Results 41 to 50 of about 93,068 (305)

Hypoxia‐ischemia and brain injury in infants born preterm [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2018
This commentary is on the reviews by Gilles et al. and Galinsky et al. on pages 120–125 and 126–133 of this issue.
openaire   +2 more sources

Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent

open access: yesNeurobiology of Disease, 2005
The incidence of perinatal stroke is ∼0.025%. About two thirds of these patients develop long-lasting neurological deficits. Preconditioning-induced neuroprotection, a phenomenon in which application of a stimulus induces brain ischemic tolerance, is ...
Ping Zhao, Zhiyi Zuo
doaj   +1 more source

Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype

open access: yesFrontiers in Neuroscience, 2022
Hypoxia-ischemia (HI) is the most common acute brain threat in neonates and a leading cause of neurodevelopmental impairment. Exploring the new molecular mechanism of HI brain injury has important clinical translational significance for the next clinical
Yuxiao Sun   +6 more
doaj   +1 more source

Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots [PDF]

open access: yes, 1993
Exposure of nervous tissue to hypoxia results in interstitial acidification. There is evidence for concomitant decrease in extracellular pH to the increase in tissue lactate.
Schneider, Uwe   +7 more
core   +1 more source

Effect of neonatal asphyxia on the impairment of the auditory pathway by recording auditory brainstem responses in newborn piglets: a new experimentation model to study the perinatal hypoxic-ischemic damage on the auditory system.

open access: yesPLoS ONE, 2015
IntroductionHypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system.
Francisco Jose Alvarez   +9 more
doaj   +1 more source

Responses to hypoxia via mTOR : role in endothelial cell proliferation and HIF-1[alpha] stabilization [PDF]

open access: yes, 2005
Ischemic cardiovascular disease and cancer are life-threatening disorders in human mortality. Intensive studies on the etiology of and therapeutics for the diseases are ongoing.
Li, Weimin
core   +1 more source

MiR-335 Regulates Hif-1α to Reduce Cell Death in Both Mouse Cell Line and Rat Ischemic Models. [PDF]

open access: yesPLoS ONE, 2015
Hypoxia inducible factor-1α facilitates cellular adaptation to hypoxic conditions. Hence its tight regulation is crucial in hypoxia related diseases such as cerebral ischemia.
Fu Jia Liu   +6 more
doaj   +1 more source

Late Measures of Brain Injury After Neonatal Hypoxia–Ischemia in Mice [PDF]

open access: yesStroke, 2004
Background and Purpose— This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic–ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology.
Wu, EX   +8 more
openaire   +4 more sources

The change in the hypoxia resistance at chronic cerebral ischemia

open access: yesБюллетень сибирской медицины, 2008
Hypoxia and its related oxidate stress are the direct cause of the neural damage due to chronic cerebral ischemia. Resistance to hypoxia and oxidate stress is the main marker of the human and brain adaptation to chronic ischemia.Hypoxia resistance and ...
Ye. A. Antipenko, A. V. Gustov
doaj   +1 more source

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

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