Results 231 to 240 of about 111,339,475 (290)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

74. Comparative Analysis of Acellular Dermal Matrices as Vehicle for Stem Cell Therapy Delivery

Plastic and Reconstructive Surgery, Global Open
Margaret W. Lieb, MD, MS, Calvin A. Korba, MD, Michelle Randle, MS, Carrie E. Harrison, BS, Michael W. Neumeister, MD   +4 more
doaj   +1 more source

Refractory recurrent pericarditis associated with MEFV E148Q variant: selective response to IL-1 receptor antagonism. [PDF]

EULAR Rheumatol Open
Haider SW.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Correction: TAFRO syndrome requiring combined IL 6 and IL 1 inhibition: a case report. [PDF]

Front Immunol
Frontiers Production Office.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

D136. Role of Anterior Scalene Muscle Block in Predicting Outcomes in Rib-sparing Vs. First Rib Resection Techniques For Thoracic Outlet Syndrome

Plastic and Reconstructive Surgery, Global Open
Iulianna Taritsa, BA, Kazimir Bagdady, BS, Rushmin Khazanchi, BA, Cristin Coquillard, MD, Rolando Casas Fuentes, BS, Timothy Burke, BA, Puja Jagasia, BA, Lindsay Janes, MD, Ashley Vavra, MD, Jason H. Ko, MD, MBA, FACS   +9 more
doaj   +1 more source

Toll/IL-1 receptor domain-containing adaptor protein plays a crucial role in macrophage-mediated hepatic stellate cell activation in alcoholic liver disease. [PDF]

Front Cell Dev Biol
Patidar P, Obukhov AG, Tasduq SA, Saso L, Baig MS.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

D24. Financial Toxicity Associated With Cleft Palate Repair: A Survey of Family Financial Well-being

Plastic and Reconstructive Surgery, Global Open
Sophia Allison, BA, Hannah Soltani, BA, Emily Chwa, BS, Rachel Donaldson, BS, Arun Gosain, MD   +4 more
doaj   +1 more source