Results 41 to 50 of about 1,949,320 (295)
Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]
, 1998 Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Domoki, Ferenc +2 more
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Hypoxia‐ischemia and brain injury in infants born preterm [PDF]
Developmental Medicine & Child Neurology, 2018 This commentary is on the reviews by Gilles et al. and Galinsky et al. on pages 120–125 and 126–133 of this issue.
openaire +2 more sources
Changes in arginase isoforms in a murine model of neonatal brain hypoxia–ischemia [PDF]
Pediatric Research, 2020 Arginases (ARG isoforms, ARG-1/ARG-2) are key regulatory enzymes of inflammation and tissue repair; however, their role after neonatal brain hypoxia (H) and hypoxia-ischemia (HI) remains unknown.C57BL/6 mice subjected to the Vannucci procedure on postnatal day (P9) were sacrificed at different timepoints.
Mike, Jana K +3 more
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Neurobiology of Disease, 2005 The incidence of perinatal stroke is ∼0.025%. About two thirds of these patients develop long-lasting neurological deficits. Preconditioning-induced neuroprotection, a phenomenon in which application of a stimulus induces brain ischemic tolerance, is ...
Ping Zhao, Zhiyi Zuo
doaj +1 more source
Frontiers in Neuroscience, 2022 Hypoxia-ischemia (HI) is the most common acute brain threat in neonates and a leading cause of neurodevelopmental impairment. Exploring the new molecular mechanism of HI brain injury has important clinical translational significance for the next clinical
Yuxiao Sun +6 more
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Establishment and identification of a hypoxia-ischemia brain damage model in neonatal rats. [PDF]
Biomed Rep, 2016 The present study was designed to set up a reliable model of severe hypoxia-ischemia brain damage (HIBD) in neonatal rats and several methods were used to identify whether the model was successful. A total of 40 healthy 7-day-old Sprague-Dawley rats were randomly divided into 2 groups: The sham-surgery group (n=18) and the HIBD model group (n=22).
Yao D +5 more
europepmc +4 more sources
PLoS ONE, 2015 IntroductionHypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system.
Francisco Jose Alvarez +9 more
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Late Measures of Brain Injury After Neonatal Hypoxia–Ischemia in Mice [PDF]
Stroke, 2004 Background and Purpose— This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic–ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology.
Wu, EX +8 more
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MiR-335 Regulates Hif-1α to Reduce Cell Death in Both Mouse Cell Line and Rat Ischemic Models. [PDF]
PLoS ONE, 2015 Hypoxia inducible factor-1α facilitates cellular adaptation to hypoxic conditions. Hence its tight regulation is crucial in hypoxia related diseases such as cerebral ischemia.
Fu Jia Liu +6 more
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Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots [PDF]
, 1993 Exposure of nervous tissue to hypoxia results in interstitial acidification. There is evidence for concomitant decrease in extracellular pH to the increase in tissue lactate.
Schneider, Uwe +7 more
core +1 more source