Results 11 to 20 of about 1,106,140 (286)
IL-33 in Rheumatic Diseases [PDF]
Frontiers in Medicine, 2021 Interleukin-33 (IL-33) is a nuclear factor mainly expressed in barrier epithelium, endothelial cells, and fibroblast reticular cells. Some inflammatory cells also express IL-33 under certain conditions.
Yuanji Dong, Jixin Zhong, Lingli Dong
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IL-33 in Mental Disorders [PDF]
Medicina, 2021 Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo +6 more
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IL-33 and IL-33-derived DC-based tumor immunotherapy
Experimental and Molecular MedicineInterleukin-33 (IL-33), a member of the IL-1 family, is a cytokine released in response to tissue damage and is recognized as an alarmin. The multifaceted roles of IL-33 in tumor progression have sparked controversy within the scientific community ...
Myeong-Ho Kang, Yong-Soo Bae
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Blockade of IL‐33 signalling attenuates osteoarthritis [PDF]
Clinical & Translational Immunology, 2020 Objectives Osteoarthritis (OA) is the most common form of arthritis characterised by cartilage degradation, synovitis and pain. Disease modifying treatments for OA are not available.
Zengliang He +7 more
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Immunity, 2009 The interleukin-1 (IL-1)-like cytokine IL-33 is widely assumed to undergo proteolytic maturation by caspase-1. In this issue of Immunity, Lüthi et al. (2009) show that IL-33 is not a caspase-1 substrate. IL-33 is inactivated by caspase-3 and -7 to prevent an inappropriate immune response during apoptosis, but not in necrosis.
Lamkanfi, Mohamed, Dixit, Vishva M.
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IL-33 and Airway Inflammation [PDF]
Allergy, Asthma and Immunology Research, 2011 Interleukin-33 (IL-33) is the 11th member of IL-1 cytokine family which includes IL-1 and IL-18. Unlike IL-1β and IL-18, IL-33 is suggested to function as an alarmin that is released upon endothelial or epithelial cell damage and may not enhance acquired immune responses through activation of inflammasome.
Oboki, Keisuke +3 more
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IL-33 Exacerbates Acute Kidney Injury [PDF]
Journal of the American Society of Nephrology, 2011 Inflammation contributes to the pathogenesis of acute kidney injury (AKI). IL-33 is a proinflammatory cytokine, but its role in AKI is unknown. Here we observed increased protein expression of full-length IL-33 in the kidney following induction of AKI with cisplatin.
Ali, Akcay +12 more
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IL-33 and IL-33 Receptors in Host Defense and Diseases
Allergology International, 2010 Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-1 and IL-18. IL-33 is considered to be crucial for induction of Th2-type cytokine-associated immune responses such as host defense against nematodes and allergic diseases by inducing production of such Th2-type cytokines as IL-5 and IL-13 by Th2 cells, mast cells ...
Oboki, Keisuke +4 more
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The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity
Frontiers in Immunology, 2018 Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast-like cells acting as a nuclear protein.
Claudia Afferni +11 more
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BMC Immunology, 2022 Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska +5 more
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