Results 31 to 40 of about 65,138,242 (275)

Exploring new frontiers in the pulsed power laboratory: Recent progress

open access: yesResults in Physics, 2015
One of the most fundamental processes in the Universe, nucleosynthesis of elements drives energy production in stars as well as the creation of all atoms heavier than hydrogen.
S. Adamenko   +14 more
doaj   +1 more source

IL-21 and Sjögren's syndrome [PDF]

open access: yesArthritis Research & Therapy, 2011
Treatment of Sjögren's syndrome is almost entirely symptomatic. A lack of true understanding of the underlying immunological pathology of the disease prevents directed therapy. Interleukin-21 (IL-21) is elevated in the serum of patients with this disease and is expressed by the lymphocytes infiltrating the salivary glands.
openaire   +2 more sources

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]

open access: yes, 2014
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M.   +5 more
core   +1 more source

IL-21 augments rapamycin in expansion of alpha fetoprotein antigen specific stem-cell-like memory T cells in vitro

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: Alloreactive tumor specific T cells are important arsenals of the adaptive immune system in the fight against tumors. However, stem cell-like memory T cells (Tscm) provide the key to effective elimination of tumor cells.
Victor Tunje Jeza   +5 more
doaj   +1 more source

Affinity of MEDI7169 to human and cyno-IL-21.

open access: yes, 2019
Affinity of MEDI7169 to human and cyno-IL-21.
Rachel Ettinger (6264008)   +12 more
core   +1 more source

IL-21 Rescues the Defect of IL-10-Producing Regulatory B Cells and Improves Allergic Asthma in DOCK8 Deficient Mice

open access: yesFrontiers in Immunology, 2021
Mutations in human DOCK8 cause a combined immunodeficiency syndrome characterized by allergic diseases such as asthma and food allergy. However, the underlying mechanism is unclear.
Jinqiu Jiang   +13 more
doaj   +1 more source

New Approaches in Immunotherapy of Behçet Disease [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2013
Behçet Disease (BD) is an autoimmune disorder with recurrent ocular, vascular, central nervous system, articular, mucocutaneous, and gastrointestinal manifestations with unclear etiology and pathogenesis.
Behzad Baradaran   +3 more
doaj   +1 more source

IL-21 is required for the maintenance and pathogenesis of murine Vγ4+ IL-17-producing γδT cells

open access: yesFrontiers in Immunology, 2023
Murine IL-17-producing γδT (γδT17) cells are divided into two subsets: natural γδT17 (nγδT17) cells, whose development is restricted to the fetal thymus, and inducible γδT17 cells, which require antigen exposure for their IL-17 production and are ...
Junichi Ishikawa   +13 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld   +5 more
wiley   +1 more source

Serum Levels of IL-21 and TGF-β in the Yusho Patients [PDF]

open access: yes, 2013
Aryl hydrocarbon receptor (AhR), recognized as a dioxin receptor, is expressed on the surface of helper T (Th) 17 cells. As PCBs and PCDFs are still detected in the sera of the Yusho patients, we hypothesized dysregulation of Th17 cells in the Yusho ...
清水, 和宏   +3 more
core  

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