Use of Different Parameters and Equations for Calculation of IC50 Values in Efflux Assays: Potential Sources of Variability in IC50 Determination [PDF]
AAPS Journal, 2013 Drug interactions due to efflux transporters may result in one drug increasing or decreasing the systemic exposure of a second drug. The potential for in vivo drug interactions is estimated through in vitro cell assays. Variability in in vitro parameter determination (e.g., IC50 values) among laboratories may lead to different conclusions in in vivo ...
Donna A Volpe
exaly +2 more sources
بررسی اثر کشندگی نانومیکروحبابهای اکسیژن، اوزون و هوا بر رده سلولی سرطان ملانوما [PDF]
Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad., 2022 مقدمه: ملانوم پوستی به عنوان یکی از مهاجمانهترین انواع سرطان پوست است. این بیماری حدود 75 درصد از کل مرگ و میرهای ناشی از سرطان پوست را تشکیل میدهد و تاکنون درمان قطعی برای آن ارائه نشده است.
فاطمه فاضلی +2 more
doaj +1 more source
استخراج ترکیبات فنولی میوه عناب با سیال فوق بحرانی کربن دیاکسید و بهینهسازی و اندازه گیری قدرت آنتیاکسیدانی آن [PDF]
مجله پژوهشهای علوم و صنایع غذایی ایران, 2019 آنتیاکسیدانهای طبیعی اصولاً ترکیبات فنولی، پلیفنولی و کاروتنوئیدی هستند که در میوه درخت عناب یافت میشود. هدف از این مطالعه بهینهسازی شرایط استخراج ترکیبات فنولیک از میوه عناب به دو روش حلالی و روش سیال فوق بحرانی کربن دیاکسید جهت یافتن نقاط بهینه ...
فاطمه فرزانه مقدم +2 more
doaj +1 more source
Applications of Nanobodies in Mycotoxin Detection
Guangdong nongye kexue, 2022 Mycotoxins, as secondary metabolites produced by fungi, are a common threat to food safety and are hazardous to human and livestock health. Mycotoxin contamination of agricultural products causes significant economic losses worldwide.
Shaowen WU +3 more
doaj +1 more source
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2021 Background: Malaria is one of the public health problems in Indonesia. The morbidity rate is still quite high, especially in the eastern part of Indonesia.
Nuriha Marangoh, Suciati, Wiwied Ekasari
doaj +1 more source
Cytotoxicity of Zingiber officinale var. rubrum on HeLa cells and prediction of anti-proliferative activity via the JAK2/STAT3 and hedgehog pathways using a molecular docking approach [PDF]
Pharmaciana, 2023 Cervical cancer is one of the second-leading causes of death in women. The discovery of cancer drug candidates continues to be carried out due to the resistance that occurs in cervical cancer therapy.
Siti Rofida +3 more
doaj +1 more source
The effect of different sweeteners on the free radical scavenging activities, alcohol contents, sugar reductions, and hedonic properties of green tea kombucha [PDF]
Pharmaceutical Sciences Asia, 2023 Green tea (Camellia sinensis) consumption has increased due to the compounds in green tea that have health benefits. Fermenting brewed green tea with a Symbiotic Culture of Bacteria and Yeast (SCOBY) to create green tea kombucha is a suitable strategy to
Muhammad Shidiq Rukman +2 more
doaj +1 more source
Jurnal Biodjati, 2023 Sungkai (Peronema canescens Jack) is a plant that has phenolic content as an antioxidant that can enhance the immune system (immunomodulator). This study aimed to determine the phenolic content and antioxidant activity of Sungkai leaves (Peronema ...
Delima Engga Maretha +3 more
doaj +1 more source
Indonesian Journal of Pharmaceutical Education, 2023 Banana kepok (Musa paradisiaca L.) and pineapple (Ananas comosus L.) are types of fruit that are widely consumed by the community. However, the skin is only disposed of as waste, where the waste of the fruit skin reaches 30% of the whole fruit.
Vivian Fu +2 more
doaj +1 more source
Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by resveratrol derivatives [PDF]
, 2012 As demonstrated previously, resveratrol (3,4',5-trihydroxy-trans-stilbene) inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC), the key rate limiting enzyme in mammalian polyamine synthesis.
John M. Pezzuto +4 more
core +2 more sources