Results 1 to 10 of about 2,244,987 (335)

The Role of Some Inflammatory Markers (IL-6 and CRP) in the Pathogenesis of Acute Coronary Syndrome in Iraqi CCU for Heart Diseases

open access: diamondIraqi Journal of Pharmaceutical Sciences, 2017
In this work an enzyme linked immunosorbent assay (ELISA) technique has been used for detection of some inflammatory markers in serum of acute coronary syndrome (ACS)-Patients Admitted to the cardiac care unit (CCU) of Iraqi Centre For Heart Diseases and
Nadia GH. AbdulKarim   +2 more
doaj   +3 more sources

A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer

open access: yesMembranes, 2021
Colorectal cancer (CRC) is the third most frequent cancer worldwide and the second greatest cause of cancer deaths. About 75% of all CRCs are sporadic cancers and arise following somatic mutations, while about 10% are hereditary cancers caused by ...
Mimmo Turano   +4 more
doaj   +1 more source

Subcutaneous IL-6 Inhibitor Sarilumab vs. Standard Care in Hospitalized Patients With Moderate-To-Severe COVID-19: An Open Label Randomized Clinical Trial

open access: yesFrontiers in Medicine, 2022
BackgroundThe use of IL-6 blockers in COVID-19 hospitalized patients has been associated with a reduction in mortality compared to standard care. However, many uncertainties remain pertaining to optimal intervention time, administration schedule, and ...
Rosario García-Vicuña   +15 more
doaj   +1 more source

Treatment with Tocilizumab in Adult Patients with Moderate to Critical COVID‐19 Pneumonia: A Single‐Center Retrospective Study

open access: yesInternational Journal of Infectious Diseases, 2022
Objectives: This study aimed to assess if tocilizumab (TCZ) timing is associated with improved survival. Material and methods: Data obtained from adult patients with moderate/severe/critical COVID-19 and treated with TCZ, who were admitted to the ...
Amanda Radulescu   +2 more
doaj   +1 more source

Exploring the Predictive Value of Inflammatory Biomarkers in COVID-19 Patients: A Prospective Cohort Study in Malang, Indonesia

open access: yesIndonesian Journal of Chemistry, 2023
The objective of this study was to assess the predictive value of inflammatory biomarkers in COVID-19 patients, namely the CRP/albumin ratio (CAR), interleukin 6 (IL-6), IL-6/lymphocyte ratio (IL-6/LY), and neutrophil/lymphocyte ratio (NLR).
Agustin Iskandar   +6 more
doaj   +1 more source

Interleukin-6 mediates delirium-like phenotypes in a murine model of urinary tract infection

open access: yesJournal of Neuroinflammation, 2021
Background Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The pathogenesis
Mohammad Harun Rashid   +8 more
doaj   +1 more source

Serum IL–1β, IL–2, IL–6, and IL–8 levels in schizophrenia subtypes

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The cytokines are considered to be an important topic in immunological studies of schizophrenia. In this clinical study IL-1β, IL-2, IL-6, and IL-8 levels were compared among schizophrenia subtypes and a control group.
Murat Kuloglu   +4 more
doaj   +1 more source

Evaluation of serum levels of interleukins 6, 8, 17 and 22 in acne vulgaris: A cross-sectional study

open access: yesIndian Journal of Dermatology, 2023
Background: Acne vulgaris (AV) is a chronic, multifactorial, inflammatory skin disease, and it is now becoming increasingly clear that the inflammatory pathway is involved at a very early in the pathogenesis of acne.
Sweta Singh   +2 more
doaj   +1 more source

The Role of Interleukin-6, and IL-12+p40 in the Development of Ischemic Heart Disease

open access: yesKufa Journal for Nursing Sciences, 2023
Background: Because low-grade inflammation may play a role in the pathogenesis of coronary heart disease, and pro-inflammatory cytokines govern inflammatory cascades leading to atherosclerosis, and then to ischemic heart disease.
Dina A. A. Al-Roubaey   +4 more
doaj   +1 more source

The immune and metabolic treatment approach of using testosterone on mice models of liver injury

open access: yesFrontiers in Pharmacology, 2023
Background: Natural killer (NK) cells showed an anti-fibrotic effect; however, their function is thought to be impaired in advanced liver injury. In the current study, we aimed to assess the immune and metabolic impact of testosterone on mice models of ...
Johnny Amer   +3 more
doaj   +1 more source

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