Results 41 to 50 of about 3,545,338 (242)

Serum sST2 levels predict severe exacerbation of asthma

Respiratory Research, 2018
Background Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in stable asthmatics are a predictor for
Masato Watanabe, Keitaro Nakamoto, Toshiya Inui, Mitsuru Sada, Kojiro Honda, Masaki Tamura, Yukari Ogawa, Takuma Yokoyama, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa   +11 more
doaj   +1 more source

IL-33/ST2 Axis Protects Against Traumatic Brain Injury Through Enhancing the Function of Regulatory T Cells

Frontiers in Immunology, 2022
Traumatic brain injury (TBI) is a devastating condition due to its long-term sequelae on neurological functions. Inflammatory responses after TBI are critical for injury expansion and repair.
Di Xie, Wanying Miao, Fei Xu, Chunli Yuan, Sicheng Li, Chujun Wang, Aditi Junagade, Xiaoming Hu   +7 more
semanticscholar   +1 more source

IL-33/sST2 axis in The Cardiovascular System: A Brief Review [PDF]

Trends in Pharmaceutical Sciences, 2020
IL-33 is a type of cytokine and a new member of the IL-1 family labeled as an alarmin, which is released under stressful settings. IL-33 is a biomechanically induced protein and is mainly produced by cardiac fibroblasts and is expressed by various cell ...
Negar Firouzabadi, Maryam Dashti
doaj   +1 more source

In vitro Culture with Cytokines Provides a Tool to Assess the Effector Functions of ILC2s in Peripheral Blood in Asthma

Journal of Asthma and Allergy, 2021
Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY, Bartemes KR, Bachman KA, Hagan JB, Kita H   +4 more
doaj  

The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation

Biomedicines, 2023
ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leading ...
Giacomina Brunetti, Barbara Barile, Grazia Paola Nicchia, Francesco Onorati, Giovanni Battista Luciani, Antonella Galeone   +5 more
doaj   +1 more source

IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2

Cell Metabolism, 2021
SUMMARY Aging impairs the integrated immunometabolic responses, which have evolved to maintain core body temperature in homeotherms to survive cold stress, infections, and dietary restriction.
Emily L. Goldberg, I. Shchukina, Y. Youm, Seungjin Ryu, Takeshi Tsusaka, Kyrlia C. Young, Christina Camell, Tamara Dlugos, M. Artyomov, V. Dixit   +9 more
semanticscholar   +1 more source

IL-33, an Alarmin of the IL-1 Family Involved in Allergic and Non Allergic Inflammation: Focus on the Mechanisms of Regulation of Its Activity

Cells, 2021
Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) family that is expressed in the nuclei of endothelial and epithelial cells of barrier tissues, among others.
C. Cayrol
semanticscholar   +1 more source

The curious case of IL‐33 in homeostasis and infection [PDF]

European Journal of Immunology, 2020
AbstractThe importance of interleukin (IL)‐33 in promoting effective antiviral immune responses is evident, yet the critical cellular sources of IL‐33 in homeostasis and infection are largely unknown. In this issue of the European Journal of Immunology, Aparicio‐Domingo et al. [Eur. J. Immunol. 2021.
Reza Nadafi, Ramon Arens
openaire   +4 more sources

Effects of IL-33 on HaCAT cell line and psoriasis-like lesion in mouse model [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate the effects of interleukin-33(IL-33)on HaCAT cells and psoriasis-like inflammation induced by imiquimod(IMQ) in mice. Methods Twenty-four hours after HaCAT cells were plated, the cell proliferation and autophagy-related protein ...
DUAN Ya-ju, WANG Wen-qian, HU Hua, FU Dan-dan, SONG Xiang-feng, TIAN Zhong-wei
doaj  

Different members of the IL-1 family come out in different ways: DAMPs vs cytokines?

Frontiers in Immunology, 2013
Intercellular communications control fundamental biological processes required for the survival of multicellular organisms. Secretory proteins are among the most important messengers in this network of information.
Sonia eCarta, Rosa eLavieri, Anna eRubartelli   +2 more
doaj   +1 more source