in size, shape, and are more homogeneous than human sperm.
Ooi, E H +4 more
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Signaling Enzymes Required for Sperm Maturation and Fertilization in Mammals
Frontiers in Cell and Developmental Biology, 2019 In mammals, motility and fertilizing ability of spermatozoa develop during their passage through the epididymis. After ejaculation, sperm undergo capacitation and hyperactivation in the female reproductive tract – a motility transition that is required ...
Souvik Dey +2 more
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Amygdala hyperactivation in untreated depressed individuals [PDF]
Psychiatry Research: Neuroimaging, 2009 The amygdala participates in the detection and control of affective states, and has been proposed to be a site of dysfunction in affective disorders. To assess amygdala processing in individuals with unipolar depression, we applied a functional MRI (fMRI) paradigm previously shown to be sensitive to amygdala function.
Peluso, Marco A. M. +10 more
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Influences of 5-hydroxytriptamine on sperm hyperactivation and in vitro fertility in rats
The Journal of Reproduction and DevelopmentThe neurotransmitter, 5-hydroxytriptamine (5-HT), is well known. Furthermore, it enhances the acrosome reaction, hyperactivation, and in vitro fertilization (IVF) success in hamsters and mice.
Yuki KOYANO, Masakatsu FUJINOKI
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In Vitro Exposure to Glucose Alters the Expression of Phosphorylated Proteins in Platelets
Biomedicines, 2023 Diabetes mellitus (DM) is a pro-thrombotic state that can potentially cause serious cardiovascular complications. Platelet hyperactivation plays an important role in these pathological processes, however there is little or no information on the effect of
Mizuho Suzuki +7 more
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Frontiers in Cell and Developmental Biology, 2023 Mammalian sperm require sufficient energy to support motility and capacitation for successful fertilization. Previous studies cataloging the changes to metabolism in sperm explored ejaculated human sperm or dormant mouse sperm surgically extracted from ...
Melanie Balbach +8 more
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Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death
Journal of Lipid ResearchSterol-regulatory element binding proteins (SREBPs) are a conserved transcription factor family governing lipid metabolism. When cellular cholesterol level is low, SREBP2 is transported from the endoplasmic reticulum to the Golgi apparatus where it ...
Yanni Xiong +5 more
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Molecules, 2021 In this work, the effect of different immobilization procedures on the properties of a lipase obtained from the extremophilic microorganism Serratia sp.
Mónica Ruiz +7 more
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The Chemosensing Role of CatSper in Mammalian Sperm: An Updated Review
Current Issues in Molecular Biology, 2023 After sperm enter the female reproductive tract, the physicochemical and biochemical microenvironment undergoes significant changes. In particular, the large changes in various ions encountered by sperm may alter the physiology of sperm, ultimately ...
Sulun Ke, Tao Luo
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