Results 41 to 50 of about 67,088,256 (273)
Background/Aims: Preeclampsia (PE) is a systemic inflammatory response syndrome involving varieties of cytokines, and previous studies have shown that IL-33 and its receptor IL-1RL1 play pivotal roles in the development of it. As a polygenetic hereditary
Xiaoyan Ren +8 more
doaj +1 more source
The curious case of IL‐33 in homeostasis and infection [PDF]
AbstractThe importance of interleukin (IL)‐33 in promoting effective antiviral immune responses is evident, yet the critical cellular sources of IL‐33 in homeostasis and infection are largely unknown. In this issue of the European Journal of Immunology, Aparicio‐Domingo et al. [Eur. J. Immunol. 2021.
Reza Nadafi, Ramon Arens
openaire +4 more sources
IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3
Background/Aims: Sepsis is a systemic inflammatory response during infection. There are limited therapeutic options for sepsis patients. Interleukin (IL)-33 has been reported recently with a beneficial effect in mouse sepsis.
Ran Lv +5 more
doaj +1 more source
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
Shedding light on IL-33 in the eye [PDF]
![Figure][1] Insight from Sachin Gadani (left) and Jonathan Kipnis (right) In this issue of JEM , [Xi et al.][2] describe how inflammation is initiated in the retina, studying the alarmin IL-33.
Gadani, Sachin P., Kipnis, Jonathan
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Alin Laurentiu Tatu,1– 3,* Thomas Nadasdy,3,4 Anca Arbune,5,* Valentin Chioncel,6,* Carmen Bobeica,7 Elena Niculet,3,* Alina Viorica Iancu,7 Caterina Dumitru,8 Valentin Tudor Popa,3,9 Nicolas Kluger,10,11 Victor Gabriel Clatici,11 Claudiu
Tatu AL +13 more
doaj
Interleukins are considered to be potential therapeutic targets that can alter the prognosis and disease progression of IBD. IL-21 has proven to be involved in effector Th1, Th2 and Th17 responses.
Alexandros Toskas +5 more
doaj +1 more source
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
IL-33 reduces the development of atherosclerosis [PDF]
Atherosclerosis is a chronic inflammatory disease of the vasculature commonly leading to myocardial infarction and stroke. We show that IL-33, which is a novel IL-1–like cytokine that signals via ST2, can reduce atherosclerosis development in ApoE−/− mice on a high-fat diet.
Miller, Ashley M. +8 more
openaire +3 more sources
IL-33 and IL-18 in Inflammatory Bowel Disease Etiology and Microbial Interactions
The IL-1 cytokines are a newly expanded family, with each of its 11 members playing an important role in health and disease. Typically acting as pro- or anti-inflammatory mediators of first-line innate immunity, their production is particularly important
Michelle A. Williams +2 more
doaj +1 more source

