Results 271 to 280 of about 1,816,357 (289)

IL-12-Based therapy of malignancies

Drugs of Today, 2001
Interleukin-12 (IL-12) is an important molecule that triggers the activation of natural killer (NK) cells and T-cells, the development of T helper type 1 (Th1) cells and the expression of antiangiogenic genes. Novel methods for IL-12 delivery include cell-based ex vivo gene therapy, viral vector-based gene therapy and DNA plasmid-based nonviral gene ...
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The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases

Medical Microbiology and Immunology, 2004
Appropriate induction of a Th1 immune response is required for effective antimicrobial immunity. However, dysregulated Th1 immune responses after infection may also lead to immunopathology. Thus, cell-mediated immune responses have to be tightly regulated. Upon infection, the production of interleukin (IL)-12, a heterodimeric cytokine composed of a p35
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IL-12 Possibilities

Science, 1995
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IL-12 in Autoimmunity

Clinical Immunology and Immunopathology, 1998
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IL-12

Immunology Today, 1999
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Effects of IL‐12 and Antibodies to IL‐12 on Established Granulomatous Colitis in Mice

Annals of the New York Academy of Sciences, 1996
M F, Neurath, I, Fuss, B, Kelsall, K H, Meyer zum Büschenfelde, W, Strober   +4 more
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Mouse interleukin-12 (IL-12) p40 homodimer:

European journal of immunology, 1995
Interleukin-12 (IL-12) is a cytokine that has regulatory effects on T and natural killer (NK) cells and is composed of two disulfide-bonded subunits, p40 and p35. It was recently reported that supernatants from cultures of mouse IL-12 (moIL-12) p40-transfected COS cells could inhibit IL-12-dependent responses in vitro (Mattner, F., et al., Eur.
Gillessen Sommer, Silke, Carvajal, D, Ling, P, Podlaski, F.J, Stremlo, D.L, Familletti, P.C, Gubler, U, Presky, D.H, Stern, A.S, Gately, M.K   +9 more
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The IL-12 p40 homodimer as a specific antagonist of the IL-12 heterodimer

Immunology Today, 1995
Tieno Germann, Erwin Rüde
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IL-12

2001
Katherine A. Fitzgerald, Luke A.J. O'Neill, Andy J.H. Gearing, Robin E. Callard   +3 more
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IL-12

2011
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