Results 41 to 50 of about 4,627,366 (384)
The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD
Respiratory Research, 2018 Background Interleukin(IL)-33 is an epithelial alarmin important for eosinophil maturation, activation and survival. The aim of this study was to examine the association between IL-33, its receptor expression and airway eosinophilic inflammation in non ...
Damian Tworek +8 more
doaj +1 more source
Bacteriological and Immunological study of kidney failure patients infected with urinary tract infections [PDF]
E3S Web of Conferences, 2023 Urinary tract infections (UTIs) are one of the most common medical conditions in women and men. They are caused by bacteria that enter the urinary tract through the urethra or the skin around the genitals.
Mhana Shahrabanawah Mahdi Yasin +1 more
doaj +1 more source
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline [PDF]
, 2016 Alzheimer’s disease (AD) is a devastating condition with no known effective treatment. AD is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment.
Chan, Ivy C. W. +10 more
core +1 more source
Biotechnology & Biotechnological Equipment, 2018 IL-33 binding to IL1RL1 is involved in asthma. The data show that involvement of the IL33/IL1RL1 genes in asthma is biologically plausible. The objective of this study was to investigate the association of IL33 and IL1R1 gene polymorphisms and serum IL ...
Guangyang Zhang +4 more
doaj +1 more source
Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
doaj +1 more source
IL-33/sST2 axis in The Cardiovascular System: A Brief Review [PDF]
Trends in Pharmaceutical Sciences, 2020 IL-33 is a type of cytokine and a new member of the IL-1 family labeled as an alarmin, which is released under stressful settings. IL-33 is a biomechanically induced protein and is mainly produced by cardiac fibroblasts and is expressed by various cell ...
Negar Firouzabadi, Maryam Dashti
doaj +1 more source
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions
Nature Communications, 2021 Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to soluble factors such as the alarmin IL-33, that is often overexpressed in cancer.
G. Ercolano +16 more
semanticscholar +1 more source
IL-33 Signaling in Lung Injury [PDF]
Translational Perioperative and Pain Medicine, 2016 Interleukin (IL)-33, a member of the IL-1 cytokine super-family, acts as both a traditional cytokine and an intracellular nuclear factor. It is generally released from damaged immune cells and signals through its receptor ST2 in an autocrine and paracrine fashion, plays important roles in type-2 innate immunity, and functions as an "alarmin" or a ...
Jing, Chang +3 more
openaire +2 more sources
Serum sST2 levels predict severe exacerbation of asthma
Respiratory Research, 2018 Background Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in stable asthmatics are a predictor for
Masato Watanabe +11 more
doaj +1 more source
Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis. [PDF]
, 2017 The epithelial and epidermal innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) have pivotal roles in the initiation of allergic inflammation in asthma and atopic dermatitis (AD).
Cheng, D +12 more
core +1 more source