Results 41 to 50 of about 65,138,242 (275)

IL-21 downregulated cell surface expression of NKp44 and NKG2D and expression of DAP10 and DAP12

, 2011
Copyright information:Taken from "The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors"http://arthritis-research.com/content/9/6/R125Arthritis Research & Therapy 2007;9(6):R125-R125 ...
Jean Villard (41257), Casimir de Rham (41253), Jean-Michel Dayer (10915), Sabrina Jendly (41255), Gregory Schneiter (41256), Sylvie Ferrari-Lacraz (41254)   +5 more
core   +1 more source

Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression

Frontiers in Immunology, 2023
IL-21 is a multifunctional cytokine linked with the pathophysiology of several autoimmune diseases, including type 1 diabetes. In this study, our aim was to examine plasma IL-21 levels in individuals at different stages of type 1 diabetes progression. We
Anna-Mari Schroderus, Josh Poorbaugh, Samantha McElyea, Stephanie Beasley, Lin Zhang, Kirsti Näntö-Salonen, Reeta Rintamäki, Jussi Pihlajamäki, Jussi Pihlajamäki, Mikael Knip, Mikael Knip, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Toppari, Jorma Ilonen, Robert J. Benschop, Tuure Kinnunen, Tuure Kinnunen   +18 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Level IL-15 and IL-21 in Serum Patients Iraqi with Celiac Disease

Medical Journal of Babylon
Celiac disease (CD) is an autoimmune intestinal illness brought on by gluten in people with certain genetic predispositions, also known as gluten-sensitive enteropathy.
Teeba Azher Altaie, Ghasoun Muhammad Ali
doaj   +1 more source

miR-21-3p/IL-22 Axes Are Major Drivers of Psoriasis Pathogenesis by Modulating Keratinocytes Proliferation-Survival Balance and Inflammatory Response

Cells, 2021
Psoriasis is a chronic inflammatory skin disease that is mediated by complex crosstalk between immune cells and keratinocytes (KCs). Emerging studies have showed a specific psoriatic microRNAs signature, in which miR-21 is one of the most upregulated and
Florence Abdallah, Elodie Henriet, Amandine Suet, Ali Arar, Rudy Clemençon, Jean-Marc Malinge, Gaël Lecellier, Patrick Baril, Chantal Pichon   +8 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Cytokine Expression in Helicobacter pylori-Associated Gastrointestinal Diseases: Insights from Ulcerative Colitis and Colon Cancer

Medical Journal of Babylon
Background: Helicobacter pylori (H. pylori) is one of the most common chronic bacterial infections worldwide, associated with gastritis, peptic ulcer, and stomach cancer.
Wasan Abdul Elah Bakir, Refif Sabih Al-Shawk, Zainab Fadhel Ashoor   +2 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Effect of anti-IL-6 and/or anti-IL-21 treatment on Th17, Th1, and antibody development in CIA mice.

, 2017
Th17 (A) and Th1 (B) levels in draining lymph nodes as measured using flow cytometry, and anti-CII antibody level in serum (C) as measured by ELISA of mice with CIA receiving anti-IL-6 and/or anti-IL-21 treatment.
Wim B. van den Berg (118337), Monique M. Helsen (3716077), Liduine van den Bersselaar (3716074), Renoud J. Marijnissen (158623), Marije I. Koenders (158627), Birgitte Walgreen (3716071), Fons A. van de Loo (118339), Peter M. van der Kraan (714850), Peter L. van Lent (384303), Debbie M. Roeleveld (3716080)   +9 more
core   +1 more source

Observational study of Interleukin-21 (IL-21) does not distinguish Kawasaki disease from other causes of fever in children

Pediatric Rheumatology Online Journal, 2017
Background Kawasaki disease (KD) is a febrile childhood vasculitis of unknown etiology. The diagnosis is highly concerning as over a quarter of children who fail to receive timely treatment with intravenous immunoglobulin (IVIG) will develop coronary ...
Rachel Engelberg, Meghan Martin, Brian H. Wrotniak, Mark Daniel Hicar   +3 more
doaj   +1 more source