Results 21 to 30 of about 65,627 (261)
It is known that sperm and seminal plasma (SP) affect uterine immunity. In cattle, artificial insemination enables breeding by depositing frozen and largely diluted sperm with a negligible amount of SP into the uterus.
Ihshan Akthar +11 more
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Control of hyperactivation in sperm [PDF]
Sperm hyperactivation is critical to fertilization, because it is required for penetration of the zona pellucida. Hyperactivation may also facilitate release of sperm from the oviductal storage reservoir and may propel sperm through mucus in the oviductal lumen and the matrix of the cumulus oophorus.
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Regulation of hyperactivation by PPP2 in hamster spermatozoa [PDF]
Abstract It has been widely accepted that serine/threonine protein phosphatases (PPPs) are associated with the regulation of sperm hyperactivation. In the present study, we examined the types of PPPs associated with the regulation of hamster sperm hyperactivation.
Tatsuya, Suzuki +3 more
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The hippocampus is one of the earliest affected brain regions in Alzheimer´s disease (AD) and its dysfunction is believed to underlie the core feature of the disease- memory impairment.
Aleksandra eMaruszak, Sandrine eThuret
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Diverse Control Mechanisms of the Interleukin-1 Cytokine Family
The majority of interleukin-1 (IL-1) family cytokines lack amino terminal secretion signals or transmembrane domains for secretion along the conventional biosynthetic pathway.
Charles L. Evavold, Jonathan C. Kagan
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TRPV4 is the temperature-sensitive ion channel of human sperm
Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium.
Nadine Mundt +2 more
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Effects of aging and oviductal hormones on testes, epididymides, and sperm of hamster
Purpose Aging is a major cause of decreased fertility. Using hamster, we examined the effects of aging on testes, epididymides, and sperm. Additionally, we examined whether progesterone (P4), melatonin (Mel) and 5‐hydroxytryptamine (5‐HT) mitigated ...
Manami Miyashita, Masakatsu Fujinoki
doaj +1 more source
Hyperactivated endolysosomal trafficking in melanoma
Cutaneous melanoma is an increasingly frequent solid tumor that accounts for 80% of skin cancer-related deaths. Characterized by a complex and heterogeneous genetic background and a notorious functional plasticity, melanoma has shifted from a “black box” to a paradigm of how basic research can be successfully translated into significant improvements of
Alonso-Curbelo, Direna, Soengas, MS
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Regulation of hyperactivation of hamster spermatozoa by progesterone [PDF]
Aim: Although it is accepted that progesterone (P) induces acrosome reaction through non‐genomic regulation, it is not well known if P also affects hyperactivation of sperm.Methods: Hamster spermatozoa were hyperactivated by incubation for 4 h on modified Tyrode's albumin lactate pyruvate medium and recorded on a DVD via a charge‐coupled device ...
Takao, Noguchi +3 more
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Progesterone (P) enhances spermatozoal hyperactivation, a capacitation event. Hyperactivation is associated with successful in vitro fertilization (IVF). In this study, we examined the effects of P on hyperactivation and IVF in mice.
Risa SUZUKI, Masakatsu FUJINOKI
doaj +1 more source

