Results 91 to 100 of about 1,106,140 (286)
L'interleukine-33, un nouvel acteur de la réponse anti-tumorale dans un modèle murin de cancer du côlon [PDF]
, 2014 L'interleukine-33 (IL-33) est une cytokine nucléaire de la famille des interleukines-1. L'IL-33 est exprimée par de nombreux épithéliums en contact avec l'environnement et peut être libérée sous sa forme pleine taille lors de nécrose.
Mirey, Emilie
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IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3 [PDF]
, 2019 IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response.
Adachi +70 more
core +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
مجله دانشکده پزشکی اصفهان, 2016 Background: Recent evidence suggests that the interleukin-33/interleukin-1 receptor-like 1 (IL-33/IL1RL1) axis plays a critical role in autoimmune and inflammatory disorders; however, its mechanistic role in these diseases has not been clearly defined ...
Maryam Ahmadi +4 more
doaj
Mast cell responses to danger signals [PDF]
, 2012 Detecting and responding to danger is a paramount function of the immune system. Compounds heralding danger can be divided into two groups: exogenous and endogenous danger signals.
Enoksson, Mattias
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis [PDF]
, 2013 Carbon-based nanomaterials (CBN), such as graphene nanosheets (GNS) and multiwalled carbon nanotubes (MWCNT), have been proposed for potential nanomedicine applications such as biomedical devices and carriers for drug delivery.
Brown, Jared M +5 more
core +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Zdorovʹe Rebenka, 2014 The review presents the characteristics of cytokine IL-1F11 (IL-33), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov +2 more
doaj +1 more source
The role and mechanism of IL-33 in gout [PDF]
, 2016 摘要 研究目的：以MSU诱导的小鼠实验性急性痛风为痛风研究模型，来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果： 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化，去除GST标签等步骤，获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例（男39例，女2例）年龄26～91岁，平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本，检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
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