Results 11 to 20 of about 9,958 (250)
Influences of 5-hydroxytriptamine on sperm hyperactivation and in vitro fertility in rats
The Journal of Reproduction and DevelopmentThe neurotransmitter, 5-hydroxytriptamine (5-HT), is well known. Furthermore, it enhances the acrosome reaction, hyperactivation, and in vitro fertilization (IVF) success in hamsters and mice.
Yuki KOYANO, Masakatsu FUJINOKI
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Serotonin-enhanced hyperactivation of hamster sperm [PDF]
Reproduction, 2011 Abstract The effects of serotonin on reproductive function were examined using hamster spermatozoa. When serotonin at concentrations from 1 fmol/l to 1 μmol/l was added to modified Tyrode's albumin lactate pyruvate (mTALP) medium, hyperactivation was significantly enhanced. Agonists and antagonists of 5-hydroxytryptamine hydrochloride
Masakatsu Fujinoki
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Hyperactivation is sufficient to release porcine sperm from immobilized oviduct glycans
Scientific Reports, 2022 Fertilizing sperm are retained by adhesion to specific glycans on the epithelium of the oviduct forming a reservoir before sperm are released from the reservoir so fertilization can ensue.
Momal Sharif +7 more
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The mechanics of hyperactivation in adhered human sperm [PDF]
Royal Society Open Science, 2014 Hyperactivation is an important phenomenon exhibited by mammalian sperm during the process of acquiring fertilization capacity. The majority of studies have focused on incubation-induced hyperactivation in non-human species, which typically differ in size, shape, and are more homogeneous than human sperm.
Ooi, E H +4 more
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Behavioral mechanism during human sperm chemotaxis: involvement of hyperactivation.
PLoS ONE, 2011 When mammalian spermatozoa become capacitated they acquire, among other activities, chemotactic responsiveness and the ability to exhibit occasional events of hyperactivated motility--a vigorous motility type with large amplitudes of head displacement ...
Leah Armon, Michael Eisenbach
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Progesterone and estradiol regulate sperm hyperactivation and in vitro fertilization success in mice
The Journal of Reproduction and DevelopmentProgesterone (P) and 17β-estradiol (Eβ) form the well-known hormone pair that regulates sperm capacitation. Here, we examined the regulatory effects of P and Eβ on sperm hyperactivation in mice and evaluated the in vitro fertilization (IVF) success ...
Miyu FUJIKURA, Masakatsu FUJINOKI
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Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.
PLoS ONE, 2012 Regulation of poly(ADP-ribose) (PAR) synthesis and turnover is critical to determining cell fate after genotoxic stress. Hyperactivation of PAR synthesis by poly(ADP-ribose) polymerase-1 (PARP-1) occurs when cells deficient in DNA repair are exposed to ...
Natalie R Gassman +4 more
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CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness [PDF]
, 2021 Aberrant CXCR4 activity has been implicated in lymphoma pathogenesis, disease progression, and resistance to therapies. Using a mouse model with a gain-of-function CXCR4 mutation (CXCR4C1013G) that hyperactivates CXCR4 signaling, we identified CXCR4 as a
Lewis, Richard; https://orcid.org/ +4 more
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Morphology comparison of individually selected hyperactivated and non-hyperactivated human spermatozoa [PDF]
Human Reproduction, 1999 The objective of this study was to compare the morphology of human spermatozoa undergoing hyperactivated motility in vitro with those that were non-hyperactivated (non-hyp). Hyperactivation criteria were established by the Hobson Sperm Tracker (HST), sampling at 25 Hz, as curvilinear velocity (VCL) > or = 70 microns/s, amplitude of lateral head ...
S, Green, S, Fishel
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Stress hypERactivation in the β-cell [PDF]
Islets, 2010 In pancreatic β-cells, the endoplasmic reticulum (ER) is the crucial site for insulin biosynthesis, as this is where the protein-folding machinery for secretory proteins is localized. Perturbations to ER function of the β-cell, such as a high demand for insulin secretion, can lead to an imbalance in protein homeostasis and lead to ER stress.
Fonseca, Sonya G. +3 more
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