Results 11 to 20 of about 65,627 (261)

Enhancement of rat spermatozoal hyperactivation by progesterone

open access: yesThe Journal of Reproduction and Development, 2023
Progesterone (P) is a well-known enhancer of hyperactivation which is associated with the success of in vitro fertilization (IVF). In this study, we examined whether P-enhanced hyperactivation affected IVF success in rats.
Yuki MIYAZAWA, Masakatsu FUJINOKI
doaj   +3 more sources

Flagellar hyperactivation of bull and boar spermatozoa [PDF]

open access: yesReproductive Medicine and Biology, 2018
Background In mammals, flagellar hyperactivation is indispensable to sperm fertilization with oocytes in vivo, although there are species differences in regulatory mechanisms for this event.
Hiroshi Harayama
doaj   +3 more sources

Heat-Induced Hyperactivation [PDF]

open access: yesJournal of Assisted Reproduction and Genetics, 1998
The objectives of this study were (1) to determine the sperm hyperactivation and related kinematic parameters at 40 degrees C after using four sperm wash procedures and (2) to correlate the heat-induced hyperactivation data with cases of clinical pregnancies from either artificial insemination or standard in vitro fertilization (IVF).Semen samples (n =
P J, Chan   +4 more
openaire   +2 more sources

Morphology comparison of individually selected hyperactivated and non-hyperactivated human spermatozoa [PDF]

open access: yesHuman Reproduction, 1999
The objective of this study was to compare the morphology of human spermatozoa undergoing hyperactivated motility in vitro with those that were non-hyperactivated (non-hyp). Hyperactivation criteria were established by the Hobson Sperm Tracker (HST), sampling at 25 Hz, as curvilinear velocity (VCL) > or = 70 microns/s, amplitude of lateral head ...
S, Green, S, Fishel
openaire   +2 more sources

Stress hypERactivation in the β-cell [PDF]

open access: yesIslets, 2010
In pancreatic β-cells, the endoplasmic reticulum (ER) is the crucial site for insulin biosynthesis, as this is where the protein-folding machinery for secretory proteins is localized. Perturbations to ER function of the β-cell, such as a high demand for insulin secretion, can lead to an imbalance in protein homeostasis and lead to ER stress.
Fonseca, Sonya G.   +3 more
openaire   +3 more sources

Pharmacological Inactivation of CatSper Blocks Sperm Fertilizing Ability Independently of the Capacitation Status of the Cells: Implications for Non-hormonal Contraception

open access: yesFrontiers in Cell and Developmental Biology, 2021
Cation channel of sperm (CatSper), the main sperm-specific Ca2+ channel, plays a key role in mammalian fertilization, and it is essential for male fertility, becoming an attractive target for contraception.
Ludmila Curci   +4 more
doaj   +1 more source

In vivo characterization of sAC null sperm

open access: yesFrontiers in Cell and Developmental Biology, 2023
Targeted disruption of the soluble adenylyl cyclase (ADCY10; sAC) gene results in male-specific sterility without affecting spermatogenesis, mating behavior, or spermatozoa morphology and count; however, it dramatically impairs sperm motility and ...
Carla Ritagliati   +4 more
doaj   +1 more source

New Approaches to Define The Functional Competency of Human Sperm Subpopulations and Its Relationship to Semen Quality [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2022
Background: This study aimed at comparing a comprehensive set of functional and structural sperm characteristics betweensperm motility fractions and correlating results to the standard semen parameters.
Shannen Keyer   +2 more
doaj   +1 more source

Hyperactivation of mammalian spermatozoa: function and regulation [PDF]

open access: yesReproduction, 2001
Abstract Hyperactivation is a movement pattern observed in spermatozoa at the site and time of fertilization in mammals. It may be critical to the success of fertilization, because it enhances the ability of spermatozoa to detach from the wall of the oviduct, to move around in the labyrinthine lumen of the oviduct, to penetrate mucous
H C, Ho, S S, Suarez
openaire   +2 more sources

Modulatory effect of MG-132 proteasomal inhibition on boar sperm motility during in vitro capacitation

open access: yesFrontiers in Veterinary Science, 2023
A series of biochemical and biophysical changes during sperm capacitation initiates various signaling pathways related to protein phosphorylation leading to sperm hyperactivation, simultaneously with the regulation of proteasomal activity responsible for
Lenka Hackerova   +13 more
doaj   +1 more source

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