Results 31 to 40 of about 67,088,256 (273)

In vitro Culture with Cytokines Provides a Tool to Assess the Effector Functions of ILC2s in Peripheral Blood in Asthma

open access: yesJournal of Asthma and Allergy, 2021
Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY   +4 more
doaj  

IL-33 Deals with the Gray Matter [PDF]

open access: yesImmunity, 2018
The central nervous system undergoes extensive postnatal synapse remodeling that is critical for the formation of mature neural circuits. In a recent issue of Science, Vainchtein et al. (2018) describe an additional role for astrocyte-derived interleukin-33 (IL-33) in promoting synapse refinement by microglia in the developing brain.
Charlène, Delmas, Elise, Dalmas
openaire   +2 more sources

IL-33/sST2 axis in The Cardiovascular System: A Brief Review [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2020
IL-33 is a type of cytokine and a new member of the IL-1 family labeled as an alarmin, which is released under stressful settings. IL-33 is a biomechanically induced protein and is mainly produced by cardiac fibroblasts and is expressed by various cell ...
Negar Firouzabadi, Maryam Dashti
doaj   +1 more source

Serum sST2 levels predict severe exacerbation of asthma

open access: yesRespiratory Research, 2018
Background Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in stable asthmatics are a predictor for
Masato Watanabe   +11 more
doaj   +1 more source

The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation

open access: yesBiomedicines, 2023
ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leading ...
Giacomina Brunetti   +5 more
doaj   +1 more source

Effects of IL-33 on HaCAT cell line and psoriasis-like lesion in mouse model [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective To investigate the effects of interleukin-33(IL-33)on HaCAT cells and psoriasis-like inflammation induced by imiquimod(IMQ) in mice. Methods Twenty-four hours after HaCAT cells were plated, the cell proliferation and autophagy-related protein ...
DUAN Ya-ju, WANG Wen-qian, HU Hua, FU Dan-dan, SONG Xiang-feng, TIAN Zhong-wei
doaj  

Different members of the IL-1 family come out in different ways: DAMPs vs cytokines?

open access: yesFrontiers in Immunology, 2013
Intercellular communications control fundamental biological processes required for the survival of multicellular organisms. Secretory proteins are among the most important messengers in this network of information.
Sonia eCarta   +2 more
doaj   +1 more source

Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors

open access: yesFrontiers in Immunology, 2020
Cytokines are small secreted proteins that among many functions also play key roles in the orchestration of inflammation in host defense and disease.
Aurora Holgado   +15 more
doaj   +1 more source

Interleukin-31: A Pro-inflammatory Oriented Cytokine

open access: yesFrontiers in Bioscience-Landmark
Type 2 immunity is represented by T helper 2 (Th2) lymphocytes and the cytokines produced downstream (Interleukin (IL)-4, IL-13, IL-31). They are increasingly recognized as pivotal mediators in the pathogenesis of immune-mediated dermatological ...
Giuseppe Murdaca   +3 more
doaj   +1 more source

IL-33-stimulated early phase IL-6 production.

open access: yes, 2018
(a) Representative cytograms of intracellular IL-6 (90 minute activation) analyzed via flow cytometry. (b) Representative histogram of intracellular IL-6.
Nicholas A. Pullen (5983337)   +2 more
core   +1 more source

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