Results 11 to 20 of about 67,088,256 (273)
IL-33 and IL-33-derived DC-based tumor immunotherapy
Experimental and Molecular MedicineInterleukin-33 (IL-33), a member of the IL-1 family, is a cytokine released in response to tissue damage and is recognized as an alarmin. The multifaceted roles of IL-33 in tumor progression have sparked controversy within the scientific community ...
Myeong-Ho Kang, Yong-Soo Bae
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IL-33 in Rheumatic Diseases [PDF]
Frontiers in Medicine, 2021 Interleukin-33 (IL-33) is a nuclear factor mainly expressed in barrier epithelium, endothelial cells, and fibroblast reticular cells. Some inflammatory cells also express IL-33 under certain conditions.
Yuanji Dong, Jixin Zhong, Lingli Dong
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IL-33 in Mental Disorders [PDF]
Medicina, 2021 Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo +6 more
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Immunity, 2009 The interleukin-1 (IL-1)-like cytokine IL-33 is widely assumed to undergo proteolytic maturation by caspase-1. In this issue of Immunity, Luthi et al. (2009) show that IL-33 is not a caspase-1 substrate.
Dixit, VM, Lamkanfi, Mohamed
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Annals of the Rheumatic Diseases, 2012 Interleukin (IL) 33, a member of the IL-1 family, is the ligand of ST2 that is expressed mainly on activated Th2 cells and mast cells. IL-33 can skew a predominantly Th1 cell population to a mainly Th2 cells phenotype in vivo.
Liew, F.Y.
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IL-33/IL-31 axis in osteoporosis [PDF]
International Journal of Molecular Sciences, 2020 The study of the immunoskeletal interface has led to the discovery of numerous cytokines involved in the regulation of bone remodeling, providing valuable information on the pathogenesis of osteoporosis.
Mariano Suppa +7 more
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IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo [PDF]
, 2014 Rationale: Rhinoviruses are the major cause of asthma exacerbations; however, its underlying mechanisms are poorly understood. We hypothesized that the epithelial cell–derived cytokine IL-33 plays a central role in exacerbation pathogenesis through ...
Maria-Belen Trujillo-Torralbo (4405423) +31 more
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, 2015 BACKGROUND: Mast cell localization within the airway smooth muscle (ASM)-bundle plays an important role in the development of airway hyper-responsiveness (AHR).
E. Gomez (6708803) +13 more
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IL-33 and Airway Inflammation [PDF]
Allergy, Asthma and Immunology Research, 2011 Interleukin-33 (IL-33) is the 11th member of IL-1 cytokine family which includes IL-1 and IL-18. Unlike IL-1β and IL-18, IL-33 is suggested to function as an alarmin that is released upon endothelial or epithelial cell damage and may not enhance acquired immune responses through activation of inflammasome.
Oboki, Keisuke +3 more
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Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]
, 2014 Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid +15 more
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