Results 21 to 30 of about 5,540,448 (336)
GENERATION OF IL-17 IMMUNE RESPONSE IN OBESE PATIENTS WITH ASTHMA
Наука и инновации в медицине, 2017 Aim - to investigate the influence of IL-17, IL-10 on the level of asthma control among obese patients. Materials and methods. 79 patients with asthma aged from 18 to 65 years were enrolled in our study and categorized into three groups according to ...
MS S Nurdina, VI I Kupaev, OV V Sazonova
doaj +1 more source
COVID-19: a case for inhibiting IL-17?
Nature reviews. Immunology, 2020 IL-17 and IL-17 receptor inhibitors boast an impressive safety history and are widely available. Here, we argue that targeting IL-17 is immunologically plausible as a strategy to prevent acute respiratory distress syndrome (ARDS) in coronavirus disease ...
Omar Pacha, M. Sallman, S. Evans
semanticscholar +1 more source
Actas Dermo-Sifiliográficas, 2014 IL-17 immunity has been shown to be essential for mucocutaneous protection against Candida albicans in mice and humans. However, mice with defective IL-17 immunity display broader susceptibility, as they are also prone to infections with diverse infectious agents at various sites.
Yun Ling +3 more
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IL-17 in obesity and adipogenesis [PDF]
Cytokine & Growth Factor Reviews, 2010 The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic low-grade inflammation, suggesting that IL-17 may impact adipose tissue. However, the role of IL-17 in obesity is largely unexplored. Emerging studies indicate that obesity
Mushtaq Ahmed, Sarah L. Gaffen
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IL-17: good fear no tears [PDF]
Nature Immunology, 2020 Cytokines are well-known mediators of the immune response, but, recently, pleiotropic roles in the central nervous system have started to be uncovered. It is now shown that IL-17 directly modulates fear behavior in mice.
Rua, Réjane, Pujol, Nathalie
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The Role of IL-17 Cytokines in Psoriasis
ImmunoTargets and Therapy, 2021 Psoriasis is a chronic inflammatory skin condition associated with immune dysregulation. The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically important role in the pathogenesis of psoriasis. The IL-17 effectors (IL-17A, IL-17C, IL-17E, and IL17F) act on keratinocytes, endothelial cells, and immune cells to stimulate ...
Megan Mosca +5 more
openaire +7 more sources
A case control study on the role of interleukin 17 in the pathogenesis of vitiligo
Pigment International, 2022 Background: Interleukin 17 (IL-17) has recently been implicated in the pathogenesis of vitiligo by many studies but it is unclear whether it has any definitive role in causing depigmentation.
Priyanka Karagaiah +1 more
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IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease.
Cell Reports, 2020 Neuroinflammation in patients with Alzheimer's disease (AD) and related mouse models has been recognized for decades, but the contribution of the recently described meningeal immune population to AD pathogenesis remains to be addressed.
Helena C. Brigas +17 more
semanticscholar +1 more source
Journal of Experimental Medicine, 2010 ![Figure][1] APS-I patients harbored autoantibodies against IFN- α , IL-17A, IL-17F, and IL-22. Two new studies suggest why patients with the autoimmune disorder APS-I are susceptible to chronic yeast infections.
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IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis.
Journal of Clinical Investigation, 2020 Senescent cells (SnCs) are implicated in the pathogenesis of age-related diseases including osteoarthritis (OA), in part via expression of a senescence-associated secretory phenotype (SASP) that includes immunologically relevant factors and cytokines. In
Heather J. Faust +15 more
semanticscholar +1 more source