Results 11 to 20 of about 120,663 (190)

Sex Vulnerabilities to Hypoxia-Ischemia at Birth.

open access: yesJAMA Netw Open, 2023
This cross-sectional study examines the incidence of hypoxic ischemic encephalopathy in male vs female neonates.
Chalak LF, Pruszynski JE, Spong CY.
europepmc   +3 more sources

Hypoxia–ischemia in the immature brain [PDF]

open access: yesJournal of Experimental Biology, 2004
SUMMARYThe immature brain has long been considered to be resistant to the damaging effects of hypoxia and hypoxia–ischemia (H/I). However, it is now appreciated that there are specific periods of increased vulnerability, which relate to the developmental stage at the time of the insult.
Susan J, Vannucci, Henrik, Hagberg
openaire   +2 more sources

Cerebral Oxygenation and Metabolism After Hypoxia-Ischemia

open access: yesFrontiers in Pediatrics, 2022
Perinatal hypoxia-ischemia (HI) is still a significant contributor to mortality and adverse neurodevelopmental outcomes in term and preterm infants. HI brain injury evolves over hours to days, and involves complex interactions between the endogenous protective and pathological processes. Understanding the timing of evolution of injury is vital to guide
Simerdeep K. Dhillon   +8 more
openaire   +3 more sources

A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]

open access: yes, 2001
Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Caldwell, Darren   +4 more
core   +1 more source

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

open access: yes, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

Serum Hsp70 antigen: Early diagnosis marker in perinatal asphyxia [PDF]

open access: yes, 2015
BACKGROUND: Perinatal asphyxia is an important cause of mortality and permanent neurological and developmental deficit. Early and accurate diagnosis would help to establish the likely prognosis and may also help in determining the most appropriate ...
Boskabadi, Hassan   +6 more
core   +1 more source

Cerebellar abnormalities following hypoxia alone compared to hypoxic–ischemic forebrain injury in the developing rat brain

open access: yesNeurobiology of Disease, 2011
Two-day-old (P2) rat pups were subjected to either a global hypoxia or to electrocoagulation of the right carotid artery followed by 2.5 h hypoxia. Cellular and regional injury in the cerebellum (CB) was studied at 1, 2 and 19 days using immunohistology.
Valerie Biran   +7 more
doaj   +1 more source

Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]

open access: yes, 2016
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E.   +5 more
core   +1 more source

Histology of Brain Trauma and Hypoxia-Ischemia [PDF]

open access: yesAcademic Forensic Pathology, 2018
Forensic pathologists encounter hypoxic-ischemic (HI) brain damage or traumatic brain injuries (TBI) on an almost daily basis. Evaluation of the findings guides decisions regarding cause and manner of death. When there are gross findings of brain trauma, the cause of death is often obvious.
Petra, Rahaman, Marc R, Del Bigio
openaire   +2 more sources

Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model

open access: yesNeurology Research International, 2012
Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal losses are critical to determine the anatomical substrates responsible for ...
Kathryn M. Buller   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy