Results 31 to 40 of about 3,545,338 (242)
IL-33 Signaling in Lung Injury [PDF]
Translational Perioperative and Pain Medicine, 2016 Interleukin (IL)-33, a member of the IL-1 cytokine super-family, acts as both a traditional cytokine and an intracellular nuclear factor. It is generally released from damaged immune cells and signals through its receptor ST2 in an autocrine and paracrine fashion, plays important roles in type-2 innate immunity, and functions as an "alarmin" or a ...
Jing, Chang +3 more
openaire +2 more sources
The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity
Frontiers in Immunology, 2018 Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast-like cells acting as a nuclear protein.
Claudia Afferni +11 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background This study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-inflammatory and anti-inflammatory cytokines) in 90 patients with mild/moderate coronavirus disease 2019 (COVID-19) and 90 healthy controls.
Abdulraheem Y. Majeed +2 more
doaj +1 more source
The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD
Respiratory Research, 2018 Background Interleukin(IL)-33 is an epithelial alarmin important for eosinophil maturation, activation and survival. The aim of this study was to examine the association between IL-33, its receptor expression and airway eosinophilic inflammation in non ...
Damian Tworek +8 more
doaj +1 more source
BMC Immunology, 2022 Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska +5 more
doaj +1 more source
IL-33 Signaling in Sensory Neurons Promotes Dry Skin Itch
Journal of Allergy and Clinical Immunology, 2021 Background: Chronic pruritus, or itch, is common and debilitating, but the neuro-immune mechanisms that drive chronic itch are only starting to be elucidated.
A. Trier +11 more
semanticscholar +1 more source
Serum IL-33 level and IL-33 gene polymorphisms in Behçet’s disease
Rheumatology International, 2014 Behçet's disease (BD) is a chronic inflammatory disease. Increased productions of cytokines including interleukin (IL)-1β and IL-18 are documented, and IL-1α and β gene polymorphisms are associated with susceptibility to the disease. IL-33 is a recently discovered member of IL-1 cytokine family.
Koca S.S. +6 more
openaire +2 more sources
IL-33 Deals with the Gray Matter [PDF]
Immunity, 2018 The central nervous system undergoes extensive postnatal synapse remodeling that is critical for the formation of mature neural circuits. In a recent issue of Science, Vainchtein et al. (2018) describe an additional role for astrocyte-derived interleukin-33 (IL-33) in promoting synapse refinement by microglia in the developing brain.
Charlène, Delmas, Elise, Dalmas
openaire +2 more sources
Biotechnology & Biotechnological Equipment, 2018 IL-33 binding to IL1RL1 is involved in asthma. The data show that involvement of the IL33/IL1RL1 genes in asthma is biologically plausible. The objective of this study was to investigate the association of IL33 and IL1R1 gene polymorphisms and serum IL ...
Guangyang Zhang +4 more
doaj +1 more source
Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
doaj +1 more source