Results 51 to 60 of about 4,627,366 (384)
Journal of Asthma and Allergy, 2021 Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY +4 more
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The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation
Biomedicines, 2023 ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leading ...
Giacomina Brunetti +5 more
doaj +1 more source
Cell Death and Disease, 2021 Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder characterized by recurrent eczematous lesions. Interleukin (IL)−33, a cytokine of the IL-1 family, was found to play an important role in the pathogenesis of AD.
Jie Zheng +7 more
semanticscholar +1 more source
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]
, 2016 Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank +5 more
core +1 more source
IL-33 Exacerbates Autoantibody-Induced Arthritis [PDF]
The Journal of Immunology, 2010 Abstract Rheumatoid arthritis pathogenesis comprises dysregulation in both innate and adaptive immunity. There is therefore intense interest in the factors that integrate these immunologic pathways in rheumatoid arthritis. In this paper, we report that IL-33, a novel member of the IL-1 family, can exacerbate anti–glucose-6-phosphate ...
Xu, Damo +11 more
openaire +3 more sources
Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease [PDF]
, 2017 IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and marked infiltration of IgG4-positive cells in multiple organs. Interleukin-33 (IL-33) is a recently described cytokine that is secreted by damaged epithelial cells, macrophages ...
Furukawa Sachiko +14 more
core +1 more source
Effects of IL-33 on HaCAT cell line and psoriasis-like lesion in mouse model [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate the effects of interleukin-33(IL-33)on HaCAT cells and psoriasis-like inflammation induced by imiquimod(IMQ) in mice. Methods Twenty-four hours after HaCAT cells were plated, the cell proliferation and autophagy-related protein ...
DUAN Ya-ju, WANG Wen-qian, HU Hua, FU Dan-dan, SONG Xiang-feng, TIAN Zhong-wei
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Endogenous IL-33 and Its Autoamplification of IL-33/ST2 Pathway Play an Important Role in Asthma. [PDF]
, 2020 IL-33 and its receptor ST2 are contributing factors to airway inflammation and asthma exacerbation. The IL-33/ST2 signaling pathway is involved in both the onset and the acute exacerbations of asthma.
Dumouchel, Justin P +5 more
core
IL‐33/ST2 as a potential target for tumor immunotherapy
European Journal of Immunology, 2021 IL‐33, a member of the IL‐1 family, was initially reported to be expressed constitutively in the nucleus of tissue‐lining and structural cells. However, upon tissue damage or injury, IL‐33 can be released quickly to bind with its cognate receptor ST2 in ...
Wenyi Jiang +3 more
semanticscholar +1 more source
Different members of the IL-1 family come out in different ways: DAMPs vs cytokines?
Frontiers in Immunology, 2013 Intercellular communications control fundamental biological processes required for the survival of multicellular organisms. Secretory proteins are among the most important messengers in this network of information.
Sonia eCarta +2 more
doaj +1 more source