Results 71 to 80 of about 4,627,366 (384)

IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute Colitis

Frontiers in Immunology, 2021
The hallmarks of inflammatory bowel disease are mucosal damage and ulceration, which are known to be high-risk conditions for the development of colorectal cancer.
Nhi Ngo Thi Phuong, Vittoria Palmieri, Alexandra Adamczyk, R. Klopfleisch, J. Langhorst, W. Hansen, A. Westendorf, E. Pastille   +7 more
semanticscholar   +1 more source

IL-33 Ameliorates the Development of MSU-Induced Inflammation Through Expanding MDSCs-Like Cells

Frontiers in Endocrinology, 2019
Interleukin-33 (IL-33), a member of the IL-1 superfamily, has been shown to play a critical role in many diseases through regulating the immune cell responses, including myeloid-derived suppressor cells (MDSCs). Our previous study demonstrated that IL-33
Ke Shang, Yingying Wei, Qun Su, Bing Yu, Ying Tao, Yan He, Youlian Wang, Guixiu Shi, Lihua Duan, Lihua Duan   +9 more
doaj   +1 more source

Evaluation of Serum IL-33, IL-5 and Trace Elements Levels among Asthmatic Patients

Journal of Pure and Applied Microbiology, 2022
The precise relationship between interleukins-33 and IL-5, as well as some trace elements and asthma, is unknown. The target of research was to compare and link the above-mentioned serological parameters in asthmatic patients and healthy controls.
Mayada Noori Iqbal, Sura O. Yosif, Jasim Mohammed Muhsin, Jaleel Samanje   +3 more
doaj   +1 more source

Serum IL-33, a new marker predicting response to rituximab in rheumatoid arthritis [PDF]

, 2016
Background. Recent works have suggested a possible link between IL-33 and B-cell biology. We aimed to study in different cohorts and with an accurate ELISA assay the possible association between serum IL-33 detection and response to rituximab (RTX) in ...
A Ahmed, Alice Courties, AM Gestel van, B Stolarski, Barbara Tolusso, Bineta Ly, D Talabot-Ayer, D Xu, D Xu, E Kunisch, E Rivière, E-J Lee, Edward M. Vital, Elodie Rivière, F Rivellese, FY Liew, Gianfranco Ferraccioli, Houria Hendel Chavez, J Malcolm, J Schmitz, J Sellam, J Sellam, J Sellam, J Shen, Jérémie Sellam, M Broek van den, M Couderc, M Komai-Koma, Martin Soubrier, Maxime Dougados, NL Millar, P Martin, Paul Emery, Paul-Olivier Rouzaire, S Sattler, SK Athari, TC Theoharides, X Mariette, Xavier Mariette, Yassine Taoufik, Z Xiangyang   +40 more
core   +6 more sources

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

Frontiers in Immunology
Interleukin-33 (IL-33) is a nuclear factor and member of the IL-1 cytokine family. IL-33 is mainly expressed by epithelial and endothelial cells and exerts its function through interaction with various immune cells, and binding to its receptor can form ...
Feiya Sheng, Mi Li, Jia-Mei Yu, Siyu Yang, Liang Zou, Guan-Jun Yang, Le-Le Zhang   +6 more
semanticscholar   +1 more source

Cytokines Stimulated by IL-33 in Human Skin Mast Cells: Involvement of NF-κB and p38 at Distinct Levels and Potent Co-Operation with FcεRI and MRGPRX2

International Journal of Molecular Sciences, 2021
The IL-1 family cytokine IL-33 activates and re-shapes mast cells (MCs), but whether and by what mechanisms it elicits cytokines in MCs from human skin remains poorly understood. The current study found that IL-33 activates CCL1, CCL2, IL-5, IL-8, IL-13,
Kristin Franke, Zhao Wang, T. Zuberbier, M. Babina   +3 more
semanticscholar   +1 more source

A Case-Control Study Indicates that no Association Exists Between Polymorphisms of IL-33 and IL-1RL1 and Preeclampsia

Cellular Physiology and Biochemistry, 2016
Background/Aims: Preeclampsia (PE) is a systemic inflammatory response syndrome involving varieties of cytokines, and previous studies have shown that IL-33 and its receptor IL-1RL1 play pivotal roles in the development of it. As a polygenetic hereditary
Xiaoyan Ren, Mingzhen Guo, Caili Liu, Tao Huang, Qiang Li, Mengmeng Han, Weiqing Song, Xiuming Tang, Shiguo Liu   +8 more
doaj   +1 more source

IL-33 and the PKA Pathway Regulate ILC2 Populations Expressing IL-9 and ST2

Frontiers in Immunology, 2022
Type 2 Innate lymphoid cells (ILC2s) are tissue-resident immune cells activated by epithelial-derived alarmins upon tissue damage. They regulate immunity against helminth parasites and allergies by expressing type 2 immune response cytokines including IL-
Enrique Olguín-Martínez, Ofelia Muñoz-Paleta, Blanca E. Ruiz-Medina, Jose Luis Ramos-Balderas, Ileana Licona-Limón, Paula Licona-Limón   +5 more
doaj   +1 more source

Interrelationship and Sequencing of Interleukins4, 13, 31, and 33 – An Integrated Systematic Review: Dermatological and Multidisciplinary Perspectives

Journal of Inflammation Research, 2022
Alin Laurentiu Tatu,1– 3,* Thomas Nadasdy,3,4 Anca Arbune,5,* Valentin Chioncel,6,* Carmen Bobeica,7 Elena Niculet,3,* Alina Viorica Iancu,7 Caterina Dumitru,8 Valentin Tudor Popa,3,9 Nicolas Kluger,10,11 Victor Gabriel Clatici,11 Claudiu
Tatu AL, Nadasdy T, Arbune A, Chioncel V, Bobeica C, Niculet E, Iancu AV, Dumitru C, Popa VT, Kluger N, Clatici VG, Vasile CI, Onisor C, Nechifor A   +13 more
doaj  

Interactions between mast cells and smooth muscle in asthma models [PDF]

, 2014
Allergic asthma is the major phenotype of asthma and is characterized by specific responses to allergens as well as airway hyperresponsiveness (AHR), inflammation and remodelling.
Sjöberg, Lisa
core   +1 more source