Results 11 to 20 of about 13,521,848 (335)
Trust as a mediator in the relationship between childhood sexual abuse and IL-6 level in adulthood [PDF]
, 2020 Childhood sexual abuse (CSA) has been shown to predict the coupling of depression and inflammation in adulthood. Trust within intimate relationships, a core element in marital relations, has been shown to predict positive physical and mental health ...
Chan, Cecilia L. W. +14 more
core +1 more source
The role of IL-6/JAK2/STAT3 signaling pathway in cancers
Frontiers in Oncology, 2022 Interleukin-6 (IL-6) is a pleiotropic cytokine involved in immune regulation. It can activate janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) signaling pathway.
Bei Huang, Xiaoling Lang, Xihong Li
semanticscholar +1 more source
Interleukin-6, age, and corpus callosum integrity. [PDF]
, 2014 The contribution of inflammation to deleterious aging outcomes is increasingly recognized; however, little is known about the complex relationship between interleukin-6 (IL-6) and brain structure, or how this association might change with increasing age.
Bettcher, Brianne M +13 more
core +6 more sources
The immune and metabolic treatment approach of using testosterone on mice models of liver injury
Frontiers in Pharmacology, 2023 Background: Natural killer (NK) cells showed an anti-fibrotic effect; however, their function is thought to be impaired in advanced liver injury. In the current study, we aimed to assess the immune and metabolic impact of testosterone on mice models of ...
Johnny Amer +3 more
doaj +1 more source
Emerging Microbes and Infections, 2020 Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients were considered mild, critically ill patients involving respiratory failure and multiple organ ...
Huan Han +13 more
semanticscholar +1 more source
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]
, 2002 Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR +3 more
core +2 more sources
Immunity, Inflammation and Disease, 2020 Introduction The aim of this study was to give quantitative insight into the number of cytokine molecules needed to activate a target cell and relate this to the physiological consequences of the amounts of cytokines typically detectable in humans.
Morten B. Hansen
doaj +1 more source
medRxiv, 2020 Background: Although the SARS-CoV-2 viral load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2 nucleic acid (RNAaemia) could be detected in a fraction of ...
Xiaohua Chen +11 more
semanticscholar +1 more source
IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment
Frontiers in Oncology, 2022 Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer metastatic dissemination, including the interleukin-6 (IL-6)-mediated ...
Sara G Manore +3 more
semanticscholar +1 more source
IL-6 and IL-8: An Overview of Their Roles in Healthy and Pathological Pregnancies
International Journal of Molecular Sciences, 2022 Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action, mediating innate and adaptive immunity and multiple physiological processes, including protective and regenerative ones.
A. Vilotić +5 more
semanticscholar +1 more source