Results 31 to 40 of about 11,450,124 (231)
The International Journal of Biological Markers, 2021 Objective: Our study aimed to observe and evaluate the clinical value of interleukin (IL)-11 in the serum and exhaled breath condensate of patients with non-small cell lung cancer (NSCLC).
Jinnan Wu +6 more
doaj +1 more source
Communications Biology, 2023 All except one cytokine of the Interleukin (IL-)6 family share glycoprotein (gp) 130 as the common β receptor chain. Whereas Interleukin (IL-)11 signal via the non-signaling IL-11 receptor (IL-11R) and gp130 homodimers, leukemia inhibitory factor (LIF ...
Puyan Rafii +11 more
doaj +1 more source
BMC Microbiology, 2019 Background Cytokines play a vital role in the host immune response to infection by initiating the healing process and/or accelerating the progression of the disease in cutaneous leishmaniasis (CL).
Lahiru Sandaruwan Galgamuwa +4 more
doaj +1 more source
Optimal attenuation of experimental autoimmune encephalomyelitis by intravenous immunoglobulin requires an intact interleukin-11 receptor. [PDF]
PLoS ONE, 2014 Intravenous immunoglobulin (IVIg) has been used to treat a variety of autoimmune disorders including multiple sclerosis (MS); however its mechanism of action remains elusive. Recent work has shown that interleukin-11 (IL-11) mRNAs are upregulated by IVIg
Carlyn A Figueiredo +6 more
doaj +1 more source
IL-11 neutralization affects lung injury.
, 2019 Mice were infected with E. coli plus IgG control or anti IL-11 neutralizing antibody. BALF was collected at the time indicated and analyzed for A) IL-11 protein, B) total protein, and C) LDH activity. N = 4–8.
Elise M. Symer (7251545) +6 more
core +1 more source
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
, 2012 IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +2 more sources
Beyond Passive Bystander: Glioblastoma-Educated Astrocyte Suppressing T Cell
Frontiers in Bioscience-LandmarkFaust Akl et al. revealed in Nature a paradigm-shifting mechanism distinct from myeloid-driven immunosuppression, whereby glioblastoma induces T-cell apoptosis via tumor-derived IL-11, prompting astrocytes to reprogram into immunosuppressive tumor ...
Yuan-Yuan Wang, Wei-Lin Jin
doaj +1 more source
Reproductive Biology and Endocrinology, 2003 Embryo implantation, endometrial stromal cell decidualization and formation of a functional placenta are critical processes in the establishment and maintenance of pregnancy. Interleukin (IL)-11 signalling is essential for adequate decidualization in the
Stoikos C +7 more
doaj +1 more source
Targeting IL-11 system as a treatment of pulmonary arterial hypertension
Pharmacological Research, 2023 IL-11 is linked to fibrotic diseases, but its role in pulmonary hypertension is unclear. We examined IL-11's involvement in idiopathic pulmonary arterial hypertension (iPAH).
Javier Milara +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source