Results 21 to 30 of about 3,545,338 (242)

Predicting Immuno-Metabolic Complications After Allogeneic Hematopoietic Cell Transplant with the Cytokine Interleukin-33 (IL-33) and its Receptor Serum-Stimulation 2 (ST2)

open access: yesClinical Hematology International, 2020
Patients undergoing allogeneic hematopoietic cell transplantation (HCT) are at risk for numerous acute and long-term complications from this procedure. Post-transplant diabetes mellitus (PTDM) is a common but under-recognized problem.
Uttam K. Rao, Brian G. Engelhardt
doaj   +1 more source

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

open access: yesImmunity, 2021
Summary Alternatively activated macrophages (AAMs) contribute to the resolution of inflammation and tissue repair. However, molecular pathways that govern their differentiation have remained incompletely understood.
Maria Faas   +25 more
semanticscholar   +1 more source

Lung epithelium is the major source of IL-33 and is regulated by IL-33-dependent and IL-33-independent mechanisms in pulmonary cryptococcosis [PDF]

open access: yesPathogens and Disease, 2016
Inhalation of the fungus Cryptococcus neoformans (C. neoformans) results in pulmonary cryptococcosis associated with IL-33-dependent type 2 immunity. Lung epithelium represents the initial contact site of infection. The role of IL-33 in type 2 immunity has been analyzed, but the source of this cytokine and its effect on lung epithelial cell function in
Laura, Heyen   +6 more
openaire   +2 more sources

Reciprocal regulation of IL-33 receptor–mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance IL-33R mediates local inflammatory responses and plays crucial roles in the pathogenesis of immune diseases. In this study, we identified USP38, which negatively regulates IL-33-triggered signaling by mediating K27-linked deubiquitination of
Xue-Mei Yi   +4 more
semanticscholar   +1 more source

IL-33 and IL-33 Receptors in Host Defense and Diseases

open access: yesAllergology International, 2010
Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-1 and IL-18. IL-33 is considered to be crucial for induction of Th2-type cytokine-associated immune responses such as host defense against nematodes and allergic diseases by inducing production of such Th2-type cytokines as IL-5 and IL-13 by Th2 cells, mast cells ...
Oboki, Keisuke   +4 more
openaire   +2 more sources

Bacteriological and Immunological study of kidney failure patients infected with urinary tract infections [PDF]

open access: yesE3S Web of Conferences, 2023
Urinary tract infections (UTIs) are one of the most common medical conditions in women and men. They are caused by bacteria that enter the urinary tract through the urethra or the skin around the genitals.
Mhana Shahrabanawah Mahdi Yasin   +1 more
doaj   +1 more source

Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

open access: yesImmunity, 2021
Summary To accommodate the changing needs of the developing brain, microglia must undergo substantial morphological, phenotypic and functional reprogramming.
Danyang He   +19 more
semanticscholar   +1 more source

IL-33 biology in cancer: An update and future perspectives.

open access: yesCytokine, 2022
Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that is constitutively expressed in the nucleus of epithelial, endothelial and fibroblast-like cells.
W. J. Yeoh, V. Vu, P. Krebs
semanticscholar   +1 more source

Interleukin‐33 (IL‐33): A nuclear cytokine from the IL‐1 family

open access: yesImmunological Reviews, 2018
Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both during homeostasis and inflammation.
C. Cayrol, J. Girard
semanticscholar   +1 more source

The central role of IL-33/IL-1RL1 pathway in asthma: From pathogenesis to intervention.

open access: yesPharmacology and Therapeutics, 2021
Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor, Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma.
A. Saikumar Jayalatha   +4 more
semanticscholar   +1 more source

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