Results 41 to 50 of about 417,281 (310)

Phytochemical Screening and Antioxidant Activity of Tampoi Leaves (Baccaurea macrocarpa (Miq.)Mull.Arg ) by Leaf Age and Solvent Type

open access: yesSains Natural, 2023
Tampoi (Baccaurea macrocarpa (Miq.) Mull.Arg) is a member of the genus Baccaurea which is distributed mainly in the regions of Borneo and Sumatra. The use of tampoi can be done by exploring the potential of tampoi plants as medicinal plants. The research
Sujarwati   +3 more
doaj   +1 more source

IC50 values for FAK inhibitors.

open access: yes, 2013
IC50 values were calculated by fitting the Hill slope model to inhibition curves determined at a concentration of 10 nM purified FAK kinase and 1 mM ATP.
Michael J. Eck (240706)   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Antioxidant activity (IC50) and physicochemical characteristics of mango ginger (Curcuma mangga) kombucha

open access: yesJurnal Gizi Indonesia: The Indonesian Journal of Nutrition
Background: Kombucha is a traditional fermented beverage produced by the symbiotic culture of bacteria and yeast (SCOBY) in sweetened tea. Fermentation is a metabolic process in which microorganisms convert carbohydrates, such as sugars, into other ...
Dewandhaka Putra Andaru   +4 more
doaj   +1 more source

Separation and Purification of ACE Inhibitory Peptide from Jellyfish by Macroporous Resin

open access: yesShipin gongye ke-ji, 2022
In this paper, the separation and purification of jellyfish polypeptide with Angiotensin-I converting enzyme (ACE) inhibitory activity by macroporous adsorption resin was studied from the perspective of molecular polarity.
Tingting CUI   +6 more
doaj   +1 more source

Establishment of Resveratrol IC50.

open access: yes, 2016
N1 immortalized prostate (A), primary prostate (B) or Idiopathic Pulmonary Fibrosis (IPF) lung fibroblasts were treated with ascending concentrations of Resveratrol for 24 hr.
Mehrnaz Gharaee-Kermani (118877)   +2 more
core   +1 more source

MTX IC50 (uM) prediction with BOSO-eBIC model.

open access: yes, 2022
Using the BOSO-eBIC model, prediction of MTX IC50 values in micro molar for cell lines that are not included in the training process: 708 cell lines not present in the GDSC database and 6 cell lines part of the GDSC database for experimental validation ...
Xabier Cendoya (12700321)   +6 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Predictive modelling of peroxisome proliferator-activated receptor gamma (pparγ) ic50 inhibition by emerging pollutants using light gradient boosting machine [PDF]

open access: yes
Peroxisome proliferator-activated receptor gamma (PPARγ), a critical nuclear receptor, plays a pivotal role in regulating metabolic and inflammatory processes.
Yu, Z.   +5 more
core   +1 more source

MTX IC50 (uM) prediction with BOSO-AIC model.

open access: yes, 2022
Using the BOSO-AIC model, prediction of MTX IC50 values in micro molar for cell lines that are not included in the training process: 708 cell lines that are not present in the GDSC database and 6 cell lines part of the GDSC database for experimental ...
Xabier Cendoya (12700321)   +6 more
core   +1 more source

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