Results 11 to 20 of about 11,450,124 (231)
IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts [PDF]
Open Life SciencesWang Jun +4 more
doaj +2 more sources
Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling. [PDF]
FASEB J, 2021 Interleukin-11 (IL-11) is a pleiotropic cytokine with both pro- and anti-inflammatory properties. It activates its target cells via binding to the membrane-bound IL-11 receptor (IL-11R), which then recruits a homodimer of the ubiquitously expressed ...
Koch L +7 more
europepmc +2 more sources
Endosomes as Signaling Platforms for IL-6 Family Cytokine Receptors
Frontiers in Cell and Developmental Biology, 2021 Interleukin-6 (IL-6) is the name-giving cytokine of a family of eleven members, including IL-6, CNTF, LIF, and IL-27. IL-6 was first recognized as a B-cell stimulating factor but we now know that the cytokine plays a pivotal role in the orchestration of ...
Dirk Schmidt-Arras, Stefan Rose-John
doaj +1 more source
Interleukin 11 (IL-11): Role(s) in Breast Cancer Bone Metastases
Biomedicines, 2021 Bone metastases represent the main problem related to the progression of breast cancer, as they are the main cause of death for these patients. Unfortunately, to date, bone metastases are incurable and represent the main challenge for the researcher ...
Paola Maroni +3 more
doaj +1 more source
Identification and functional characterization of Interleukin-11 in goldfish (Carassius auratus L.)
Fish and Shellfish Immunology Reports, 2023 Interleukin-11 (IL-11) is a versatile cytokine that modulates cellular differentiation and proliferation in various cell types and tissues. In this study, IL-11 gene from goldfish (Carassius auratus L.) has been identified and characterized.
Moussa Gouife +8 more
doaj +1 more source
The Role of gp130 Cytokines in Tuberculosis
Cells, 2020 Protective immune responses to Mycobacterium tuberculosis (Mtb) infection substantially depend on a delicate balance within cytokine networks. Thus, immunosuppressive therapy by cytokine blockers, as successfully used in the management of various chronic
Kristina Ritter +2 more
doaj +1 more source
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
Human Vaccines & Immunotherapeutics, 2020 The interleukin 6 (IL6) family of proteins regulate important cellular processes and act through a variety of signaling pathways via a shared gp130 receptor.
Anissa A. Widjaja +2 more
doaj +1 more source
, 2023 Systemic sclerosis (SSc) is a rare rheumatic disease characterized by vascular damage, dysregulated immune response, and fibrosis. Interleukin−11 (IL−11) is upregulated in SSc.
Li Zhao (147498) +12 more
core +1 more source
Frontiers in Immunology, 2020 Cytokines are small signaling proteins that have central roles in inflammation and cell survival. In the half-century since the discovery of the first cytokines, the interferons, over fifty cytokines have been identified. Amongst these is interleukin (IL)
Riley D. Metcalfe +3 more
doaj +1 more source
Biology and Life Sciences Forum, 2023 Current advances in molecular profiling methodologies and the accessibility of multi-omics datasets are paving the way toward a better understanding of heterogeneous diseases, including breast cancer (BC).
Marianna Talia +10 more
doaj +1 more source