Results 31 to 40 of about 7,897,153 (261)
Identification and functional characterization of Interleukin-11 in goldfish (Carassius auratus L.)
Fish and Shellfish Immunology Reports, 2023 Interleukin-11 (IL-11) is a versatile cytokine that modulates cellular differentiation and proliferation in various cell types and tissues. In this study, IL-11 gene from goldfish (Carassius auratus L.) has been identified and characterized.
Moussa Gouife +8 more
doaj +1 more source
The Role of gp130 Cytokines in Tuberculosis
Cells, 2020 Protective immune responses to Mycobacterium tuberculosis (Mtb) infection substantially depend on a delicate balance within cytokine networks. Thus, immunosuppressive therapy by cytokine blockers, as successfully used in the management of various chronic
Kristina Ritter +2 more
doaj +1 more source
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
Human Vaccines & Immunotherapeutics, 2020 The interleukin 6 (IL6) family of proteins regulate important cellular processes and act through a variety of signaling pathways via a shared gp130 receptor.
Anissa A. Widjaja +2 more
doaj +1 more source
Journal of Investigative Dermatology, 2021 Fibroblasts (Fbs) are critical to hypertrophic scar (HTS) formation and were recently demonstrated to be highly heterogeneous. However, Fb heterogeneity in HTSs has not been fully elucidated.
Xin Huang +13 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Cytokines are small signaling proteins that have central roles in inflammation and cell survival. In the half-century since the discovery of the first cytokines, the interferons, over fifty cytokines have been identified. Amongst these is interleukin (IL)
Riley D. Metcalfe +3 more
doaj +1 more source
Biology and Life Sciences Forum, 2023 Current advances in molecular profiling methodologies and the accessibility of multi-omics datasets are paving the way toward a better understanding of heterogeneous diseases, including breast cancer (BC).
Marianna Talia +10 more
doaj +1 more source
Therapeutic Targeting of IL-11 for Chronic Lung Disease.
TIPS - Trends in Pharmacological Sciences, 2021 Interleukin (IL)-11 was originally recognized as an immunomodulatory and hematopoiesis-inducing cytokine. However, although IL-11 is typically not found in healthy individuals, it is now becoming evident that IL-11 may play a role in diverse pulmonary ...
R. Kortekaas +5 more
semanticscholar +1 more source
Lutein attenuates angiotensin II- induced cardiac remodeling by inhibiting AP-1/IL-11 signaling
Redox Biology, 2021 Rationale Oxidative stress plays a critical role in the development of cardiac remodeling and heart failure. Lutein, the predominant nonvitamin A carotenoid, has been shown to have profound effects on oxidative stress.
Youming Chen +6 more
semanticscholar +1 more source
IL-11 Regulates Autoimmune Demyelination [PDF]
The Journal of Immunology, 2009 Abstract Current therapies for the autoimmune demyelinating disease multiple sclerosis (MS) target inflammation, but do not directly address neuroprotection or lesion repair. Cytokines of the gp130 family regulate survival and differentiation of both neural and immune cells, and we recently identified expression of the family member ...
Blake T, Gurfein +6 more
openaire +2 more sources
Cellular Physiology and Biochemistry, 2018 Background/Aims: The cytokine interleukin-11 (IL-11) has important pro- and anti-inflammatory functions. It activates its target cells through binding to the IL-11 receptor (IL-11R), and the IL-11/IL-11R complex recruits a homodimer of glycoprotein 130 ...
Maria Agthe +3 more
doaj +1 more source